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dysplastic

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-04
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...The melanocytic nevus commonly referred to as dysplastic is a fairly common acquired lesion with clinical and pathologic features intermediate between an ordinary nevus and superficial spreading melanoma. Other terms for this nevus include melanocytic nevus with architectural disorder...
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<span class="search-highlight">DYSPLASTIC</span> NEVUS  A: Multiple red and brown lesions are present on the uppe...
Published: 01 February 2024
DYSPLASTIC NEVUS Figure 4-1 DYSPLASTIC NEVUS A: Multiple red and brown lesions are present on the upper back shoulder. The arrow points to a lesion, which was excised, and the diagnosis histopathologically confirmed as dysplastic nevus. B: The lesion has a diameter of more than 4 mm and displays... More about this image found in DYSPLASTIC NEVUS A: Multiple red and brown lesions are present on the uppe...
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<span class="search-highlight">DYSPLASTIC</span> NEVUS  A: Multiple pigmented lesions are present on the back. Th...
Published: 01 February 2024
DYSPLASTIC NEVUS Figure 4-2 DYSPLASTIC NEVUS A: Multiple pigmented lesions are present on the back. The lesion, which was biopsied and histologically confirmed, is highlighted. B: The lesion displays some asymmetry, has an irregular peripheral border, and has some variation in pigmentation, with... More about this image found in DYSPLASTIC NEVUS A: Multiple pigmented lesions are present on the back. Th...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS  A: Nests vary in size and shape. There is a band...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS Figure 4-3 COMPOUND DYSPLASTIC NEVUS A: Nests vary in size and shape. There is a band-like lymphocytic infiltrate. B: The melanocytic proliferation is predominantly junctional, but a few nests of melanocytes are seen in a fibrotic dermis. More about this image found in COMPOUND DYSPLASTIC NEVUS A: Nests vary in size and shape. There is a band...
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PIGMENTED LENTIGINOUS COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS  A: The silhouette of a bro...
Published: 01 February 2024
PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS Figure 4-4 PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS A: The silhouette of a broad plaque-like lesion with epidermal hyperplasia. B: The epidermis shows lentigo-like hyperplasia. Melanin pigment is present in keratinocytes and melanocytes. Sol... More about this image found in PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS A: The silhouette of a bro...
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LENTIGINOUS COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS WITH LAMELLAR FIBROSIS  Thin layers o...
Published: 01 February 2024
LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Figure 4-5 LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Thin layers of fibrosis surround rete ridges, creating a zone separating junctional from dermal melanocytes. There is associated bland-like inflammation. More about this image found in LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Thin layers o...
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INFLAMED <span class="search-highlight">DYSPLASTIC</span> NEVUS  The compound nevus displays features of a dyspla...
Published: 01 February 2024
INFLAMED DYSPLASTIC NEVUS Figure 4-6 INFLAMED DYSPLASTIC NEVUS The compound nevus displays features of a dysplastic nevus (e.g., fusion of junctional nests) and is associated with a dense band-like lymphocytic infiltrate involving the dermoepidermal junction and superficial dermis. More about this image found in INFLAMED DYSPLASTIC NEVUS The compound nevus displays features of a dyspla...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS WITH PARTIAL REGRESSION  There is a gap (arrows) ...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION Figure 4-7 COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION There is a gap (arrows) in the dermal melanocyte population, with inflammation and slightly hypervascular stroma separating dermal nevus cell aggregates. More about this image found in COMPOUND DYSPLASTIC NEVUS WITH PARTIAL REGRESSION There is a gap (arrows) ...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS  Melanocyte nests vary in size and shape, and the...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS Figure 4-8 COMPOUND DYSPLASTIC NEVUS Melanocyte nests vary in size and shape, and there is a lentiginous proliferation of solitary units of melanocytes. Some junctional melanocytes show slight nuclear enlargement and hyperchromatism. Mild lamellar fibrosis is present (ar... More about this image found in COMPOUND DYSPLASTIC NEVUS Melanocyte nests vary in size and shape, and the...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS  There is architectural disorder of melanocytes a...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS Figure 4-9 COMPOUND DYSPLASTIC NEVUS There is architectural disorder of melanocytes at the dermoepidermal junction, with fusion of rete ridges. Many junctional melanocyte nuclei are larger than (some up to twice the size of) keratinocyte nuclei. More about this image found in COMPOUND DYSPLASTIC NEVUS There is architectural disorder of melanocytes a...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS  Melanocytes are dispersed as solitary units and ...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS Figure 4-10 COMPOUND DYSPLASTIC NEVUS Melanocytes are dispersed as solitary units and small nests at the dermoepidermal junction. Most melanocyte nuclei are larger than basilar keratinocyte nuclei. Some of the melanocytes display irregular nuclear contours and/or hyperch... More about this image found in COMPOUND DYSPLASTIC NEVUS Melanocytes are dispersed as solitary units and ...
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COMPOUND <span class="search-highlight">DYSPLASTIC</span> NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES  A: Compound...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES Figure 4-11 COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES A: Compound dysplastic nevus (hematoxylin and eosin [H&E]-stain). B: Immunostain for PRAME. Most nuclei of junctional melanocytes (long arrow) and intrade... More about this image found in COMPOUND DYSPLASTIC NEVUS WITH RARE PRAME-POSITIVE MELANOCYTES A: Compound...
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COMBINED BAP1-INACTIVATED COMPOUND NEVUS WITH FEATURES OF A <span class="search-highlight">DYSPLASTIC</span> NEVU...
Published: 01 February 2024
COMBINED BAP1-INACTIVATED COMPOUND NEVUS WITH FEATURES OF A DYSPLASTIC NEVUS Figure 10-9 COMBINED BAP1-INACTIVATED COMPOUND NEVUS WITH FEATURES OF A DYSPLASTIC NEVUS A: The compound melanocytic proliferation is predominantly composed of small epithelioid melanocytes (arrows). Junctional nests var... More about this image found in COMBINED BAP1-INACTIVATED COMPOUND NEVUS WITH FEATURES OF A DYSPLASTIC NEVU...
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SCALP NEVUS  A: The compound nevus displays plaque-like growth and has a ju...
Published: 01 February 2024
SCALP NEVUS Figure 5-9 SCALP NEVUS A: The compound nevus displays plaque-like growth and has a junctional shoulder. B: It contains areas displaying features of a dysplastic nevus with fusion of nests, random atypia, and stromal fibrosis. More about this image found in SCALP NEVUS A: The compound nevus displays plaque-like growth and has a ju...
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ACQUIRED MELANOCYTIC NEVI WITH MINOR ARCHITECTURAL DISORDER  A: The lesion ...
Published: 01 February 2024
ACQUIRED MELANOCYTIC NEVI WITH MINOR ARCHITECTURAL DISORDER Figure 3-23 ACQUIRED MELANOCYTIC NEVI WITH MINOR ARCHITECTURAL DISORDER A: The lesion is small and circumscribed. It displays minor asymmetry. B: This compound nevus has a shoulder, but lacks other features of a dysplastic nevus. More about this image found in ACQUIRED MELANOCYTIC NEVI WITH MINOR ARCHITECTURAL DISORDER A: The lesion ...
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NEVUS CHANGING UNDER BRAF INHIBITOR THERAPY  A: The nevus shows features of...
Published: 01 February 2024
NEVUS CHANGING UNDER BRAF INHIBITOR THERAPY Figure 6-9 NEVUS CHANGING UNDER BRAF INHIBITOR THERAPY A: The nevus shows features of an inflamed dysplastic nevus. B: Junctional nests at the tips of rete ridges vary in size and shape. A few suprabasilar melanocytes are seen in the center of the lesi... More about this image found in NEVUS CHANGING UNDER BRAF INHIBITOR THERAPY A: The nevus shows features of...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... features, and dysplastic, blue, Spitz, or other nevi may also involve these sites. Also, atypical features said to be related to a “special site” are not site specific: they can be seen in melanocytic nevi anywhere. ACRAL NEVI Clinical Features.  Acral melanocytic nevi are common, especially...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... features of dysplastic nevi with architectural disorder and atypia at the dermoepidermal junction ( fig. 10-9 ) as well as inflammation and at times lamellar fibrosis. Table 10-2 BAP1-TUMOR PREDISPOSITION SYNDROME (TPDS) Criteria for suspecting the syndrome:  Two or more BAP1-TPDS tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...  Dysplastic nevus  Traumatized nevus  Congenital nevus  Pagetoid carcinomas (extramammary Paget disease, pagetoid squamous cell carcinoma in situ, sebaceous carcinoma in situ) Molecular Genetic Findings  Cytogenetic aberrations detectable by FISH or CGH/SNP array are common  Most common...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... history (recorded clinical onset of a melanocytic lesion) is the best parameter for the distinction of small “true” congenital nevi from acquired nevi displaying “congenital” features. Common Ordinary Melanocytic Nevus versus Dysplastic Nevus. Biopsied lesions of acquired nevi commonly show some minor...