HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) Figure 4-20 HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interstitial edema, tubular epithelial degeneration, congestion, and focal early hemorrhage. (Courtesy of the CDC IDPB) More about this image found in HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interst...

PATHOGENESIS CONTRASTING YELLOW FEVER AND DENGUE Figure 5-10 PATHOGENESIS CONTRASTING YELLOW FEVER AND DENGUE More about this image found in PATHOGENESIS CONTRASTING YELLOW FEVER AND DENGUE

SEVERE YELLOW FEVER Figure 5-11 SEVERE YELLOW FEVER A,B: The liver shows extensive confluent zonal necrosis, which begins in the lobule midzone. (Courtesy of the CDC Infectious Disease Pathology Branch [IDPB]) More about this image found in SEVERE YELLOW FEVER A,B: The liver shows extensive confluent zonal necrosi...

SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) Figure 5-12 SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) A,B: Early, less striking perivenular hepatic necrosis, sinusoidal congestion, and mild steatosis are seen. (Courtesy of the CDC IDPB) More about this image found in SEVERE DENGUE INFECTION/DENGUE HEMORRAGHIC FEVER (DHF) A,B: Early, less st...

LIVER HISTOPATHOLOGY IN LASSA FEVER Figure 10-8 LIVER HISTOPATHOLOGY IN LASSA FEVER Portal tract inflammatory infiltrate and foci of necrosis (A), as well as apoptotic hepatocytes (B) are seen. (Courtesy of the CDC IDPB) More about this image found in LIVER HISTOPATHOLOGY IN LASSA FEVER Portal tract inflammatory infiltrate a...

Q FEVER Figure 12-36 Q FEVER A,B: In the liver, the typical fibrin ring granuloma morphology is seen at low (A) and high (B) power. C: Masson trichrome stain highlights the inflammatory cells and associated circular fibrinoid material deposition. (Courtesy of Dr. D. Jain, Yale University, New Ha... More about this image found in Q FEVER A,B: In the liver, the typical fibrin ring granuloma morphology is...

TYPHOID FEVER Figure 13-15 TYPHOID FEVER A: Small intestine from a typhoid patient shows mural thickening, numerous foci of ulceration, and an area of bowel perforation. B: Postmortem ileum specimen shows raised, irregularly convoluted and discolored Peyer patches with associated necrosis and ul... More about this image found in TYPHOID FEVER A: Small intestine from a typhoid patient shows mural thicke...

TYPHOID FEVER Figure 13-16 TYPHOID FEVER A,B: Extensive necrosis and deep ulceration extending to the muscularis propria are features. Note the prominent lymphohistiocytic infiltrate and the near absence of neutrophils. C: Scant plasma cells are present in the adjacent intact mucosa. More about this image found in TYPHOID FEVER A,B: Extensive necrosis and deep ulceration extending to the...

TYPHOID FEVER Figure 13-17 TYPHOID FEVER A: Base of a cecal ulcer shows the characteristic predominance of histiocytes in the inflammatory infiltrate. B: The histiocytes (Mallory cells), which are also found in draining lymph nodes, have granular cytoplasm due to phagocytosis of necrotic debris ... More about this image found in TYPHOID FEVER A: Base of a cecal ulcer shows the characteristic predominan...

AFRICAN TICK BITE FEVER Figure 14-33 AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prominent purpuric dermal erythrocyte extravasation (B), and vasculitic change with striking fibrinoid necrosis and surrounding predominantly mononuclear inflammatory cell infiltration (C). ... More about this image found in AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prom...

ROCKY MOUNTAIN SPOTTED FEVER Figure 14-35 ROCKY MOUNTAIN SPOTTED FEVER Histopathology of renal (A), lung (B), and brain white matter (C). There are predominantly mononuclear cell inflammatory cell infiltrates and foci of endothelial injury with erythrocyte extravasation. Note the early microglial... More about this image found in ROCKY MOUNTAIN SPOTTED FEVER Histopathology of renal (A), lung (B), and br...

ROCKY MOUNTAIN SPOTTED FEVER Figure 14-36 ROCKY MOUNTAIN SPOTTED FEVER Skin histology showing scant perivascular inflammation on H&E stain (A), with a Rickettsia immunohistochemical stain (B) illustrating striking positivity in relation to a small dermal blood vessel from a skin biopsy. (Courtesy of the CDC IDPB) More about this image found in ROCKY MOUNTAIN SPOTTED FEVER Skin histology showing scant perivascular inf...

BORRELIAL TICK-BORNE RELAPSING FEVER Figure 15-8 BORRELIAL TICK-BORNE RELAPSING FEVER Blood smear demonstrates the typical spirochetes. (Courtesy of the CDC IDPB) More about this image found in BORRELIAL TICK-BORNE RELAPSING FEVER Blood smear demonstrates the typical ...

LASSA VIRUS Figure 10-7 LASSA VIRUS Prominent facial edema (due to increased vascular permeability) in a Lassa fever patient. (Courtesy of the CDC PHIL) More about this image found in LASSA VIRUS Prominent facial edema (due to increased vascular permeability...

SEVERE FLAVIVIRUS INFECTION Figure 5-14 SEVERE FLAVIVIRUS INFECTION A: Early pulmonary edema in dengue. B: Striking intra-alveolar hemorrhage in yellow fever. (Courtesy of the CDC IDPB) More about this image found in SEVERE FLAVIVIRUS INFECTION A: Early pulmonary edema in dengue. B: Striki...

VIRAL IMMUNOHISTOCHEMISTRY Figure 5-13 VIRAL IMMUNOHISTOCHEMISTRY A: Liver tissue shows hepatocyte and Kupffer cell positivity in yellow fever. B: Lung tissue in severe dengue with prominent macrophage staining. (Courtesy of the CDC IDPB) More about this image found in VIRAL IMMUNOHISTOCHEMISTRY A: Liver tissue shows hepatocyte and Kupffer ce...