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ADENOMATOID TUMOR  The characteristic “thread-like bridging strands” of cyt...
Published: 01 August 2022
ADENOMATOID TUMOR Figure 8-24 ADENOMATOID TUMOR The characteristic “thread-like bridging strands” of cytoplasm that stretch across the lumens of tubules are common and a supportive diagnostic feature. More
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CHORIOCARCINOMA  Left: A large zone of hemorrhage is bordered by a rim of c...
Published: 01 August 2022
CHORIOCARCINOMA Figure 4-139 CHORIOCARCINOMA Left: A large zone of hemorrhage is bordered by a rim of choriocarcinoma. Right: A broad band of choriocarcinoma with the diagnostic admixture of syncytiotrophoblasts and mononucleated trophoblastic cells surrounds a central area of hemorrhage and fib... More
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EPIDERMOID CYST:ULTRASONOGRAM  The concentric hyperechoic signals cause a t...
Published: 01 August 2022
EPIDERMOID CYST:ULTRASONOGRAM Figure 5-31 EPIDERMOID CYST:ULTRASONOGRAM The concentric hyperechoic signals cause a targetoid appearance. (Fig. 22-12D from Sommers D, Winter T. The scrotum. In: Rumack CM, Levine D. Diagnostic ultrasound, 5th ed. Philadelphia: Elsevier; 2018:830.) More
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CARCINOSARCOMA OF PARATESTICULAR REGION  This tumor was favored to arise fr...
Published: 01 August 2022
CARCINOSARCOMA OF PARATESTICULAR REGION Figure 8-17 CARCINOSARCOMA OF PARATESTICULAR REGION This tumor was favored to arise from the rete testis but a müllerian-type tumor remained a diagnostic possibility. Left: Glands lined by malignant epithelium are set in a cellular, neoplastic stroma. Rig... More
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POSTCHEMOTHERAPY GLANDULAR YOLK SAC TUMOR  A: The glands have prominent sub...
Published: 01 August 2022
POSTCHEMOTHERAPY GLANDULAR YOLK SAC TUMOR Figure 4-238 POSTCHEMOTHERAPY GLANDULAR YOLK SAC TUMOR A: The glands have prominent subnuclear vacuoles, thereby resembling early secretory endometrium. B: Prominent bands of extracellular basement membrane are a useful diagnostic clue in this case. C: ... More
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ADENOMATOID TUMOR  A: The solid growth of cells with plump eosinophilic cyt...
Published: 01 August 2022
ADENOMATOID TUMOR Figure 8-23 ADENOMATOID TUMOR A: The solid growth of cells with plump eosinophilic cytoplasm is a morphology that may lead to diagnostic confusion. B: Predominantly solid growth, less conspicuous vacuoles, and brightly eosinophilic cytoplasm may make the recognition of adenomat... More
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SPERMATOCYTIC TUMOR  A multinodular tumor with encephaloid, gelatinous, and...
Published: 01 August 2022
SPERMATOCYTIC TUMOR Figure 5-61 SPERMATOCYTIC TUMOR A multinodular tumor with encephaloid, gelatinous, and hemorrhagic areas. (Fig. 47.25 from Ulbright TM, Berney DM. Testicular and paratesticular tumors. In: Mills SE, Greenson JK, Hornick JL, Longacre TA, Reuter VE, eds. Sternberg’s diagnostic s... More
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NORMAL CELLS: CYTOLOGIC PREPARATION  Sertoli cells with prominent nucleoli,...
Published: 01 August 2022
NORMAL CELLS: CYTOLOGIC PREPARATION Figure 2-51 NORMAL CELLS: CYTOLOGIC PREPARATION Sertoli cells with prominent nucleoli, primary spermatocytes with coarse strands of chromatin, and spermatids (arrows) with small dense nuclei are seen. (Fig. 33-18B from Koss LG, Melamed MR. The prostate and the ... More
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SPLENIC-TESTICULAR FUSION, CONTINUOUS TYPE  Splenic tissue forms an intrapa...
Published: 01 August 2022
SPLENIC-TESTICULAR FUSION, CONTINUOUS TYPE Figure 11-105 SPLENIC-TESTICULAR FUSION, CONTINUOUS TYPE Splenic tissue forms an intraparenchymal mass in the upper pole of the testis. It was connected by a cord (truncated in this image) of splenic tissue to the normally located spleen. (Fig. 47.123 fr... More
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YOLK SAC TUMOR, POSTPUBERTAL TYPE  Left: A pure tumor from an adult patient...
Published: 01 August 2022
YOLK SAC TUMOR, POSTPUBERTAL TYPE Figure 4-108 YOLK SAC TUMOR, POSTPUBERTAL TYPE Left: A pure tumor from an adult patient shows tan-brown tissue with cystic change. (Fig. 35 from Ulbright TM, Roth LM. Testicular and paratesticular tumors. In: Sternberg SS, ed. Diagnostic surgical pathology. New Y... More
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NORMAL CELLS: CYTOLOGIC PREPARATION  This preparation shows predominately S...
Published: 01 August 2022
NORMAL CELLS: CYTOLOGIC PREPARATION Figure 2-50 NORMAL CELLS: CYTOLOGIC PREPARATION This preparation shows predominately Sertoli cells with pale feathery cytoplasm, fine chromatin, and prominent nucleoli. Some contain pyknotic nuclear material. A few scattered primary spermatocytes are also prese... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-01
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... used in this Fascicle (see chapter 3 ). Despite the predominance of germ cell tumors among testicular neoplasms, those of sex cord-stromal type remain disproportionately challenging from the diagnostic and prognostic aspects. The possible relationship of some of these tumors to neoplasms at other...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... the rete testis but a müllerian-type tumor remained a diagnostic possibility. Left: Glands lined by malignant epithelium are set in a cellular, neoplastic stroma. Right: At higher magnification, the stroma shows rhabdomyosarcomatous differentiation. The predominant hypothesis of the origin of ovarian...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-05
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... Diagnosis. Differential diagnostic considerations are limited. The most pertinent and important consideration is postpubertal-type teratoma. This distinction is independent of age and pubertal status, although the majority of cases of the prepubertal and postpubertal types occur in children and young...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... Leydig cells ( 3 ), Sertoli cells, and nonspecific stromal cells of the testis. In more poorly differentiated tumors, these similarities are generally less conspicuous, but the patterns of differentiation, such as tubular, that are usually focally present are diagnostic clues. Leydig cell tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-09
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... the epididymis. Ultrasonography may show hypoechogenicity, septations, increased vascularity, and palisading blood vessels, but none of these are specific for myeloid sarcoma ( 79 ). Positron emission tomography (PET) and computerized tomography (CT) may also be diagnostically useful ( 80 ). Gross Findings...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-02
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... primary spermatocytes are also present, showing round, densely staining nuclei with coarse chromatin. (Fig. 33-18A from Koss LG, Melamed MR. The prostate and the testis. In: Koss LG, Melamed MR, eds. Koss’ diagnostic cytology and its histologic bases. Philadelphia: Lippincott Williams & Wilkins; 2006...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... of nuclei within neoplastic islands such that nuclei are separated from each other by roughly equivalent amounts of cytoplasm ( figs. 4-46A , 4-47 ), in contrast to the overlapping nuclei of embryonal carcinoma. In adequately fixed specimens, a useful diagnostic feature of many cases are the distinctly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-10
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... ). The diagnostic problems posed by testicular metastases are enhanced when the testicular tumor is the initial clinical presentation and there is concern for a primary neoplasm. In this circumstance, bilateral involvement, a feature that normally favors metastasis, is seen in only 8 percent of cases ( 7 ), whereas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-07
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... and immunohistochemical differences between gonadal maturation delay and early germ cell neoplasia in patients with undervirilization syndromes . J Clin Endocrinol Metab   2005 ; 90 : 5295 - 303 . 27. Stoop   H , Honecker   F , van de Geijn   GJ , et al . Stem cell factor as a novel diagnostic marker...