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Figure 8-22
Published: 01 December 2024
PHEOCHROMOCYTOMA Figure 8-22 PHEOCHROMOCYTOMA The tumor cells are round and regular, with abundant cytoplasm, resembling cells of an epithelial neuroendocrine tumor. More about this image found in PHEOCHROMOCYTOMA The tumor cells are round and regular, with abundant cyto...
Images
Figure 9-33
Published: 01 December 2024
DUODENAL PARAGANGLIOMA Figure 9-33 DUODENAL PARAGANGLIOMA A: This tumor was initially interpreted as an epithelial intestinal NET. However, it was negative for keratins and expressed paraganglioma markers. The absence of keratins also weighed against a diagnosis of composite gangliocytoma More about this image found in DUODENAL PARAGANGLIOMA A: This tumor was initially interpreted as an epith...
Images
Figure 9-32
Published: 01 December 2024
PULMONARY PARAGANGLIOMA Figure 9-32 PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initially interpreted as an epithelial pulmonary NET. The patient was found to have a hereditary SDHC mutation. No other primary tumors were found and this tumor contained abundant More about this image found in PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initia...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the differential diagnosis is between a normal paraganglion and an epithelial tumor deposit. This is a concern in the genitourinary tract where normal paraganglia may be mistaken for prostatic ( 13 ) or urothelial cancer because of their often clear cytoplasm (see fig. 9-6 ). PARAGANGLIOMAS Paragangliomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... are categorized according to the presence or absence of a lining and the type of lining identified. The categories are epithelial cysts, endothelial cysts, pseudocysts, and parasitic cysts. Endothelial cysts are further divided into angiomatous and lymphangiomatous types ( 81 ). While this system may have use...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... granular basophilic cytoplasm and indistinct cell borders ( fig. 8-20 ) or they may be lightly eosinophilic ( fig. 8-21 ). Occasionally, they are round with chromophobic or amphophilic cytoplasm, and can be mistaken for an epithelial neuroendocrine tumor ( fig. 8-22 ). They may have elongated processes...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... were also identified in the unusual duodenal lesion known as gangliocytic paraganglioma ( 87 ), not as part of the syndrome; these are not considered to be true paragangliomas but rather are triphasic tumors composed of epithelial neuroendocrine cells, ganglion cells, and neural stroma ( 88 ). Carney...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... SYNDROMES BRCA1 and BRCA2 syndromes are caused by germline mutations in the BRCA1 and BRCA2 tumor suppressor genes, respectively, which result in a significant increase in the likelihood of developing particular types of epithelial malignancies, namely breast, ovarian...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Adrenal cortical carcinoma (ACC) is a malignant neoplasm originating from the steroidogenic epithelial cells of the adrenal cortex. EPIDEMIOLOGY ACC accounts for the majority of deaths attributable to primary adrenal neoplasia, but it is a rare disease, meeting the criteria for an “orphan...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... markers for lymphoblastic lymphoma, WT1 for Wilms tumor, and possibly epithelial membrane antigen (EMA), keratins, and WT1 (C-terminus) for desmoplastic small round cell tumor. The second application for immunohistochemistry in the workup of NBL and GNBL is in the detection of minimal residual disease...
Images
Figure 8-12
Published: 01 September 2024
NASOPHARYNGEAL CARCINOMA Figure 8-12 NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encoded small RNA (EBER) in situ hybridization (ISH), confirming the EBV association of the tumor. More about this image found in NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encod...
Images
Images
Figure 9-46
Published: 01 September 2024
DECOY CELLS Figure 9-46 DECOY CELLS High-power view of renal tubule, showing BKV epithelial nuclear inclusions with numerous “decoy cells.” (Courtesy of Dr. L. F. Arias, University of Antioquia, Medellín, Colombia) More about this image found in DECOY CELLS High-power view of renal tubule, showing BKV epithelial nuclea...
Images
Figure 26-25
Published: 01 September 2024
COLONIC CRYPTOSPORIDIOSIS Figure 26-25 COLONIC CRYPTOSPORIDIOSIS Colonic cryptosporidiosis showing associated nonspecific reactive epithelial changes. More about this image found in COLONIC CRYPTOSPORIDIOSIS Colonic cryptosporidiosis showing associated non...
Images
Figure 30-7
Published: 01 September 2024
TRICHOMONAS Figure 30-7 TRICHOMONAS Wet mount of cervical specimen shows numerous trophozoites in relation to squamous epithelial cells. (Courtesy of the CDC PHIL) More about this image found in TRICHOMONAS Wet mount of cervical specimen shows numerous...
Images
Figure 4-2
Published: 01 September 2024
INFLUENZA INFECTION OF THE LUNG Figure 4-2 INFLUENZA INFECTION OF THE LUNG Prominent congestion (A), lymphocyte infiltration, epithelial necrosis, and extensive submucosal hemorrhages (B) are seen. More about this image found in INFLUENZA INFECTION OF THE LUNG Prominent congestion (A), lymphocyte infil...
Images
Figure 8-11
Published: 01 September 2024
EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Figure 8-11 EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associated lymphocyte infiltrate (B), with pancytokeratin immunohistochemistry (C) confirm the epithelial nature of the neoplasm. More about this image found in EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associ...
Images
Figure 26-33
Published: 01 September 2024
DUODENAL CYSTOISOSPORIASIS Figure 26-33 DUODENAL CYSTOISOSPORIASIS Associated nonspecific histologic features: villous attenuation, an increase in lamina propria chronic inflammatory cells, and focal superficial epithelial disarray (A,B). More about this image found in DUODENAL CYSTOISOSPORIASIS Associated nonspecific histologic features: vil...
Images
Figure 4-30
Published: 01 September 2024
MEASLES VIRUS Figure 4-30 MEASLES VIRUS MeV infection of the lung at high power shows a multinucleated epithelial giant cell with eosinophilic intracytoplasmic and focal intranuclear inclusions. (Courtesy of the CDC IDPB) More about this image found in MEASLES VIRUS MeV infection of the lung at high power shows a multinucleat...
Images
Figure 9-47
Published: 01 September 2024
BKV NEPHROPATHY Figure 9-47 BKV NEPHROPATHY Anti-SV40 immunohistochemical stain reveals extensive epithelial nuclear positivity. (Courtesy of Dr. L. F. Arias, University of Antioquia, Medellín, Colombia) More about this image found in BKV NEPHROPATHY Anti-SV40 immunohistochemical stain reveals extensive epit...