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METASTATIC BREAST CARCINOMA TO COLON  A: Low-power <span class="search-highlight">examination</span> reveals grea...
Published: 01 January 2024
METASTATIC BREAST CARCINOMA TO COLON Figure 8-71 METASTATIC BREAST CARCINOMA TO COLON A: Low-power examination reveals greater cellularity in the lamina propria than is typical. B: On higher-power examination, single atypical epithelial cells and glands are identified. C: An ER stain supports t... More about this image found in METASTATIC BREAST CARCINOMA TO COLON A: Low-power examination reveals grea...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... (junctional hyperplasia or melanocytic nevus) by examining PRAME (preferentially expressed antigen in melanoma) expression. Strong diffuse labeling of most melanocytes favors melanoma ( 18 ). However, approximately 10 percent of LMs are negative for PRAME, isolated rare melanocytes of chronically sun-damaged...
Images
NIPPLE MARGIN  This low-power image illustrates a shaved, en face section o...
Published: 01 January 2024
NIPPLE MARGIN Figure 15-11 NIPPLE MARGIN This low-power image illustrates a shaved, en face section of the nipple margin. This orientation permits examination of a cross-section of the nipple ducts. More about this image found in NIPPLE MARGIN This low-power image illustrates a shaved, en face section o...
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CARDIAC LIPOMA  Surgically resected cardiac lipoma on external <span class="search-highlight">examination</span> ...
Published: 15 November 2023
CARDIAC LIPOMA Figure 46-3 CARDIAC LIPOMA Surgically resected cardiac lipoma on external examination (left) and on cut section (right), shows a well-circumscribed uniform yellow fatty mass without hemorrhage or necrosis. More about this image found in CARDIAC LIPOMA Surgically resected cardiac lipoma on external examination ...
Images
NODULAR ADENOSIS  A: At scanning magnification, a large, relatively circums...
Published: 01 January 2024
NODULAR ADENOSIS Figure 6-8 NODULAR ADENOSIS A: At scanning magnification, a large, relatively circumscribed collection of small glands is apparent. B: Higher-power examination reveals the characteristic features of sclerosing adenosis. Mass-forming lesions such as this are referred to as nodula... More about this image found in NODULAR ADENOSIS A: At scanning magnification, a large, relatively circums...
Images
INVASIVE LOBULAR CARCINOMA  A: At low power, invasive lobular carcinoma wit...
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA Figure 8-35 INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma with low nuclear grade can resemble chronic inflammation. B: Higher-power examination reveals the epithelial nature of the cells as well as the characteristic cytologic features. More about this image found in INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma wit...
Images
MYXOID FIBROADENOMA MIMICKING MUCINOUS CARCINOMA  A: At higher power, a sin...
Published: 01 January 2024
MYXOID FIBROADENOMA MIMICKING MUCINOUS CARCINOMA Figure 5-20 MYXOID FIBROADENOMA MIMICKING MUCINOUS CARCINOMA A: At higher power, a single gland present in a myxoid background has the potential to be misinterpreted as hypocellular mucinous carcinoma. B: Low-power examination permits appreciation... More about this image found in MYXOID FIBROADENOMA MIMICKING MUCINOUS CARCINOMA A: At higher power, a sin...
Images
COMPLEX SCLEROSING LESION  A: It is difficult to recognize the underlying c...
Published: 01 January 2024
COMPLEX SCLEROSING LESION Figure 6-32 COMPLEX SCLEROSING LESION A: It is difficult to recognize the underlying complex sclerosing lesion. In this case, there are small angular glands entrapped in a dense hyalinized stroma. B: Higher-power examination reveals the absence of any epithelial atypia.... More about this image found in COMPLEX SCLEROSING LESION A: It is difficult to recognize the underlying c...
Images
PHYLLODES TUMOR  The cut surface of this benign phyllodes tumor demonstrate...
Published: 01 January 2024
PHYLLODES TUMOR Figure 5-21 PHYLLODES TUMOR The cut surface of this benign phyllodes tumor demonstrates a well-circumscribed, lobulated tumor. The tumor appears to bulge forth and there are grooves in the cut surface that correspond to the elongated ducts and slit-like spaces seen on microscopic ... More about this image found in PHYLLODES TUMOR The cut surface of this benign phyllodes tumor demonstrate...
Images
SOLID BASALOID ADENOID CYSTIC CARCINOMA  A: On low power, this tumor has a ...
Published: 01 January 2024
SOLID BASALOID ADENOID CYSTIC CARCINOMA Figure 8-68 SOLID BASALOID ADENOID CYSTIC CARCINOMA A: On low power, this tumor has a very basaloid (and solid) appearance. B: Careful examination at high power reveals areas of basement membrane material and more spindled myoepithelial cell nuclei. C: A ... More about this image found in SOLID BASALOID ADENOID CYSTIC CARCINOMA A: On low power, this tumor has a ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...As with any field in pathology, appropriate specimen processing is critical to tissue evaluation. Breast tissue, in particular, due to its inherently fatty composition requires special attention to adequate fixation prior to processing in order to ensure optimal microscopic examination and accuracy...
Images
DUCTAL CARCINOMA IN SITU WITH MICROINVASION  A: At low power, a portion of ...
Published: 01 January 2024
DUCTAL CARCINOMA IN SITU WITH MICROINVASION Figure 8-25 DUCTAL CARCINOMA IN SITU WITH MICROINVASION A: At low power, a portion of a field of extensive high nuclear grade DCIS with desmoplasia and stromal inflammation is seen. Microinvasion can be difficult to identify in cases of this type. B,C:... More about this image found in DUCTAL CARCINOMA IN SITU WITH MICROINVASION A: At low power, a portion of ...
Images
SENTINEL LYMPH NODE STATUS POSTNEOADJUVANT SYSTEMIC CHEMOTHERAPY  A: At int...
Published: 01 January 2024
SENTINEL LYMPH NODE STATUS POSTNEOADJUVANT SYSTEMIC CHEMOTHERAPY Figure 14-10 SENTINEL LYMPH NODE STATUS POSTNEOADJUVANT SYSTEMIC CHEMOTHERAPY A: At intermediate power, this lymph node is replaced by fibrosis characteristic of treatment effect. Careful examination in the areas of fibrosis reveals... More about this image found in SENTINEL LYMPH NODE STATUS POSTNEOADJUVANT SYSTEMIC CHEMOTHERAPY A: At int...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-01
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... be missed, unless several levels are examined. The detection of a melanocyte nest is the key finding in the distinction of a junctional nevus and a lentigo simplex. It is rare for a lentigo simplex to be mistaken for melanoma in situ, but it can happen. With only a small partial biopsy available for review...
Images
BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA (BIA-ALCL)  A: Low...
Published: 01 January 2024
BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA (BIA-ALCL) Figure 12-5 BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA (BIA-ALCL) A: Low-power image of a cell block preparation from a fluid collection that had accumulated around a breast implant. The specimen is highly cellular,... More about this image found in BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA (BIA-ALCL) A: Low...
Images
INVASIVE PAGET DISEASE  A: A low-power image of the nipple shows malignant ...
Published: 01 January 2024
INVASIVE PAGET DISEASE Figure 13-17 INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant epithelial cells predominantly at the basal aspect of the epidermis, with overlying erosion and associated exudate. There is a brisk inflammatory cell infiltrate at the dermoepidermal jun... More about this image found in INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant ...
Images
INVASIVE PAGET DISEASE  A: A low-power image of the nipple shows malignant ...
Published: 01 January 2024
INVASIVE PAGET DISEASE Figure 13-17 INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant epithelial cells predominantly at the basal aspect of the epidermis, with overlying erosion and associated exudate. There is a brisk inflammatory cell infiltrate at the dermoepidermal jun... More about this image found in INVASIVE PAGET DISEASE A: A low-power image of the nipple shows malignant ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., from skin-colored to various shades of brown or red. On dermoscopic examination, the intradermal nests give the lesion a granular or globular appearance ( 7 ). MICROANATOMIC ORIGIN OF MELANOCYTIC NEVI In 1893, Unna suggested that epidermal melanocytes were the source of acquired nevi ( 8 , 9...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-15
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... examinations. While nodular melanomas tend to present at a higher pathologic stage, after adjustment for stage, they have a prognosis comparable to other melanoma types. They are surgically managed like any other invasive melanoma, but one could argue that tumors with a circumscribed nodular growth pattern...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... is defined as a cutaneous or subcutaneous tumor deposit adjacent or deep to a primary melanoma recognized on microscopic examination of the primary tumor excision. It must clearly be discontinuous from the primary tumor and not be embedded in a scar or inflammation that is incontinuity with the primary tumor...