Search Results for diagnostic

RHINOSCLEROMA Figure 1-14 RHINOSCLEROMA A: The diagnostic microscopic finding of rhinoscleroma is the “Mikülicz cell,” large histiocytes with ample clear, vacuolated cytoplasm. B: Rod-shaped bacilli are demonstrated by Warthin-Starry staining. More about this image found in RHINOSCLEROMA A: The diagnostic microscopic finding of rhinoscleroma is th...

ADENOMATOID ODONTOGENIC TUMOR Figure 5-65 ADENOMATOID ODONTOGENIC TUMOR Diagnostic areas of nodular swirls of epithelium with duct-like spaces. More about this image found in ADENOMATOID ODONTOGENIC TUMOR Diagnostic areas of nodular swirls of epithe...

ODONTOGENIC KERATOCYST Figure 5-151 ODONTOGENIC KERATOCYST Diagnostic features of odontogenic keratocyst: the basal cells are palisaded and hyperchromatic, and range from cuboidal to columnar, with luminal corrugated parakeratin. There can be some limited reverse nuclear polarity. More about this image found in ODONTOGENIC KERATOCYST Diagnostic features of odontogenic keratocyst: the ...

CALCIFYING ODONTOGENIC CYST Figure 5-176 CALCIFYING ODONTOGENIC CYST The diagnostic ghost cells are enlarged, and ovoid to more elongated. They retain cellular outlines and have characteristic nuclei displaying karyolysis. More about this image found in CALCIFYING ODONTOGENIC CYST The diagnostic ghost cells are enlarged, and o...

CEMENTOBLASTOMA Figure 5-114 CEMENTOBLASTOMA “Active” areas of cementoblastoma with hypercellularity and immature matrix, suggesting the diagnostic possibility of osteosarcoma. More about this image found in CEMENTOBLASTOMA “Active” areas of cementoblastoma with hypercellularity an...

DESMOPLASTIC AMELOBLASTOMA Figure 5-49 DESMOPLASTIC AMELOBLASTOMA The tumor is characterized by a desmoplastic stromal response, compression of the tumor islands, and loss of diagnostic ameloblastic features. More about this image found in DESMOPLASTIC AMELOBLASTOMA The tumor is characterized by a desmoplastic st...

ODONTOGENIC KERATOCYST Figure 5-152 ODONTOGENIC KERATOCYST The cyst on the left merges with significant inflammation below to produce reactive changes and the loss of diagnostic features of odontogenic keratocyst. More about this image found in ODONTOGENIC KERATOCYST The cyst on the left merges with significant inflam...

NASOPHARYNGEAL ANGIOFIBROMA: SUBTRACTION ANGIOGRAM Figure 3-26 NASOPHARYNGEAL ANGIOFIBROMA: SUBTRACTION ANGIOGRAM The intense vascularity of this angiofibroma is evident in a subtraction angiogram. This finding is virtually diagnostic, and allows planning for surgery and embolization. More about this image found in NASOPHARYNGEAL ANGIOFIBROMA: SUBTRACTION ANGIOGRAM The intense vascularity...

NUT CARCINOMA Figure 1-35 NUT CARCINOMA A: Rounded, anastomosing nests of nonkeratinizing cells invade sinonasal submucosa. B: Nuclear monotony is typical, and abrupt keratinization is a useful diagnostic clue, seen in about a third of cases. More about this image found in NUT CARCINOMA A: Rounded, anastomosing nests of nonkeratinizing cells inva...

ALVEOLAR RHABDOMYOSARCOMA Figure 1-122 ALVEOLAR RHABDOMYOSARCOMA Desmin (A) and myogenin (B) are diffusely positive. Aberrant staining for other markers, such as CD56 (C) and S-100 protein (D) is common, and can present a significant diagnostic pitfall. More about this image found in ALVEOLAR RHABDOMYOSARCOMA Desmin (A) and myogenin (B) are diffusely positi...

SCLEROSING PARAGANGLIOMA Figure 7-9 SCLEROSING PARAGANGLIOMA Some paragangliomas have dense, collagenized stroma relative to the amount of actual tumor cells. This can lead to diagnostic challenges given the similarity to other lesions. The stroma obscures the typical nested pattern More about this image found in SCLEROSING PARAGANGLIOMA Some paragangliomas have dense, collagenized stro...

is typically focal or negative. D: Loss of expression of H3K27me3 is a useful diagnostic adjunct. More about this image found in MALIGNANT PERIPHERAL NERVE SHEATH TUMOR A: Alternating light and dark zone...

SMARCB1-DEFICIENT SINONASAL CARCINOMA Figure 1-37 SMARCB1-DEFICIENT SINONASAL CARCINOMA A: The tumor is an infiltrative epithelioid proliferation of undifferentiated-appearing cells. B: Empty vacuoles are often seen, which can be a helpful diagnostic clue. C: The tumor cells have More about this image found in SMARCB1-DEFICIENT SINONASAL CARCINOMA A: The tumor is an infiltrative epit...