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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... factor, INSM1, analyzed immunohistochemically in neuroblastic tumors in comparison to other embryonal neoplasms, was expressed in 78 percent of a small series of NBLs, GNBLs, and GNs, in at least 20 percent of nuclei, but focal or patchy staining was also reported in a proportion of Ewing sarcomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the definitions, applying heterotopic to locations that cannot be explained by usual embryonic development and accessory to those that can. Ectopic adrenal tissue has several implications with regard to tumor diagnosis. Benign adrenal cortical tissue can mimic a variety of clear cell neoplasms, creating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... PHEOCHROMOCYTOMA Composite pheochromocytomas are rare tumors composed of pheochromocytoma admixed with other elements including ganglioneuroma, ganglioneuroblastoma, neuroblastoma, or peripheral nerve sheath tumor ( 41 , 44 , 90 – 95 ). These neoplasms are all derived from related embryonic lineages...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the first 8 weeks postovulation into 23 stages on the basis of morphologic development. While the system is not directly dependent on embryonic age or size, it correlates roughly with age, crown rump length, and main external characteristics, and allows for standardized assessments of growth and development...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... . Otolaryngol Case Rep   2019 ; 10 : 8 - 9 . 20. Tian   H , Hammer   RE , Matsumoto   AM , Russell   DW , McKnight   SL . The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development . Genes...
Images
Figure 52-1
Published: 15 November 2023
METASTASIS BY DIRECT EXTENSION Figure 52-1 METASTASIS BY DIRECT EXTENSION Left: This mediastinal embryonal carcinoma (black asterisk) metastasized to involve the heart by directly invading the anterior right and left ventricles (RV and LV, respectively). Right: This squamous cell carcinoma More about this image found in METASTASIS BY DIRECT EXTENSION Left: This mediastinal embryonal carcinoma ...
Images
Figure 39-2
Published: 15 November 2023
EBSTEIN ANOMALY: EMBRYOLOGY AND DELAMINATION DEFECT Figure 39-2 EBSTEIN ANOMALY: EMBRYOLOGY AND DELAMINATION DEFECT Left: Normal embryonic development of the septal and posterior tricuspid leaflets entails separation of leaflet and cordal tissue from the underlying endomyocardium. Right More about this image found in EBSTEIN ANOMALY: EMBRYOLOGY AND DELAMINATION DEFECT Left: Normal embryonic...
Images
Figure 1-40
Published: 15 November 2023
SYSTEMIC ARTERIES Figure 1-40 SYSTEMIC ARTERIES Left: Anterior view: aorta and its major branches. Right: Anterior view: embryonic derivation of the aorta and the proximal portion of the right and left coronary arteries. More about this image found in SYSTEMIC ARTERIES Left: Anterior view: aorta and its major branches. Righ...
Images
Images
Figure 1-3
Published: 15 November 2023
PERICARDIAL SINUSES AND RECESSES Figure 1-3 PERICARDIAL SINUSES AND RECESSES Left: Left lateral view. The transverse sinus (*) travels behind the great arteries. The ligament of Marshall (leftward white arrow) and the vein of Marshall (rightward white arrow) represent the embryonic remnants More about this image found in PERICARDIAL SINUSES AND RECESSES Left: Left lateral view. The transverse s...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... DIFFERENTIAL DIAGNOSIS McAllister and Fenoglio ( 25 ) reported four malignant pericardial germ cell tumors; the malignant foci were histologically composed of either embryonal carcinoma, squamous cell carcinoma arising in a teratoma, or choriocarcinoma. Three of these tumors metastasized to the lung, and one...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch01
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... SYSTEMIC ARTERIES Left: Anterior view: aorta and its major branches. Right: Anterior view: embryonic derivation of the aorta and the proximal portion of the right and left coronary arteries. SYSTEMIC VEINS Figure 1-41 SYSTEMIC VEINS Left: Anterior view of caval veins and their major tributaries...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch03
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., although the sinus node is primarily subepicardial and the AV node is subendocardial. The two nodes have similar microscopic features, conduction velocities, action potentials, and embryonic derivation. The AV (His) bundle and bundle branches, in contrast, are located along the interventricular septum...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch35
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... Calkoen   EE , Hazekamp   MG , Blom   NA , et al . Atrioventricular septal defect: from embryonic development to long-term follow-up . Int J Cardiol   2016 ; 202 : 784 - 95 . 11. Patolla   SH , Dearani   JA , Connolly   HM , et al . Repair of partial atrioventricular septal...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...METASTASIS BY DIRECT EXTENSION Figure 52-1 METASTASIS BY DIRECT EXTENSION Left: This mediastinal embryonal carcinoma (black asterisk) metastasized to involve the heart by directly invading the anterior right and left ventricles (RV and LV, respectively). Right: This squamous cell carcinoma...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch46
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... proposed that LHAS represents a hamartomatous process while others have suggested that it represents ectopia resulting from misplaced embryonic mesenchyme during atrial septation ( 27 ). This is a particularly attractive theory that may also explain some associations with adiposity as these fat cells...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch39
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., in a neonate with severe tricuspid regurgitation. Right: Prominent cardiomegaly is present, in an adult. (Courtesy of Dr. F. Cetta, Rochester, MN) EBSTEIN ANOMALY: EMBRYOLOGY AND DELAMINATION DEFECT Figure 39-2 EBSTEIN ANOMALY: EMBRYOLOGY AND DELAMINATION DEFECT Left: Normal embryonic development...
Images
Figure 13-12
Published: 01 August 2023
EMBRYONAL CARCINOMA Figure 13-12 EMBRYONAL CARCINOMA A: Medium power image of pure embryonal carcinoma showing relatively dyscohesive high grade tumor cells. B: Higher power image of embryonal carcinoma growing in a glandular pattern. C: A mixed malignant germ cell tumor containing embryonal More about this image found in EMBRYONAL CARCINOMA A: Medium power image of pure embryonal carcinoma show...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch41
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... ). In addition, cells of the embryonic endocardial cushion ultrastructurally resemble myxoma cells and may represent myxoma precursors ( 19 ). Taken together, these data strongly suggest that these resident, multipotential stem cells are likely the source of cardiac myxomas. The theory that cardiac myxomas...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch51
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... into varices may be the embryonic incorporation of remnants of the left venous valve into the right side of the atrial septum ( 19 ). This explanation, however, does not account for the rare cardiac varices that occur in the ventricles. Definition.  Cardiac varices are endocardial, unilocular, blood...