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Images
Published: 01 February 2024
ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE Figure 14-8 ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma in situ displays a mixed lentiginous, nested, and pagetoid pattern. It extends along the epithelial stromal junction of eccrine ducts (white arrows). B,C:... More about this image found in ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma i...
Images
Published: 01 February 2024
ACRAL LENTIGINOUS MELANOMA IN SITU Figure 14-5 ACRAL LENTIGINOUS MELANOMA IN SITU There is an irregular proliferation of predominantly solitary units of melanocytes of variable density along the dermoepidermal junction (arrows), with extension into eccrine ducts (arrowhead). More about this image found in ACRAL LENTIGINOUS MELANOMA IN SITU There is an irregular proliferation of ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-14
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Melanoma in situ: most tumors display a lentiginous pattern with a predominance of solitary units of melanocytes at the dermoepidermal junction (acral lentiginous melanoma); some show nested and/or pagetoid scatter Extension into eccrine ducts is common (syringotropism) Differential Diagnosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... can be provided ( fig. 23-2 ). Tumor thickness and tumor stage may need to be modified upon review of the subsequent excision. For adnexotropic melanoma, caution is necessary not to confuse melanoma in situ colonizing hair follicles or eccrine ducts with stromal invasion. For tumor cells invading...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the spinous cell layer ( 13 ). Such pagetoid growth should be limited to the epidermis directly above the scar. Typically, both nests and solitary units of melanocytes are seen above the basal cell layer ( fig. 6-4 ). In persistent nevi, melanocytes may also involve eccrine and follicular epithelia ( fig. 6-5...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-02
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... growth; 4) adnexotropism with intra-adnexal location such as within the follicular sheath, sebaceous gland, eccrine epithelium, or arrector pili muscle ( fig. 2-6 ); 5) splaying (single-filing, Indian filing) of rows of melanocytes between undisturbed collagen bundles ( figs. 2-4 , 2-7 ); and 6...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-13
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... resembling a skin adnexal eccrine tumor ( 14 ). Clinical Features. These rare lesions present as a palpable or image-detected mass or calcifications in the subareolar region. Occasionally, itchiness, tenderness, or discharge occur. Fungating lesions of the nipple have been reported in longstanding...
Images
in Embryology and Anatomy of the Lower Female Genital Tract
> Tumors of the Cervix, Vagina, and Vulva
Published: 01 February 2023
ADNEXAL STRUCTURES OF VULVAR SKIN Figure 1-17 ADNEXAL STRUCTURES OF VULVAR SKIN Hair shaft adnexal and eccrine (left) as well as apocrine (right) glands are limited to the labia majora. More about this image found in ADNEXAL STRUCTURES OF VULVAR SKIN Hair shaft adnexal and eccrine (left) as...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-1
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... is lined by keratinizing squamous epithelium. Skin adnexal structures, including hair follicles and apocrine, eccrine, and sebaceous glands, are limited to the labia majora ( fig. 1-17 ). Hair follicles are prominent in the lateral portion, whereas the medial aspect shows a progressive loss of hair...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... related to rests of the embryonic “milk line.” More recent studies, however, have challenged this theory, including observations that mammary-like glands, which are related to eccrine glands, are a normal constituent of the anogenital region and are morphologically and immunophenotypically similar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-05
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... squamous epithelium, with underlying dermis-like tissue containing eccrine sweat glands and pilosebaceous units, in an organotypical arrangement similar to that of normal skin ( fig. 5-29 ). The presence of additional elements does not exclude a diagnosis of dermoid cyst and includes those tissues commonly...
Images
Published: 01 September 2021
ECCRINE DUCTAL CARCINOMA, NOS Figure 1-286 ECCRINE DUCTAL CARCINOMA, NOS Focal tumor necrosis. More about this image found in ECCRINE DUCTAL CARCINOMA, NOS Focal tumor necrosis.
Images
Published: 01 September 2021
SYRINGOID ECCRINE CARCINOMA Figure 1-205 SYRINGOID ECCRINE CARCINOMA Left: A diffusely infiltrative tumor invades subcutaneous adipose tissue. Right: The tumor is composed of well-formed ducts invading fat and skeletal muscle. More about this image found in SYRINGOID ECCRINE CARCINOMA Left: A diffusely infiltrative tumor invades s...
Images
Published: 01 September 2021
SYRINGOID ECCRINE CARCINOMA Figure 1-206 SYRINGOID ECCRINE CARCINOMA The ducts are lined by a single cell layer of cuboidal cells showing limited cytologic atypia. More about this image found in SYRINGOID ECCRINE CARCINOMA The ducts are lined by a single cell layer of ...
Images
Published: 01 September 2021
SQUAMOID ECCRINE DUCTAL CARCINOMA Figure 1-231 SQUAMOID ECCRINE DUCTAL CARCINOMA Diffusely infiltrative tumor in a desmoplastic stroma invades subcutaneous adipose tissue. More about this image found in SQUAMOID ECCRINE DUCTAL CARCINOMA Diffusely infiltrative tumor in a desmop...
Images
Published: 01 September 2021
SQUAMOID ECCRINE DUCTAL CARCINOMA Figure 1-232 SQUAMOID ECCRINE DUCTAL CARCINOMA Left: The superficial aspect of the tumor is indistinguishable from squamous cell carcinoma. There is a connection with the overlying epidermis. Above: Higher magnification highlights the malignant squamous differen... More about this image found in SQUAMOID ECCRINE DUCTAL CARCINOMA Left: The superficial aspect of the tumo...
Images
Published: 01 September 2021
SQUAMOID ECCRINE DUCTAL CARCINOMA Figure 1-233 SQUAMOID ECCRINE DUCTAL CARCINOMA In the deeper aspect the tumor is arranged in nests and strands of pleomorphic epithelioid cells with duct differentiation in a sclerotic stroma. More about this image found in SQUAMOID ECCRINE DUCTAL CARCINOMA In the deeper aspect the tumor is arrang...
Images
Published: 01 September 2021
SQUAMOID ECCRINE DUCTAL CARCINOMA Figure 1-234 SQUAMOID ECCRINE DUCTAL CARCINOMA Note the degree of nuclear pleomorphism and atypical mitotic activity. More about this image found in SQUAMOID ECCRINE DUCTAL CARCINOMA Note the degree of nuclear pleomorphism ...
Images
Published: 01 September 2021
SQUAMOID ECCRINE DUCTAL CARCINOMA Figure 1-235 SQUAMOID ECCRINE DUCTAL CARCINOMA Duct differentiation is demonstrated by carcinoembryonic antigen (CEA) staining. More about this image found in SQUAMOID ECCRINE DUCTAL CARCINOMA Duct differentiation is demonstrated by ...
Images
Published: 01 September 2021
ECCRINE DUCTAL CARCINOMA, NOS Figure 1-283 ECCRINE DUCTAL CARCINOMA, NOS The tumor is composed of nests and strands that diffusely infiltrate the dermis. More about this image found in ECCRINE DUCTAL CARCINOMA, NOS The tumor is composed of nests and strands t...
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