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CONGENITAL ADRENAL HYPERPLASIA This 18-month-old female was mistakenly ass...
Available to Purchase
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CONGENITAL ADRENAL HYPERPLASIA Figure 2-10 CONGENITAL ADRENAL HYPERPLASIA This 18-month-old female was mistakenly assigned a male gender. The markedly enlarged clitoris resembles a penis. The hypertrophied clitoris had a urethral opening near the base. The rugosity of the partially fused labio More about this image found in CONGENITAL ADRENAL HYPERPLASIA This 18-month-old female was mistakenly ass...
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ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female p...
Available to Purchase
in Clinicopathologic Features of the Adrenal Cortex
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA Figure 3-13 ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female presented with hypertension, facial swelling, and hirsutism. There were elevated steroid metabolites in the urine which could not be suppressed with high-dose More about this image found in ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female p...
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ADRENAL CORTICAL CARCINOMA An ACC from a 32-year-old female weighed 2,200 ...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-8 ADRENAL CORTICAL CARCINOMA An ACC from a 32-year-old female weighed 2,200 g and measured 21 cm in diameter. There were extensive areas of necrosis with foci of vascular invasion. The patient also had pulmonary metastases at the time of diagnosis. More about this image found in ADRENAL CORTICAL CARCINOMA An ACC from a 32-year-old female weighed 2,200 ...
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ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME This adrenal cor...
Available to PurchasePublished: 01 December 2024
ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Figure 5-9 ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME This adrenal cortical adenoma is from a 35-year-old female with Cushing syndrome. The tumor has a confluent brown color due to cells with compact, lipid-de pleted More about this image found in ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME This adrenal cor...
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DISTRIBUTION OF NEUROBLASTOMA BY SEX AND STAGE OVER AGE Nearly 90 percent ...
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in Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
of columns represents female patients. (Fig. 5 from Träger C. Neuroblastoma incidence, biology and outcome: with special emphasis on quantitative analysis of tyrosine hydroxylase mRNA in blood and bone marrow. Stockholm: Karolinska Institute; 2009:27.) More about this image found in DISTRIBUTION OF NEUROBLASTOMA BY SEX AND STAGE OVER AGE Nearly 90 percent ...
Book Chapter
Congenital Disorders of the Adrenal Gland
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... biosynthetic pathways, particularly androgen synthesis. Males with the salt-losing form of 21-hydroxylase deficiency may have signs and symptoms (e.g., vomiting, dehydration, and hypotension) that resemble an addisonian crisis within a few weeks of birth. If the female fetus is exposed to increased androgens...
Book Chapter
Adrenal Cortical Adenoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Pediatric 5th-6th decade M/F Slight male predominance Female predominance Female predominance Equal Potential precursor lesions Aldosterone-producing cell clusters Unknown Unknown Unknown Size Usually <2 cm 3-4 cm Usually <3 cm (mostly case reports, only) 3-4 cm Peculiar...
Book Chapter
Clinicopathologic Features of the Adrenal Cortex
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Cushing syndrome has an incidence of approximately 2 to 3 per 1,000,000 population per year and a prevalence of almost 40 per million population ( 3 ). It is most frequent in females in the 4th to 5th decades, however, sex and age predominance are largely biased by the underlying cause of cortisol...
Book Chapter
Adrenal Cortical Carcinoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the last four decades. This is in accordance with a population-based study from the Netherlands, which reported an incidence of 1 case per million ( 3 ). Like other adrenal diseases, ACC is more frequent in females than males ( 4 ). The female to male ratio ranges from 1.5–2.5 to 1.0; women have a higher...
Book Chapter
Other Adrenal Neoplasms and Tumor-Like Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and an equal sex distribution. Twelve percent of the tumors were bilateral. The estimated incidence at autopsy varies from 0.08 to 0.2 percent; in one study it was 0.01 percent for the age group between 36 and 65 years ( 16 ). A female predominance has been reported in a series of Chinese patients ( 17...
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GRANULOMA INGUINALE OF THE EXTERNAL FEMALE GENITALS There is typical ulcer...
Available to PurchasePublished: 01 September 2024
GRANULOMA INGUINALE OF THE EXTERNAL FEMALE GENITALS Figure 18-18 GRANULOMA INGUINALE OF THE EXTERNAL FEMALE GENITALS There is typical ulceration with a beefy red granulation tissue base. (Courtesy of Dr. M. Gaviria, Pontifica Bolivariana University, Medellín, Colombia) More about this image found in GRANULOMA INGUINALE OF THE EXTERNAL FEMALE GENITALS There is typical ulcer...
Book Chapter
Familial and Syndrome-Related Pheochromocytoma and Paraganglioma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... factor 2 alpha (HIF2A) were identified in two patients presenting with polycythemia and paraganglioma, and one also with a somatostatinoma ( 83 ). Additional patients were reported ( 84 , 85 ) and while initially thought to occur only in females, a male patient was also identified ( 86...
Book Chapter
Pheochromocytoma and Adrenal Medullary Hyperplasia
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... presentations. Among the incidental lesions, 33.34 percent had a mean delay in diagnosis of 22.95 months (4 to 120 months). Among those with symptoms, patients were younger and more often female, had larger tumors, and had higher preoperative hormone levels. Those with a genetic predisposition were the youngest...
Book Chapter
Adrenal Cortical Nodular Diseases
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... macronodular adrenocortical disease (PBMAD) is characterized by multiple bilateral nodules that are larger than 1 cm. It is more frequent in adults, particularly in the 5th decade of life (mean age of 53 years), with a slight female predominance that is observed in sporadic but not in hereditary forms...
Book Chapter
Physiology, Development, and Anatomy of the Adrenal Glands
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of the anatomic relationships during adrenal gland development (see fig. 1-3 ), adrenal cortical tissue can be found later in life anywhere in the vicinity of the fetal adrenal primordium or along the line of descent of the gonads in males and females, including gonadal adnexal structures and, rarely, within...
Book Chapter
Paraganglia and Paragangliomas
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... at diagnosis is in the 5th to 6th decades but the reported age ranges are wide, especially for laryngeal paragangliomas (5 to 85 years) ( 44 ). In contrast to sympathetic paragangliomas, those in the head and neck show a female to male ratio of 2-3 to 1 ( 43 ). In addition, carotid body paragangliomas occur...
Book Chapter
Hereditary Predisposition to Adrenal Cortical Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... description in an adrenal cortical carcinoma of a female patient at the age of 3 years, it was questioned whether this variant was germline or somatic ( 81 ). This same mutation was then identified as germline in a very high percentage of pediatric cases of adrenal cortical tumors from the Paranà region...
Book Chapter
Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... are below 5 years of age at diagnosis. The left side of each pair of columns represents male patients and the right side of each pair of columns represents female patients. (Fig. 5 from Träger C. Neuroblastoma incidence, biology and outcome: with special emphasis on quantitative analysis of tyrosine...
Book Chapter
Systemic Infections
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... summarizes the distinguishing clinical characteristics of the various Plasmodium spp. The life cycle of human plasmodial species is represented in figure 27-1 . The female Anopheles mosquito harbors sporozoites, the infective form of the parasite, in its salivary glands and injects them...
Book Chapter
Sexually Transmitted Infections
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... (misdirected and inverted eyelashes making contact with the cornea), and corneal opacities that lead to blindness Genital Asymptomatic in approximately 70% of female and 50% of male patients Symptomatic patients have urethritis and proctitis in males, and cervicitis in females Adult inclusion...
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