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Figure 8-32

PIGMENTED PHEOCHROMOCYTOMA The accumulation of melanin in the tumor cells ...

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in Pheochromocytoma and Adrenal Medullary Hyperplasia > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PIGMENTED PHEOCHROMOCYTOMA Figure 8-32 PIGMENTED PHEOCHROMOCYTOMA The accumulation of melanin in the tumor cells can mimic melanoma and these tumors can appear black on gross examination. More about this image found in PIGMENTED PHEOCHROMOCYTOMA The accumulation of melanin in the tumor cells ...
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Figure 8-49

PHEOCHROMOCYTOMA: ATYPICAL MITOSES A–C: The presence of atypical mitoses s...

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in Pheochromocytoma and Adrenal Medullary Hyperplasia > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA: ATYPICAL MITOSES Figure 8-49 PHEOCHROMOCYTOMA: ATYPICAL MITOSES A–C: The presence of atypical mitoses should prompt careful examination for other features suggestive of aggressive behavior. More about this image found in PHEOCHROMOCYTOMA: ATYPICAL MITOSES A–C: The presence of atypical mitoses s...
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Figure 11-5

METAIODOBENZYLGUANIDINE (MIBG) SCAN OF WIDELY METASTASIZED NEUROBLASTOMA A...

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in Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ultrasound was suspicious of a renal tumor. After referral to an expert center, clinical examination (slight hypertension), laboratory testing (increased urinary catecholamines), and abdominal MRI imaging showed that a diagnosis of metastatic NB was more likely. The MRI depicted a right-sided adrenal mass More about this image found in METAIODOBENZYLGUANIDINE (MIBG) SCAN OF WIDELY METASTASIZED NEUROBLASTOMA A...
Book Chapter

Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). As stated in chapter 1 , careful gross dissection of the adrenal glands, with removal of all periadrenal connective tissue and fat, is necessary for the accurate determination of the size and weight of the gland. Small nodules may not be apparent on external examination of the intact gland, and, therefore...
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Book Chapter

Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...) SCAN OF WIDELY METASTASIZED NEUROBLASTOMA A 2-year old girl presented with fever and a painless swelling in the abdomen. Blood and urine cultures were negative and initial ultrasound was suspicious of a renal tumor. After referral to an expert center, clinical examination (slight hypertension...
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Book Chapter

Pheochromocytoma and Adrenal Medullary Hyperplasia

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., and at autopsy, performed by Professor Rudolf Maier, was found to have bilateral adrenal tumors that had a specific brown appearance after exposure to chromate-containing Mueller fixative. These tumors were examined histologically by Professor Max Schottelius who provided an elegant microscopic description...
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Figure 25-2

TOXOPLASMA CHORIORETINITIS Fundoscopic examination shows ...

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in Central Nervous System > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
TOXOPLASMA CHORIORETINITIS Figure 25-2 TOXOPLASMA CHORIORETINITIS Fundoscopic examination shows active lesions, scarring, and choroidal neovascularization. (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL]) More about this image found in TOXOPLASMA CHORIORETINITIS Fundoscopic examination shows ...
Book Chapter

Adrenal Cortical Adenoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... They show a female predominance and are nonfunctioning in more than 50 percent of cases ( 32 ). In one study of nonfunctioning cases, there was no expression of the enzymes involved in steroidogenesis that were examined ( 33 ). Hormonally active tumors more frequently secrete cortisol or sex steroid...
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Figure 3-8

NEUROPATHIC FLAVIVIRUS DISEASE PREVENTION Inspector examining discarded ti...

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in Central Nervous System > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
NEUROPATHIC FLAVIVIRUS DISEASE PREVENTION Figure 3-8 NEUROPATHIC FLAVIVIRUS DISEASE PREVENTION Inspector examining discarded tires, where stagnant water frequently collects and serves as a breeding place for mosquitos. (Courtesy of the CDC PHIL) More about this image found in NEUROPATHIC FLAVIVIRUS DISEASE PREVENTION Inspector examining discarded ti...
Book Chapter

Adrenal Cortical Carcinoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... that preclude accurate assessment of the tumor capsule and with a higher risk of positive resection margins ( 120 ). On external examination and in cross section, ACC often has a coarsely lobulated appearance, with soft, bulging nodules ranging from yellow-orange to tan. The color is determined by the relative...
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Book Chapter

Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ), but in many instances diagnosis is by fine needle aspiration biopsy or examination of surgically resected specimens. Nonendocrine adrenal lesions are now most often discovered as incidentalomas, defined as masses larger than 1 cm detected during imaging for unrelated conditions. The strictest definition...
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Book Chapter

Congenital Disorders of the Adrenal Gland

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., pseudoinclusions are often seen. Cortical microcysts may be present in the adult cortex on histologic examination. Rarely, gross hemorrhagic macrocysts of the adrenal cortex present as an abdominal mass in the fetus and neonate with BWS ( 62 ). Chromaffin cells may be strikingly hyperplastic within adrenal ( fig...
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Book Chapter

Paraganglia and Paragangliomas

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... a metastasis, the primary should be examined for morphologic and immunohistochemical comparison. This is often not possible, however. The absence of sustentacular cells is helpful in some cases ( 106 ), but rare sustentacular cells are found in bona fide metastases ( 124 ). In addition, other cell types...
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Images
Figure 22-9

ESOPHAGEAL CANDIDIASIS These fungal organisms were only identified after c...

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in Gastrointestinal Tract > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
ESOPHAGEAL CANDIDIASIS Figure 22-9 ESOPHAGEAL CANDIDIASIS These fungal organisms were only identified after careful examination of numerous PAS-stained levels, due to their scant and focal nature. More about this image found in ESOPHAGEAL CANDIDIASIS These fungal organisms were only identified after c...
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Figure 16-2

INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic ...

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in Heart > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
INFECTIVE ENDOCARDITIS Figure 16-2 INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic examination. Note the round to flame-shaped retinal hemorrhage with pale center (arrow). (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library More about this image found in INFECTIVE ENDOCARDITIS Ocular involvement shows Roth spots on fundoscopic ...
Book Chapter

Skin and Soft Tissue

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Muscular sarcocystosis is also most frequently asymptomatic and usually diagnosed incidentally when muscle is examined histopathologically for another indication. Symptoms, which usually present between 1 and 2 weeks after human sporocyst ingestion, are fever, fatigue, weakness, headache, myalgia...
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Gastrointestinal Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... distribution of numerous fungal organisms in the ulcer floor (B), present mainly in yeast form (C) (A–C: PAS-d stain). ESOPHAGEAL CANDIDIASIS Figure 22-9 ESOPHAGEAL CANDIDIASIS These fungal organisms were only identified after careful examination of numerous PAS-stained levels, due to their scant and focal...
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Book Chapter

Heart

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of choice. Examination for T. cruzi trypomastigotes in blood or cerebrospinal fluid is performed on Wright- or Giemsa-stained smears. The trypomastigotes are extracellular, C- or S-shaped unicellular organisms with an undulating membrane on one side of the parasite, and a prominent kinetoplast...
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Book Chapter

Central Nervous System

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Usually unilateral Pain, conjunctival hyperemia, foreign body sensation, excessive lacrimation, and photophobia On examination, ring-shaped inflammatory infiltrate is characteristic If untreated, may lead to corneal ulceration and blindness Herpes simplex virus keratitis Skin infection...
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Book Chapter

Liver and Gastrointestinal Tract

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... biopsy material (see fig. 26-38 ). Jejunal aspirates, stool concentration techniques, and examination of multiple stool samples increase the diagnostic yield if the organism burden is low ( 55 ). Oocysts have different tinctorial properties than intracellular forms of the parasite, and can be identified...
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