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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch19
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... multiple organ systems, resulting in unusual facial features (hypertelorism, ptosis, low-set ears, and webbed neck), short stature, developmental delay, and cardiac conditions (including cardiomyopathy and congenital heart disease). Nearly a quarter of individuals with NS manifest an underlying...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch38
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... Earing MG , Cetta F , Driscoll DJ , et al . Long-term results of the Fontan operation for double-inlet left ventricle . Am J Cardiol 2005 ; 96 : 291 - 8 . 24. Martinez RM , Anderson RH . Echo-morphological correlates in atrioventricular valvar atresia . Cardiol...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-06
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... serous tumors from malignant mesothelioma . Am J Surg Pathol 2010 ; 34 : 627 - 35 . 69. Gaffey MJ , Mills SE , Boyd JC . Aggressive papillary tumor of middle ear/temporal bone and adnexal papillary cystadenoma. Manifestations of von Hippel-Lindau disease . Am J Surg Pathol...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-2
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... of growth and development, ear and genital abnormalities, and deficiency of gonadotropin. Dubowitz syndrome has an autosomal recessive pattern of inheritance, but the underlying genetic abnormalities are unknown. In addition to hypoparathyroidism, individuals with Dubowitz syndrome have short stature...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-5
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... in neuroendocrine tumors, but pancreatic ductal adenocarcinomas were negative ( 129 ). Another recent study evaluated 97 neuroendocrine tumors of various types (middle ear adenoma, paragangliomas, PitNET, medullary thyroid carcinoma, olfactory neuroblastoma, small cell carcinoma, large cell neuroendocrine carcinoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-3
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... in 96 percent of patients in one study ( 362 ). The onset may be sudden or gradual, and may be preceded by an upper respiratory tract infection. The pain may be limited to the region of the thyroid gland or radiate to the upper neck, jaw, throat, upper chest, and ears. Fever, fatigue, malaise, anorexia...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
.... It is occasionally associated with midline congenital defects, including spinal dysraphism, indeterminate visceral situs, and the Cornelia de Lange syndrome (associated with mental and growth retardation, low-set ears, anteverted nostrils, and spade-like hands with short tapering fingers) ( 132 ). It can also occur...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... Invest 2020 ; 130 : 641 - 54 . 133. Nolen LD , Amor D , Haywood A , et al . Deletion at 14q22-23 indicates a contiguous gene syndrome comprising anophthalmia, pituitary hypoplasia, and ear anomalies . Am J Med Genet A 2006 ; 140 : 1711 - 8 . 134. Frisch H , Kim...
Images
Published: 01 September 2021
KAPOSI SARCOMA Figure 2-137 KAPOSI SARCOMA A: HHV-8-positive endothelial cells are present in this early stage Kaposi sarcoma. B–D: Spindled cells of this nodular Kaposi sarcoma are positive for CD34 (B), podoplanin (C), and HHV-8 (D). More about this image found in KAPOSI SARCOMA A: HHV-8-positive endothelial cells are present in this ear...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-6
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
..., in particular BSEP deficiency. Patients with FIC1 (familial intrahepatic cholestasis 1) deficiency have extrahepatic disease manifestations because the FIC1 protein is necessary for the normal function of other organs, including the pancreas and ear tubes. Thus, patients with FIC1 deficiency may have hearing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-10
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... characteristic dysmorphic features, such as a broad forehead with depressed nasal bridge, epicanthal folds, and low set ears. The childhood presentation of the disease is more variable, and may involve delayed developmental milestones. Sensorineural deafness is almost always present, and patients may have ocular...
Images
Published: 01 September 2021
CUTANEOUS SIGNET RING CELL ANGIOSARCOMA Figure 2-160 CUTANEOUS SIGNET RING CELL ANGIOSARCOMA A: An elderly patient developed an elevated lesion behind the left ear. Histology shows an infiltrating neoplasm composed of clear, signet ring cells reminiscent of signet ring cell carcinoma. B: Dilated... More about this image found in CUTANEOUS SIGNET RING CELL ANGIOSARCOMA A: An elderly patient developed an...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 7
Published: 01 September 2021
10.55418/9781933477121-3
ISBN-10: 1-933477-12-1
ISBN: 978-1-933477-12-1
... manner ( 252 ). It is a provisional entity in the 2016 WHO classification ( 247 , 248 ). Clinical Features . First described on the ear in 2007, the clinical spectrum has been subsequently expanded to include cases arising elsewhere on the face and other acral sites. This is a rare entity primarily...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 7
Published: 01 September 2021
10.55418/9781933477121-1
ISBN-10: 1-933477-12-1
ISBN: 978-1-933477-12-1
..., presenting as scaly, erythematous plaques measuring few millimeters to a centimeter on a background of chronically sun-damaged skin. The scalp, face, ear, lips, neck, forearms, and hands are particularly affected. Similar lesions are also seen after psoralen and ultraviolet A (PUVA) treatment (PUVA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 7
Published: 01 September 2021
10.55418/9781933477121-2
ISBN-10: 1-933477-12-1
ISBN: 978-1-933477-12-1
... round, vesicular nuclei with prominent nucleoli. CUTANEOUS SIGNET RING CELL ANGIOSARCOMA Figure 2-160 CUTANEOUS SIGNET RING CELL ANGIOSARCOMA A: An elderly patient developed an elevated lesion behind the left ear. Histology shows an infiltrating neoplasm composed of clear, signet ring cells...
Images
Published: 01 May 2021
MYOEPITHELIAL CARCINOMA Figure 6-329 MYOEPITHELIAL CARCINOMA Gross examination of this parotid gland tumor shows an irregular multinodular lesion infiltrating into the overlying skin and ear. Foci of hemorrhage are noted. More about this image found in MYOEPITHELIAL CARCINOMA Gross examination of this parotid gland tumor show...
Images
Published: 01 May 2021
GLANDULAR LYMPH NODES Figure 1-7 GLANDULAR LYMPH NODES The parotid gland has several periparotid and intraparotid lymph nodes that drain portions of the ear, temporal region, lateral face, eyelids, and conjunctiva, and they in turn drain into the internal jugular lymph nodes. Submandibular gland ... More about this image found in GLANDULAR LYMPH NODES The parotid gland has several periparotid and intrap...
Images
Published: 01 May 2021
ANATOMIC RELATIONSHIP OF PAROTID AND SUBMANDIBULAR GLANDS Figure 1-5 ANATOMIC RELATIONSHIP OF PAROTID AND SUBMANDIBULAR GLANDS The anatomic position and relationship of the parotid and submandibular glands to the ear, zygomatic arch, mandible, and masseter muscle in a lateral view of the head are... More about this image found in ANATOMIC RELATIONSHIP OF PAROTID AND SUBMANDIBULAR GLANDS The anatomic pos...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 5
Published: 01 May 2021
10.55418/9781933477947-09
ISBN-10: 1-933477-94-6
ISBN: 978-1-933477-94-7
... in Merkel cell carcinoma of the head and neck: a series of 14 cases . Ear Nose Throat J 2016 ; 95 : 398 - 404 . 39. Knopf A , Bas M , Hofauer B , Mansour N , Stark T . Clinicopathological characteristics of head and neck Merkel cell carcinomas . Head Neck 2017 ; 39...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 5
Published: 01 May 2021
10.55418/9781933477947-01
ISBN-10: 1-933477-94-6
ISBN: 978-1-933477-94-7
... of the sternocleidomastoid muscle ( fig. 1-5 ). The anterior portion of the parotid gland lying against the mandibular ramus slightly covers the posterior edge of the masseter muscle. Posteriorly, the gland is bounded by the ear, the mastoid process, and the anterior edge of the sternocleidomastoid muscle. The deep portion...
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