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1-20 of 273 Search Results for
endocrine
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Images
in Hereditary Predisposition to Adrenal Cortical Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MULTIPLE ENDOCRINE NEOPLASIA 1 (MEN1) Figure 7-4 ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MULTIPLE ENDOCRINE NEOPLASIA 1 (MEN1) Transverse sections of adrenal gland with micro- and macronodular nodular disease. The pale yellow cortical ... More about this image found in ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MULTIPLE ENDOCRINE NEOPL...
Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
MULTIFOCAL PHEOCHROMOCYTOMA ASSOCIATED WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) Figure 8-13 MULTIFOCAL PHEOCHROMOCYTOMA ASSOCIATED WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) The adrenal gland contains a dominant pheochromocytoma as well as two smaller nodules (top) and an expanded pal... More about this image found in MULTIFOCAL PHEOCHROMOCYTOMA ASSOCIATED WITH MULTIPLE ENDOCRINE NEOPLASIA TY...
Images
in Familial and Syndrome-Related Pheochromocytoma and Paraganglioma
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) Figure 10-2 ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) A: The adrenal gland has diffuse medullary hyperplasia as well as multiple nodules that represent pheochromocytomas. B,C: The nodules of adr... More about this image found in ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) A:...
Images
in Physiology, Development, and Anatomy of the Adrenal Glands
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Figure 1-1 MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gonadal pathways are shown. Functions distinguishing the adrenal cortical zones from each other and from the gonads are determined by differential expression of steroi... More about this image found in MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gon...
Images
Published: 01 December 2024
ATYPICAL CELLS IN ADRENAL CORTICAL ADENOMA Figure 5-24 ATYPICAL CELLS IN ADRENAL CORTICAL ADENOMA This cortical adenoma exhibits focal “endocrine atypia” and lipomatous change. More about this image found in ATYPICAL CELLS IN ADRENAL CORTICAL ADENOMA This cortical adenoma exhibits ...
Images
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-7 ADRENAL CORTICAL CARCINOMA A large adrenal cortical carcinoma (ACC) from a 57-year-old woman simulated a renal cell carcinoma. The patient had no recognizable endocrine syndrome. Over half of the neoplasm was necrotic. More about this image found in ADRENAL CORTICAL CARCINOMA A large adrenal cortical carcinoma (ACC) from a...
Images
in Physiology, Development, and Anatomy of the Adrenal Glands
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
BODY AND HEAD OF A NODULAR ADRENAL GLAND Figure 1-24 BODY AND HEAD OF A NODULAR ADRENAL GLAND In this architecturally distorted gland in transverse section, the adrenal cortex is bright yellow, with focal nodularity. Medullary tissue is prominent and extends into both wings (alae) of the gland. T... More about this image found in BODY AND HEAD OF A NODULAR ADRENAL GLAND In this architecturally distorted...
Images
in Clinicopathologic Features of the Adrenal Cortex
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CUSHING SYNDROME Figure 3-1 CUSHING SYNDROME The clinical features of this disorder (left) can be caused by pituitary adrenocorticotropic hormone (ACTH) excess (top right), ectopic ACTH causing massive adrenal hyperplasia (right middle), or primary adrenal disease (bottom right). (From Netter FH.... More about this image found in CUSHING SYNDROME The clinical features of this disorder (left) can be caus...
Images
Published: 01 December 2024
PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE Figure 4-24 PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE A large pigmented macronodule and a larger pale yellow nodule with small areas of necrosis are seen. The patient was part of a family pedigree with the complex of myxomas, spotty pigmenta... More about this image found in PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE A large pigmented macrono...
Book
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Familial primary hyperaldosteronism (types I to IV and other variants) CYP11B1-CYP11B2; CLCN2; KCNJ5; CACN1AH; CACN1AD a Bilateral micro- and macronodular disease and adenoma <1% Seizure and neurologic abnormalities a Multiple endocrine neoplasia type 1 (MEN1...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Locations Cluster Other Associated Lesions RET 10q11.2 MEN2 (multiple endocrine neoplasia type 2) Adrenal 2 Medullary thyroid carcinoma; parathyroid hyperplasia or neoplasia Mucocutaneous ganglioneuromas (MEN2B) NF1 17q11.2 NF1 (neurofibromatosis type 1) Adrenal (rarely...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Because the adrenal cortex is the site of synthesis of several hormones, adrenal cortical tumors can be associated with endocrine syndromes that vary depending on the function of the hormone(s) released. The main hormones produced by the adrenal cortex are glucocorticoids, mineralocorticoids...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... recent World Health Organization (WHO) classification of endocrine and neuroendocrine tumors ( 1 ). Adrenal cortical nodular diseases are classified according to defined macroscopic and microscopic criteria, and the presence or absence of a particular endocrine syndrome ( 2 ). They may...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pheochromocytoma and paraganglioma has increased since the publica tion of the 2017 WHO classification of tumors of endocrine organs ( 8 ). However, reconsideration of the entire paraganglioma nomenclature may be beneficial in view of current understanding of both the commonalities and differences between...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Various neoplastic and non-neoplastic lesions cause enlargement of the adrenal glands. Aside from cortical and chromaffin cell tumors, the neoplasms most often encountered are primary benign or malignant tumors arising from non-endocrine cell types that reside in the normal adrenal gland...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... as functioning tumors. The risk of malignancy associated with an adrenal cortical adenoma is approximately 10 percent, with a significant association with size ( 3 ). Patients with incidentally discovered lesions that were thought to be nonfunctioning develop subtle or overt endocrine hyperfunction during follow...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-melanomatous) as well as testicular germ cell tumors, melanomas, lymphomas, and sarcomas. PRECURSOR LESIONS ACC is generally considered to arise de novo. However, data from patients with Carney complex ( 15 , 16 ) and multiple endocrine neoplasia 1 (MEN1)-associated ACC suggest that there may be progression...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in response to hypoxia. The organ of Zuckerkandl responds directly as an endocrine organ by secreting catecholamines that may protect against fetal heart failure ( 20 ). In contrast, the carotid body acts indirectly by transmitting sensory information to neurons in the central nervous system, which regulate...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...The adrenal glands are composite endocrine organs consisting of the mesodermal-derived cortex and neural crest-derived medulla. These components interact with each other, with peripheral endocrine and nonendocrine tissues, and with the central nervous system (CNS) in order to develop normally...
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