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epithelioid

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Pigmented epithelioid melanocytoma (PEM) is a heavily pigmented melanocytic tumor composed of large epithelioid, fusiform, and dendritic melanocytes admixed with macrophages ( 1 , 2 ). Prior to the introduction of the term PEM, tumors with similar features were reported as “animal-type...
Images
PIGMENTED <span class="search-highlight">EPITHELIOID</span> MELANOCYTOMA  The nuclei of the <span class="search-highlight">epithelioid</span> melanocyt...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-3 PIGMENTED EPITHELIOID MELANOCYTOMA The nuclei of the epithelioid melanocytes (arrows) are round to oval, with a vesicular chromatin pattern. Melanophages (*) with coarse melanin pigment are also present. More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA The nuclei of the epithelioid melanocyt...
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MATURATION OF A CMN  <span class="search-highlight">Epithelioid</span> melanocytes, some of them pigmented, are a...
Published: 01 February 2024
MATURATION OF A CMN Figure 2-7 MATURATION OF A CMN Epithelioid melanocytes, some of them pigmented, are arranged in nests in the superficial dermis. With descent into the mid and deep dermis, melanocytes become smaller and splay into fibrous stroma as solitary units. More about this image found in MATURATION OF A CMN Epithelioid melanocytes, some of them pigmented, are a...
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CMN WITH PIGMENTED EPITHELIOCYTOMA/<span class="search-highlight">EPITHELIOID</span> BLUE NEVUS-LIKE PN  A: Low-p...
Published: 01 February 2024
CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN Figure 2-18 CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-power view of a portion of a giant CMN that contains a pigmented nodule. B: The pigmented nodule is composed of large epithelioid melanocytes and... More about this image found in CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-p...
Images
FEATURES OF MATURATION  A: <span class="search-highlight">Epithelioid</span> (type A) melanocytes with pink cytop...
Published: 01 February 2024
FEATURES OF MATURATION Figure 3-9 FEATURES OF MATURATION A: Epithelioid (type A) melanocytes with pink cytoplasm arranged in nests tend to be located in the superficial dermis of a nevus. B: With descent into the mid dermis, type B melanocytes may display lymphocyte-like features characterized b... More about this image found in FEATURES OF MATURATION A: Epithelioid (type A) melanocytes with pink cytop...
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BLUE NEVUS WITH <span class="search-highlight">EPITHELIOID</span> CELL FEATURES  A: Heavily pigmented intradermal...
Published: 01 February 2024
BLUE NEVUS WITH EPITHELIOID CELL FEATURES Figure 8-10 BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal melanocytic nevus. B,C: Most of the pigmented tumor cells are epithelioid in appearance. A minor population of melanocytes displays conventional BN-like fusiform and d... More about this image found in BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal...
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DEEP PENETRATING NEVUS  Nests of pigmented spindle and <span class="search-highlight">epithelioid</span> melanocy...
Published: 01 February 2024
DEEP PENETRATING NEVUS Figure 9-7 DEEP PENETRATING NEVUS Nests of pigmented spindle and epithelioid melanocytes are surrounded by bipolar spindle cells (arrows). This feature has been referred to as “ball in mitt.” Multinucleated cells (arrowhead) are also present. More about this image found in DEEP PENETRATING NEVUS Nests of pigmented spindle and epithelioid melanocy...
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COMBINED PIGMENTED <span class="search-highlight">EPITHELIOID</span> MELANOCYTOMA  The predominant cell populatio...
Published: 01 February 2024
COMBINED PIGMENTED EPITHELIOID MELANOCYTOMA Figure 10-15 COMBINED PIGMENTED EPITHELIOID MELANOCYTOMA The predominant cell population of this biphenotypic melanocytic neoplasm shows features of a pigmented epithelioid melanocytoma (*). A minor cell population shows conventional nevus features (arr... More about this image found in COMBINED PIGMENTED EPITHELIOID MELANOCYTOMA The predominant cell populatio...
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PIGMENTED <span class="search-highlight">EPITHELIOID</span> MELANOCYTOMA  A: Scanning magnification of a lesion f...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-1 PIGMENTED EPITHELIOID MELANOCYTOMA A: Scanning magnification of a lesion from the back of a 17-year-old girl shows a heavily and uniformly pigmented, symmetrical, circumscribed and predominantly intradermal tumor. B: Many of the tumor cells have lar... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Scanning magnification of a lesion f...
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PIGMENTED <span class="search-highlight">EPITHELIOID</span> MELANOCYTOMA  A: Silhouette of a heavily pigmented in...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-2 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented intradermal tumor from the shoulder of a 15-year-old boy. B: Junctional melanocytes are present, and many tumor cells involve both the papillary and reticular dermis. There is a... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented in...
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PIGMENTED <span class="search-highlight">EPITHELIOID</span> MELANOCYTOMA  A: Silhouette of a heavily pigmented co...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-4 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented compound tumor from the back of a 22-year-old male. There is associated epidermal hyperplasia. B: Epithelioid to ovoid cells are present, with a vesicular chromatin pattern and ... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented co...
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COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS  A: Silhouette of a predominant...
Published: 01 February 2024
COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS Figure 10-7 COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS A: Silhouette of a predominantly intradermal melanocytic nevus. A nodular proliferation of large epithelioid melanocytes (*) in the center of the lesion is flanked by a plaque-like growth of conven... More about this image found in COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS A: Silhouette of a predominant...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... penetrating nevus ( 5 ), or large (pigmented or amelanotic) epithelioid cell nevus ( 6 – 8 ). Conventional acquired or congenital nevi are also associated with a second melanocyte population displaying spitzoid ( 9 ), balloon cell, Clark, neurotized, and/or desmoplastic features or pigmented epithelioid...
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MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS  A: A nodule of epithelio...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS Figure 18-1 MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelioid melanocytes is associated with melanophages as well as pigmented slender and dendritic melanocytes in the surrounding dermis. B,C: The epithelioid melanocytes display nuclear atypia (B) and lack nuclear expression of BAP1 (C), which is retained in melanophages and stromal cells. D: The epithelioid melanocytes diffusely express PRAME (preferentially expressed antigen in melanoma). The tumor carried a GNAQ 209L mutation. More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelio...
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COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS  A: Silhouette of a predominant...
Published: 01 February 2024
COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS Figure 10-8 COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS A: Silhouette of a predominantly intradermal melanocytic nevus. B: There is a dual population of melanocytes with small conventional melanocytes present at the periphery of the lesion (thin arrow)... More about this image found in COMBINED BAP1-INACTIVATED MELANOCYTIC NEVUS A: Silhouette of a predominant...
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COMBINED DEEP PENETRATING NEVUS  This compound melanocytic nevus is predomi...
Published: 01 February 2024
COMBINED DEEP PENETRATING NEVUS Figure 10-5 COMBINED DEEP PENETRATING NEVUS This compound melanocytic nevus is predominantly composed of conventional small epithelioid melanocytes (arrow), a minor subpopulation of pigmented spindle and epithelioid melanocytes (*), and clusters of melanophages. More about this image found in COMBINED DEEP PENETRATING NEVUS This compound melanocytic nevus is predomi...
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COMBINED INVERTED TYPE A NEVUS  A: Silhouette of an intradermal melanocytic...
Published: 01 February 2024
COMBINED INVERTED TYPE A NEVUS Figure 10-6 COMBINED INVERTED TYPE A NEVUS A: Silhouette of an intradermal melanocytic nevus with variable pigmentation. B: Most of the nevus cells display small conventional epithelioid cell features (arrow), but there is a minor subpopulation of larger pigmented ... More about this image found in COMBINED INVERTED TYPE A NEVUS A: Silhouette of an intradermal melanocytic...
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COMBINED BLUE NEVUS  A: Intradermal melanocytic nevus with a superficial de...
Published: 01 February 2024
COMBINED BLUE NEVUS Figure 10-10 COMBINED BLUE NEVUS A: Intradermal melanocytic nevus with a superficial dermal population of small epithelioid melanocytes (arrow) overlying a proliferation of pigmented fusiform and dendritic cells (*). B: Juxtaposition of conventional small epithelioid melanocy... More about this image found in COMBINED BLUE NEVUS A: Intradermal melanocytic nevus with a superficial de...