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fibrosarcoma

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CARDIAC SYNOVIAL SARCOMA: VARIANTS  Left: The monophasic variant of fibrosa...
Published: 15 November 2023
CARDIAC SYNOVIAL SARCOMA: VARIANTS Figure 56-12 CARDIAC SYNOVIAL SARCOMA: VARIANTS Left: The monophasic variant of fibrosarcoma consists only of monomorphic spindle cells that sometimes grow in a fascicular or herringbone arrangement. Right: The biphasic variant contains cells with overt epithel... More about this image found in CARDIAC SYNOVIAL SARCOMA: VARIANTS Left: The monophasic variant of fibrosa...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... to the development of breast sarcomas ( 1 ). In addition to angiosarcoma, other types of sarcoma arising in the breast occur secondary to radiation therapy, including fibrosarcoma, leiomyosarcoma, and extraskeletal osteosarcoma ( 2 , 3 ). Clinical Features. Patients usually present with a hard, mobile, rapidly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch56
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...: VARIANTS Left: The monophasic variant of fibrosarcoma consists only of monomorphic spindle cells that sometimes grow in a fascicular or herringbone arrangement. Right: The biphasic variant contains cells with overt epithelioid morphology in the background of the spindle cell proliferation. CARDIAC...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma . Am J Surg Pathol   2006 ; 30 : 1502 - 12 . 2. de Winkel   N , Becker   K , Vogt   M...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch54
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... survival and improved quality of life ( 88 ). Cardiac Undifferentiated Pleomorphic Sarcoma. The spindle cell areas of angiosarcoma may be difficult, if not impossible, to distinguish from unclassifiable spindle cell sarcomas, fibrosarcomas, or pleomorphic undifferentiated sarcomas. In such tumors...
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OVARIAN <span class="search-highlight">FIBROSARCOMA</span>  A: The solid tumor has central necrosis and degenerat...
Published: 01 August 2023
OVARIAN FIBROSARCOMA Figure 12-2 OVARIAN FIBROSARCOMA A: The solid tumor has central necrosis and degeneration. B: Low-power histologic image shows high cellularity and the presence of necrosis. C: High-power image shows at least moderate nuclear atypia and an elevated mitotic rate. More about this image found in OVARIAN FIBROSARCOMA A: The solid tumor has central necrosis and degenerat...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-12
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... ). Table 12-1 THE 2020 WHO CLASSIFICATION OF SEX CORD-STROMAL TUMORS OF THE OVARY Pure Stromal Tumors  Ovarian fibroma  Ovarian fibrosarcoma  Thecoma  Luteinized thecoma associated with sclerosing peritonitis  Sclerosing stromal tumor  Microcystic stromal tumor  Signet ring...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-13
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... , Jhala   N , Adsay   NV , Wei   S . Sclerosing epithelioid fibrosarcoma of the pancreas . Ann Diagn Pathol   2013 ; 17 : 214 - 6 . 90. Sheng   Q , Xu   W , Liu   J , et al   Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-3
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
.... This entity represents a subset of cervical spindle cell sarcomas, previously variably diagnosed as neurofibrosarcoma, endocervical fibroblastic malignant peripheral nerve sheath tumor, fibrosarcoma, or possibly undifferentiated cervical stromal sarcoma ( 269 , 270 ). Clinical Features.  NTRK...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... DFSP. On occasion, frank fibrosarcoma or pleomorphic sarcoma is seen in association with DFSP (and presumably represents high-grade sarcomatous transformation). These areas have fascicular or herringbone architecture, severe nuclear atypia, evident pleomorphism, and higher mitotic counts (8 to 15...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., fibrous stroma, or more commonly, high-grade, having the morphology of a undifferentiated pleomorphic sarcoma, myxofibrosarcoma, fibrosarcoma, leiomyosarcoma, or osteosarcoma, either in isolation or in combination with other high-grade components ( 390 , 391 ). DEDIFFERENTIATED LIPOSARCOMA Figure 8-102...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... cells in two small clusters of sex cord cells (arrows). Cellular fibromas may simulate the exceptionally rare fibrosarcoma of the testis. There are no established criteria for the distinction of these two tumors in the testis, but it appears reasonable to apply similar criteria to those used...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... of inflammatory myofibroblastic tumor with malignant features (sometimes termed “inflammatory fibrosarcoma” [ 197 ]) in this location, which is a potential pitfall if the cytologic atypia of the lesional cells is not appreciated ( fig. 11-80 ) ( 197 , 198 ). Positivity for ALK rearrangement or staining...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Published: 01 June 2022
10.55418/9781933477190-3
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... the cells usually resemble fibrosarcoma and other fibroblastic tumors ( fig. 3-97 , left). Epithelioid differentiation, however, is identified in some cases ( fig. 3-97 , right), manifesting as occasional microvilli, incomplete basal lamina, intercellular junctions, or tonofibrils. The ultrastructural...
Images
PRIMARY RENAL SCLEROSING EPITHELIOID <span class="search-highlight">FIBROSARCOMA</span> MIMICKING CLEAR CELL SARC...
Published: 01 November 2021
PRIMARY RENAL SCLEROSING EPITHELIOID FIBROSARCOMA MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY Figure 1-97 PRIMARY RENAL SCLEROSING EPITHELIOID FIBROSARCOMA MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY Left: At low power, the hyalinized fibrotic stroma, clear cytoplasm of the neoplastic cells, and embryonal hyperplasia of single entrapped tubules suggest the diagnosis of clear cell sarcoma of the kidney. Right: At higher power, the nuclear hyperchromasia and extensive ropy collagen are not typical of clear cell sarcoma, and instead support sclerosing epithelioid fibrosarcoma, which demonstrates an EWSR1-CREB3L1 gene fusion. More about this image found in PRIMARY RENAL SCLEROSING EPITHELIOID FIBROSARCOMA MIMICKING CLEAR CELL SARC...
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PLEOMORPHIC <span class="search-highlight">FIBROSARCOMA</span>/UNDIFFERENTIATED PLEOMORPHIC SARCOMA  A: Tumor cel...
Published: 01 October 2021
PLEOMORPHIC FIBROSARCOMA/UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 8-57 PLEOMORPHIC FIBROSARCOMA/UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Tumor cells are arranged in fascicles that are oriented in a storiform pattern. Neoplastic collagen is abundant. B: The fibrosarcoma is composed of large hyp... More about this image found in PLEOMORPHIC FIBROSARCOMA/UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Tumor cel...
Images
PLEOMORPHIC <span class="search-highlight">FIBROSARCOMA</span>/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA  A: The tumo...
Published: 01 October 2021
PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 8-58 PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: The tumor cells have elongated nuclei that have coarse chromatin and are mitotically active. B: Fibrosarcoma cells have plump nuclei and eosinophilic cytop... More about this image found in PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: The tumo...
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PLEOMORPHIC <span class="search-highlight">FIBROSARCOMA</span>/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA  A: Frontal ...
Published: 01 October 2021
PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 8-46 PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Frontal radiograph of the leg shows an expansile lytic mass with a trabeculated appearance that has geographic margins. B: Coronal T1-weighted MRI shows th... More about this image found in PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Frontal ...
Images
PLEOMORPHIC <span class="search-highlight">FIBROSARCOMA</span>/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA  A: Frontal ...
Published: 01 October 2021
PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 8-47 PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Frontal radiograph of the knee shows a radiolucent tumor involving the lateral femoral condyle that contains an irregular infarct that is calcified. B: Axi... More about this image found in PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA A: Frontal ...
Images
PLEOMORPHIC <span class="search-highlight">FIBROSARCOMA</span>/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA  Left: Front...
Published: 01 October 2021
PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 8-48 PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Frontal radiograph of the distal femur shows a radiation-associated poorly defined lytic lesion arising in the distal femur in a patient who had previous... More about this image found in PLEOMORPHIC FIBROSARCOMA/ UNDIFFERENTIATED PLEOMORPHIC SARCOMA Left: Front...