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epithelioid
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Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PRIMARY ADRENAL ANGIOSARCOMA Figure 12-10 PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative architecture with sinusoidal growth between cords of vacuolated cortical cells. Acute inflammatory cells and eosinophils are also present. B: Primary adrenal angiosarcoma (same case as... More about this image found in PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative arch...
Images
in Other Adrenal Neoplasms and Tumor-Like Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Figure 12-17 MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Interlacing fascicles of spindle cells and epithelioid cells are present beneath a small area of residual adrenal cortex. More about this image found in MALIGNANT PERIPHERAL NERVE SHEATH TUMOR Interlacing fascicles of spindle c...
Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A Figure 8-61 NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adrenal medulla is diffusely thickened and contains multiple nodules. B: At higher magnification there are three nodules that can be distinguished based ... More about this image found in NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adren...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... angiosarcoma usually presents little difficulty in diagnosis when there is a clear vasoformative pattern ( fig. 12-10A ). Problems arise with tumors having a solid pattern composed of epithelioid or spindle cells (seen focally in fig. 12-10B and to a greater extent in fig. 12-10C ). For these tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... tissues. Most cases histologically show a biphasic morphology, with an epithelioid component consistent with a conventional ACC admixed to a variable extent with an often predominant sarcomatoid pattern, characterized by spindle cell architecture and highly pleomorphic cells ( 145 ). When monophasic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... , Coplan KA , et al . Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors . Am J Surg Pathol 1998 ; 22 : 57 - 63 . 52. Mete O , van der Kwast TH . Epithelioid angiomyolipoma: a morphologically distinct variant that mimics...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... eosinophilic cells, the middle small nodule is composed of basophilic large cells, and the nodule on the right has a slightly more epithelioid appearance. The histologic appearance of adrenal medullary hyperplasia is variable. The enlarged medulla may have the microscopic appearance of normal medulla...
Images
Published: 01 September 2024
DISSEMINATED TUBERCULOSIS TO LIVER Figure 12-61 DISSEMINATED TUBERCULOSIS TO LIVER A small epithelioid cell granuloma (A) and numerous scattered acid-fast bacilli (B). More about this image found in DISSEMINATED TUBERCULOSIS TO LIVER A small epithelioid cell granuloma (A) ...
Images
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-19 TUBERCULOID LEPROSY Periadnexal epithelioid cell and focally granulomatous infiltrate. More about this image found in TUBERCULOID LEPROSY Periadnexal epithelioid cell and focally granulomatous...
Images
Published: 01 September 2024
PARACOCCIDIOIDOMYCOSIS Figure 21-17 PARACOCCIDIOIDOMYCOSIS A: Well-formed epithelioid cell granulomas with associated multinucleated giant cells and surrounding lymphocyte infiltrate. (Both: courtesy of G. Varela, Hospital Pablo Tobón Uribe, Medellín, Columbia) B: Weakly refractive round to oval Paracoccidioides yeasts (arrow) can be visualized in the granulomas on a routine H&E stain. More about this image found in PARACOCCIDIOIDOMYCOSIS A: Well-formed epithelioid cell granulomas with ass...
Images
Published: 01 September 2024
CUTANEOUS LEISHMANIASIS Figure 28-6 CUTANEOUS LEISHMANIASIS Cutaneous epithelioid cell granulomas have giant cells and a rim of lymphocytes. Giant cell intracytoplasmic parasites are abundant. (Courtesy of the Armed Forces Institute of Pathology) More about this image found in CUTANEOUS LEISHMANIASIS Cutaneous epithelioid cell granulomas have giant c...
Images
Published: 01 September 2024
TUBERCULOUS GRANULOMA Figure 12-51 TUBERCULOUS GRANULOMA Central fibrillogranular (caseous) necrosis with surrounding palisaded epithelioid histiocytes. More about this image found in TUBERCULOUS GRANULOMA Central fibrillogranular (caseous) necrosis with sur...
Images
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-17 TUBERCULOID LEPROSY There is a prominent perineural lymphocyte and epithelioid histiocyte infiltrate. (Courtesy of Dr. L. Tapia V, University of Antioquia, Medellín, Colombia) More about this image found in TUBERCULOID LEPROSY There is a prominent perineural lymphocyte and epithel...
Images
Published: 01 September 2024
LYMPHOGRANULOMA VENEREUM Figure 18-16 LYMPHOGRANULOMA VENEREUM Low-power appearance of lymph node involvement demonstrates characteristic geographic to stellate necrosis, surrounding palisaded epithelioid cells, and a paucity of multinucleated giant cells. (Courtesy of the AFIP Archives) More about this image found in LYMPHOGRANULOMA VENEREUM Low-power appearance of lymph node involvement de...
Images
Published: 01 September 2024
YERSINIA APPENDICITIS Figure 13-12 YERSINIA APPENDICITIS A–C: Yersinia enterocolitica infection, showing lymphoid hyperplasia (A) and focal germinal center neutrophil infiltration with early microabscess formation (B, arrow; C) are seen. D,E: Y. pseudotuberculosis appendix involvement demonstrates lymphoid hyperplasia and epithelioid cell granuloma formation in relation to germinal centers. (Courtesy of Dr. L. W. Lamps, University of Michigan, Ann Arbor, MI) More about this image found in YERSINIA APPENDICITIS A–C: Yersinia enterocolitic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of yeasts, which are phagocytosed and may then remain dormant in alveolar and lymph node macrophages, as well as epithelioid granulomas. Several factors allow cryptococci to replicate without causing cell lysis, including their ability to grow at a high (body) temperature (37°C). The fungal polysaccharide...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... response, number of parasitic organisms, and extent of disease dissemination ( fig. 28-4 ). The disease is similar to leprosy in that the spectrum of histologic findings ranges from a striking granulomatous response with abundant well-formed epithelioid cell granulomas and minimal associated parasites...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is necrotizing granulomatous inflammation, which is most striking in the lung. The prototypical granuloma has a trizonal appearance, with peripheral fibrosis, an adjacent layer of epithelioid and multinucleated giant cells, and central fibrillogranular (caseous) necrosis ( fig. 23-4 ). In contrast...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) ( 34 ). Table 15-7 HISTOPATHOLOGIC FEATURES ASSOCIATED WITH THE DIFFERENT PRESENTATIONS OF LEPROSY Features Indeterminate Tuberculoid Borderline Tuberculoid Borderline Borderline Lepromatous Lepromatous Inflammatory cells Lymphocytes Epithelioid histiocytes Lymphocytes Epithelioid...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... A LYMPH NODE Figure 18-7 SECONDARY SYPHILIS INVOLVING A LYMPH NODE Endothelial cell swelling, plasma cell infiltration (A), and early granuloma formation (B). Tertiary syphilis is characterized by gummas, loose granulomas consisting of lymphocytes, epithelioid cells, and isolated multinucleated giant...
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