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Figure 4-77

NON-HODGKIN LYMPHOMA OF THE ORAL CAVITY A,B: The lymphoma presents as an e...

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in Oral Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
NON-HODGKIN LYMPHOMA OF THE ORAL CAVITY Figure 4-77 NON-HODGKIN LYMPHOMA OF THE ORAL CAVITY A,B: The lymphoma presents as an extranodal swelling and ulceration involving the palate (A) and the gingiva (B). More about this image found in NON-HODGKIN LYMPHOMA OF THE ORAL CAVITY A,B: The lymphoma presents as an e...
Book Chapter

Neck

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... Figure 7-11 METASTATIC PARAGANGLIOMA This paraganglioma is metastatic to bone and shows large cells with granular eosinophilic cytoplasm filling the marrow spaces. HEMATOLYMPHOID TUMORS OF THE NECK AND CERVICAL LYMPH NODES The head and neck is a common site for nodal and extranodal hematolymphoid...
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Book Chapter

Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... historically debated, at least some are neoplastic and harbor oncogenic mutations. General Features. While RDD classically affects lymph nodes (sinus histiocytosis with massive lymphadenopathy), extranodal cases are frequent in the head and neck region, especially the sinonasal tract ( 17 – 20...
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Book Chapter

Oropharynx

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... arise in the oropharynx, particularly in the palatine tonsil, with the most frequent subtype being mixed cellularity ( 136 – 139 ). Extranodal NK/T-cell lymphoma sometimes involves the palate and oropharynx, more commonly in Asian patients. Mature T-cell lymphomas including anaplastic large...
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Book Chapter

Oral Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... cavity comprise a diverse group of hematologic malignancies and account for 3.5 percent of intraoral cancers ( 256 ). Non-Hodgkin lymphoma (NHL) is the most common type of hematopoietic malignancy affecting the oral cavity, and excluding Waldeyer ring, lymphomas of the oral cavity are extranodal...
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Book Chapter

Nasopharynx

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... ). In a study by Allam et al. ( 127 ), diffuse large B-cell lymphoma represented over 50 percent of primary nasopharyngeal lymphomas ( fig. 3-25 ), followed by follicular lymphoma, and less often T-cell lymphomas and extranodal marginal zone lymphomas. Patients from various...
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Book Chapter

Hypopharynx, Larynx, and Trachea

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... in laryngeal SCC, and extranodal extension is further prognostic as well ( 93 ). For hypopharyngeal SCC patients, 5-year relative survival rates are 32 percent overall, and 59, 33, and 21 percent for localized, nodal metastatic, and distant metastatic disease, respectively ( 115 ). For tracheal SCC, limited...
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Book Chapter

Jaw

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... and CD207 negative. Extranodal sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is characterized by sheets of polygonal and spindled histiocytes with emperipolesis of lymphocytes, and eosinophils are rare. The histiocytes are S-100 protein positive but CD1a and CD207 negative...
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Book Chapter

Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... carcinoma with regional metastases: the prognostic importance of soft tissue metastases and extranodal spread . Ann Surg Oncol   2012 ; 19 : 274 - 9 . 468. Muelleman   T , Chowdhury   NI , Killeen   D , et al . Effect of piecemeal vs en bloc approaches to the lateral temporal bone...
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Book Chapter

Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... lymphomas represent less than 1 percent of non-Hodgkin lymphomas and less than 3 percent of all extranodal lymphomas ( 70 ). In some cases, adrenal involvement is accompanied or followed by more widespread disease, and the categorization as primary versus metastasis is uncertain even with strict exclusion...
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Book Chapter

Adrenal Cortical Carcinoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...     - Vascular invasion     - Atypical mitotic figures     - Necrosis Extent of necrosis Nuclear grade     - Mitotic index and histologic tumor grade     - Ki-67 proliferation index     - Margin status Distance of the tumor to the closest margin Lymph node status Extranodal extension...
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Book Chapter

Lymph Nodes and Bone Marrow

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... lymphoma Chronic active EBV infection of T and NK cells (systemic and cutaneous) Hydroa-vacciniforme Severe mosquito bite allergy Systemic EBV-positive T-cell lymphoproliferative disease of childhood Hemophagocytic lymphocytosis NK/T-cell lymphomas (nodal and extranodal, including nasal type) Aggressive...
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Images
Figure 12-4

EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MAL...

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in Rare Lesions > Tumors of the Mammary Gland
Published: 01 January 2024
EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA) Figure 12-4 EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA) Low- (A), intermediate- (B), and high- (C) power images of MALT lymphoma arising in the breast. More about this image found in EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MAL...
Images
Figure 24-17

POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross ...

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in Cardiac Transplantation > Disorders of the Heart and Blood Vessels
Published: 15 November 2023
POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) Figure 24-17 POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross nodules can be seen involving an extranodal site (liver, in this case). B: PTLD may appear as infiltrating collections of plump lymphocytes and plasma cells More about this image found in POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross ...
Book Chapter

Rare Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
..., atypical cells. D: A keratin stain is negative in the malignant cells. The constellation of findings is consistent with a diagnosis of DLBCL. EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA) Figure 12-4 EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID...
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Book Chapter

Inflammatory and Reactive Conditions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... . Breast involvement by extranodal Rosai-Dorfman disease: report of seven cases . Am J Surg Pathol   1997 ; 21 : 664 - 8 . 20. Tenny   SO , McGinness   M , Zhang   D , Damjanov   I , Fan   F . Rosai-Dorfman disease presenting as a breast mass and enlarged axillary lymph node...
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Book Chapter

Axillary Lymph Nodes

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
.../cp-breast-invasive-resection-20-4400.pdf . 3. Mamtani   A , Barrio   AV , Goldman   DA , Wen   HY , Vincent   A , Morrow   M . Extranodal tumor deposits in the axillary fat indicate the need for axillary dissection among T1-T2cN0 patients with positive sentinel nodes . Ann...
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Book Chapter

Cardiac Lymphomas and Histiocytic Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch57
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... Res   2016 ; 5 : 1 - 5 . 82. Maleszewski   JJ , Hristov   AC , Halushka   MK , Miller   DV . Extranodal Rosai-Dorfman disease involving the heart: report of two cases . Cardiovasc Pathol   2010 ; 19 : 380 - 4 . 83. Yontz   L , Franco   A , Sharma   S , Lewis   K...
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Book Chapter

Cardiac Transplantation

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... pathogen (black arrow). POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) Figure 24-17 POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) A: Two discrete gross nodules can be seen involving an extranodal site (liver, in this case). B: PTLD may appear as infiltrating collections of plump lymphocytes...
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Book Chapter

Arrhythmias and Conduction System Disease

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch25
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... or as an extension of annular calcification. Extranodal Atrioventricular Connections. Historically termed “Mahaim fibers,” connections of cardiomyocytes between the atrium and ventricle as seen in sections of the AV nodal area have been implicated in sudden death, presumably by causing re-entry circuit rhythms...
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