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Figure 12-20
Published: 01 December 2024
ADRENAL CORTICAL “FIBROMA” Figure 12-20 ADRENAL CORTICAL “FIBROMA” A: This tumor measured about 7 mm and was an incidental finding in a patient undergoing radical nephrectomy for a clear cell renal cell carcinoma. B: The tumor is densely fibrotic with bland spindle cells and resembles More about this image found in ADRENAL CORTICAL “FIBROMA” A: This tumor measured about 7 mm and was an in...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... to the adrenogenital/gonadal ridge (see chapter 1 ). The former include granulosa cell tumor ( 63 ) and a fibrous tumor of the adrenal gland resembling ovarian fibroma ( fig. 12-20 ). This lesion is possibly related to “ovarian thecal metaplasia” (covered in chapter 1 ), and may have a sex-cord stromal derivation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... validation. NEUROFIBROMATOSIS TYPE 1 SYNDROME Neurofibromatosis type 1 (NF1) is an autosomal dominant disease with an incidence of about 1 in 3,000. It is characterized by multiple café-aulait spots, intertriginous freckling, and neuro-fibromas. Cerebral and spinal tumors, skeletal dysplasia...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch42
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... (sheet-like) calcification of the falx Minor Diagnostic Criteria  Cardiac or ovarian fibroma  Lymphomesenteric or pleural cysts  Childhood medulloblastoma  Cleft lip/palate  Macrocephaly  Bifid ribs or extra ribs  Polydactyly  Ocular anomalies (e.g., cataract, pigmentary...
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Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., such as a scar/keloid, fibroma, or desmoplastic cellular neurothekeoma ( Table 16-1 ). There are also malignant neoplasms with fibrous stroma that can be confused with DM, such as spindle cell carcinomas or sarcomas with stromal desmoplasia. Desmoplastic Melanoma versus Fibrosing Nonmelanocytic Benign Lesions...
Images
Figure 42-1
Published: 15 November 2023
CARDIAC FIBROMA: MAGNETIC RESONANCE IMAGING Figure 42-1 CARDIAC FIBROMA: MAGNETIC RESONANCE IMAGING This large cardiac fibroma (yellow asterisk) located in the left ventricular (LV) free wall is impinging on the LV cavity, while the right ventricle (RV) is spared. More about this image found in CARDIAC FIBROMA: MAGNETIC RESONANCE IMAGING This large cardiac fibroma (ye...
Images
Figure 42-2
Published: 15 November 2023
CARDIAC FIBROMA: SURGICAL EXCISION Figure 42-2 CARDIAC FIBROMA: SURGICAL EXCISION A: This large lobulated cardiac fibroma has scant brown myocardium on the surface. B: Large morcellated cardiac fibroma removed in a piecemeal fashion. C: Cut surface of a surgically excised cardiac fibroma More about this image found in CARDIAC FIBROMA: SURGICAL EXCISION A: This large lobulated cardiac fibroma...
Images
Figure 42-3
Published: 15 November 2023
CARDIAC FIBROMA Figure 42-3 CARDIAC FIBROMA Left: Large septal cardiac fibroma (black asterisk) impinging on both the LV and RV cavities. Right: Cardiac fibroma (black asterisk) within the LV free wall. More about this image found in CARDIAC FIBROMA Left: Large septal cardiac fibroma (black asterisk) imping...
Images
Figure 42-5
Published: 15 November 2023
CARDIAC FIBROMA: VARIABLE CELLULARITY Figure 42-5 CARDIAC FIBROMA: VARIABLE CELLULARITY Cardiac fibromas may be cellular (left) or paucicellular (right). The latter are more common in older patients, while the former are more often seen in younger patients. More about this image found in CARDIAC FIBROMA: VARIABLE CELLULARITY Cardiac fibromas may be cellular (le...
Images
Figure 42-6
Published: 15 November 2023
CARDIAC FIBROMA: MARGINS Figure 42-6 CARDIAC FIBROMA: MARGINS The periphery of cardiac fibromas frequently show tumor extending into adjacent myocardium, seen with hematoxylin and eosin (left) or better highlighted with Masson trichrome staining (right). More about this image found in CARDIAC FIBROMA: MARGINS The periphery of cardiac fibromas frequently show...
Images
Figure 42-7
Published: 15 November 2023
CARDIAC FIBROMA: CALCIFICATION Figure 42-7 CARDIAC FIBROMA: CALCIFICATION Areas of calcification are characteristic of cardiac fibromas. They may be small microcalcifications throughout (left) or large sheet-like areas of calcification (right). More about this image found in CARDIAC FIBROMA: CALCIFICATION Areas of calcification are characteristic o...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... recognition of these tumors. Some, if not many, show features similar to Spitz nevi and present as a flesh-colored, erythematous, brown or black papule, plaque, or nodule. Large tumors may be ulcerated. The clinical impression may be broad, ranging from pyogenic granuloma or fibroma to nevus or melanoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-07
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... Most lesions are amelanotic and relatively paucicellular, giving the lesion at low magnification a scar or fibroma-like appearance. Within the dermal stroma the melanocytes may be arranged in small nests, short fascicles, or as solitary units. Angiomatoid vascular changes may be seen. Lymphocytic...
Images
Figure 42-4
Published: 15 November 2023
FIBROBLASTS OF CARDIAC FIBROMA Figure 42-4 FIBROBLASTS OF CARDIAC FIBROMA Left: Bland, spindle-shaped fibroblasts are the lesional cells. Right: Dense pink collagen is often visible in and among the fibroblasts. More about this image found in FIBROBLASTS OF CARDIAC FIBROMA Left: Bland, spindle-shaped fibroblasts are...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and neck, sun-exposed skin  Blue, blue-black papule, may also look like a fibroma Flesh-colored papule or plaque, may have tan or brown component Histopathologic Findings  Usually no intraepidermal component Often associated with melanoma in situ  Symmetry common Asymmetry often...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch43
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 43-1 DIAGNOSIS OF TUBEROUS SCLEROSIS COMPLEX a Major Diagnostic Features b  Cardiac rhabdomyoma  Hypomelanotic macules (≥3 in number, each ≥5 mm)  Angiofibromas (≥3)  Ungual fibromas (≥2)  Shagreen patch  Multiple retinal hamartomas...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch40
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... fibroma . Thorac Cardiovasc Surg   1983 ; 31 : 254 - 5 . 36. Georghiou   GP , Shapira   Y , Stamler   A , et al . Surgical excision of papillary fibroelastoma for known or potential embolization . J Heart Valve Dis   2005 ; 14 : 843 - 7 . 37. Elbardissi   AW , Dearani   JA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... , Slesnick   TC . Right ventricular inflammatory myofibroblastic tumor characterization by cardiovascular magnetic resonance . J Am Coll Cardiol   2011 ; 57 : e205 . 20. de Montpreville   VT , Serraf   A , Aznag   H , Nashashibi   N , Planche   C , Dulmet   E . Fibroma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch44
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... behind. Distinguishing these from fibromas can be challenging; however, collagen bundles are typically absent and remnant capillary-sized vessels are often seen variably throughout these sclerosed hemangiomas ( fig. 44-7 ). Microscopic Findings. Cardiac hemangiomas are similar to those of soft tissue...