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NORMAL SEROSAL MEMBRANES  A,B: The pleura is covered by a single layer of f...
Published: 01 June 2022
NORMAL SEROSAL MEMBRANES Figure 1-1 NORMAL SEROSAL MEMBRANES A,B: The pleura is covered by a single layer of flattened or cuboidal mesothelial cells. C: The surface is often partly or completely denuded due to specimen handling or secondary to pathology. D: Normal visceral pleura has a thin lay... More
Images
NORMAL SEROSAL MEMBRANES  A,B: The pleura is covered by a single layer of f...
Published: 01 June 2022
NORMAL SEROSAL MEMBRANES Figure 1-1 NORMAL SEROSAL MEMBRANES A,B: The pleura is covered by a single layer of flattened or cuboidal mesothelial cells. C: The surface is often partly or completely denuded due to specimen handling or secondary to pathology. D: Normal visceral pleura has a thin lay... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-8
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... ( 94 ). Disseminated peritoneal leiomyomatosis (DPL) is a condition associated with typical uterine leiomyomas ( 102 ). There is also a strong association with pregnancy and oral contraceptive use. Rarely, DPL occurs in association with endometriosis ( 103 ). The disorder is viewed by some...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-1
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... layer of fibrosis deep to the mesothelial cells, with two elastin layers often visible and separated by a further layer of fibrosis (elastin van Gieson [EVG] stain). E: The elastin layers can become less defined, with more disordered elastosis, in chronic disease, interspersed by a thin layer...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-6
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... disease: a neoplastic disorder . Hum Pathol   1999 ; 30 : 1093 - 6 . 80. Yahng   SA , Kang   HH , Kim   SK , et al . Erdheim-Chester disease with lung involvement mimicking pulmonary lymphangitic carcinomatosis . Am J Med Sci   2009 ; 337 : 302 - 4 . 81. Protopapadakis   C...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-7
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... those of vascular origin, have been reported to mimic mesothelioma as well ( 8 – 10 ), as has the systemic histiocytic disorder Erdheim-Chester disease (see chapter 6 ) ( 11 ). Effusion. Clinically, rates of malignant pleural effusion increase with age, starting at 30 to 40 years, but reaching a peak...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-4
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
...)(q23;p13) ( 55 ). There appears to be no loss of BAP1 staining ( 55 ). Many authors view multicystic mesothelioma as a reactive disorder ( 56 ), although others describe morphologic overlap with WDPMT and adenomatoid tumors ( 9 , 12 ), so it is possible that the pathogenesis of multicystic mesothelioma...
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UREA CYCLE <span class="search-highlight">DISORDER</span>  Macrovesicular steatosis, a non-specific finding, in a...
Published: 01 January 2022
UREA CYCLE DISORDER Figure 10-28 UREA CYCLE DISORDER Macrovesicular steatosis, a non-specific finding, in argino-succinic aciduria. More
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UREA CYCLE <span class="search-highlight">DISORDER</span>  Left: Glycogen accumulation in hepatocytes may mimic g...
Published: 01 January 2022
UREA CYCLE DISORDER Figure 10-29 UREA CYCLE DISORDER Left: Glycogen accumulation in hepatocytes may mimic glycogen storage disease. Right: Bridging fibrosis is seen in this example (trichrome). More
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POLYMORPHIC POST-TRANSPLANT LYMPHOPROLIFERATIVE <span class="search-highlight">DISORDER</span>  The portal tract ...
Published: 01 January 2022
POLYMORPHIC POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER Figure 11-21 POLYMORPHIC POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER The portal tract is expanded by a mixed inflammatory infiltrate consisting of lymphocytes of varying sizes and scattered plasma cells. More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-12
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
...Table 12-2 MAJOR CAUSES OF BUDD-CHIARI SYNDROME Common Causes Uncommon Causes Inherited thrombophilic disorders Inflammatory conditions  Factor V Leiden mutation  Behcet disease  Prothrombin mutation  Hypereosinophilic syndrome  Antithrombin III deficiency  Granulomatous...
Images
HEREDITARY FRUCTOSE INTOLERANCE  Left: Portal fibrosis with minimal steatos...
Published: 01 January 2022
HEREDITARY FRUCTOSE INTOLERANCE Figure 10-21 HEREDITARY FRUCTOSE INTOLERANCE Left: Portal fibrosis with minimal steatosis in a case of hereditary fructose intolerance. Histologic features are not specific for the disorder. Right: Portal and pericellular fibrosis in hereditary fructose intoleranc... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-10
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
...Table 10-1 NONGENETIC DISORDERS WITH IRON OVERLOAD Chronic transfusion (sickle cell disease, thalassemia major, etc.) Alcoholic liver disease Porphyria cutanea tarda Hemodialysis Chronic viral hepatitis (hepatitis B and hepatitis C) Nonalcoholic fatty liver disease Table 10-2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-13
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... chain due to genetic defect in IL2RG; others include adenosine deaminase deficiency, purine nucleoside deficiency, and T-cell receptor deficiencies Graft versus host disease, sinusoidal obstruction syndrome after hematopoietic stem cell transplant, post-transplant lymphoproliferative disorders...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-6
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... embryologic disorder with failure to develop normal right-left axis organization of organs, including severe cardiac disease  Mitochondrial depletion syndrome  Niemann-Pick type C Large-Scale Chromosomal Abnormalities  Trisomy 11  Trisomy 18  Monosomy X a CMV = cytomegalovirus...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-14
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... Histology typically shows glycogenosis, steatosis, or a mixture of both Alpha-1-antitrypsin deficiency Globules may not be evident on histology until about age 6 months Bile salt deficiency disorders Often a strong family history; nonspecific biliary pattern of cirrhosis Wilson disease...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-9
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... vein thrombosis; portal vein thrombosis can also lead to de novo steatosis Genetic disease Ataxia telangiectasia ( 84 ) Bardet-Biedl syndrome Truncal obesity can develop in infancy; diabetes mellitus is also common Citrullinemia ( 85 ) Congenital disorders of glycosylation The fat...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-1
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... in the intensive care unit Drug-induced liver injury Intrahepatic cholestasis of pregnancy Paraneoplastic syndromes  Lymphomas are most common  Others include renal cell carcinoma (Stauffer syndrome) PFIC disordersATP8B1 mutations (PFIC1); mutated protein is called FIC1...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-11
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... slightly larger than normal. POLYMORPHIC POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER Figure 11-21 POLYMORPHIC POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER The portal tract is expanded by a mixed inflammatory infiltrate consisting of lymphocytes of varying sizes and scattered plasma cells. CENTRAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-8
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... of 899 patients with drug-induced liver injury: the DILIN prospective study . Gastroenterology   2015 ; 148 : 1340 – 52 . 41. Bénichou   C . Criteria of drug-induced liver disorders. Report of an international consensus meeting . J Hepatol   1990 ; 11 : 272 – 6 . 42. Aithal   PG...