MULTIPLE SEROUS CYSTADENOMAS IN VON HIPPEL-LINDAU (VHL) DISEASE Figure 4-5 MULTIPLE SEROUS CYSTADENOMAS IN VON HIPPEL-LINDAU (VHL) DISEASE The entire pancreas is filled with multiple discrete microcys tic neoplasms that largely replace the normal parenchyma. In some of the neoplasms the stellate ... More about this image found in MULTIPLE SEROUS CYSTADENOMAS IN VON HIPPEL-LINDAU (VHL) DISEASE The entire...

MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Figure 4-11 MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Left: Solid, nodular, yellow-white neuroendocrine tumor is adjacent to microcystic serous cystadenoma. Right: At higher power, the neuroendocrine and sero... More about this image found in MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Left: Sol...

DISEASE-SPECIFIC SURVIVAL OF PATIENTS WITH MUCINOUS CYSTIC NEOPLASM Figure 5-33 DISEASE-SPECIFIC SURVIVAL OF PATIENTS WITH MUCINOUS CYSTIC NEOPLASM The presence (x) or absence (o) of an associated invasive carcinoma is the best predictor of survival following surgical resection of a mucinous cyst... More about this image found in DISEASE-SPECIFIC SURVIVAL OF PATIENTS WITH MUCINOUS CYSTIC NEOPLASM The pr...

ACINAR CELL CARCINOMA Figure 9-32 ACINAR CELL CARCINOMA Metastatic disease in the liver (left) and invasion of the duodenum (right). More about this image found in ACINAR CELL CARCINOMA Metastatic disease in the liver (left) and invasion ...

PATIENT SURVIVAL IN ACINAR CELL CARCINOMA Figure 9-34 PATIENT SURVIVAL IN ACINAR CELL CARCINOMA The median survival time for patients with localized (red line) disease is 56.9 months and for patients with advanced (blue line) disease is 19.6 months ( 39 ). More about this image found in PATIENT SURVIVAL IN ACINAR CELL CARCINOMA The median survival time for pat...

SOLID PSEUDOPAPILLARY NEOPLASM Figure 11-31 SOLID PSEUDOPAPILLARY NEOPLASM Lymph node metastases (left) are rare. Typically, the liver is the main site of metastatic disease (right). More about this image found in SOLID PSEUDOPAPILLARY NEOPLASM Lymph node metastases (left) are rare. Typi...

EXTRAMAMMARY PAGET DISEASE Figure 5-44 EXTRAMAMMARY PAGET DISEASE This excision specimen shows the extensive mucosal changes characteristic of Paget disease, including thickened, irregular white patches as well as a red velvety mucosa. It is difficult to delineate the leading edge of the neoplast... More about this image found in EXTRAMAMMARY PAGET DISEASE This excision specimen shows the extensive muco...

EXTRAMAMMARY PAGET DISEASE Figure 5-45 EXTRAMAMMARY PAGET DISEASE A: Atypical epithelioid cells with moderate to abundant amounts of pale eosinophilic cytoplasm and round nuclei with variably prominent nucleoli infiltrate the epidermis along the basal layer. Compressed basal keratinocytes are pre... More about this image found in EXTRAMAMMARY PAGET DISEASE A: Atypical epithelioid cells with moderate to ...

INVASIVE PAGET DISEASE Figure 5-46 INVASIVE PAGET DISEASE Left: Superficial invasion of the dermis by Paget cells can be subtle and features a single cell pattern of infiltration. Right: Some tumors show a more established invasive process, as in this example with prominent gland formation. More about this image found in INVASIVE PAGET DISEASE Left: Superficial invasion of the dermis by Paget c...

EXTRAMAMMARY PAGET DISEASE, INTESTINAL TYPE Figure 5-47 EXTRAMAMMARY PAGET DISEASE, INTESTINAL TYPE The presence of goblet or signet ring cell differentiation should raise the possibility of secondary Paget disease of colorectal origin; however, some examples of primary vulvar Paget disease show ... More about this image found in EXTRAMAMMARY PAGET DISEASE, INTESTINAL TYPE The presence of goblet or sign...

SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN Figure 5-48 SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN The presence of acantholysis and clefting between malignant cells and squamous epithelium is more often seen with spread of a urothelial primary (left). Nonetheless, the lesion may bear close res... More about this image found in SECONDARY PAGET DISEASE OF UROTHELIAL ORIGIN The presence of acantholysis ...

CROHN DISEASE Figure 5-99 CROHN DISEASE A non-necrotizing granuloma with central multinucleated giant cells is present in the superficial dermis. More about this image found in CROHN DISEASE A non-necrotizing granuloma with central multinucleated gian...