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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... enlarge and acquire pale cytoplasm. They are most likely future chromaffin cells. A pseudorosette (Homer Wright rosette), which can be a normal developmental finding, is present in the developing sympathetic plexus (black arrow). PROVISIONAL ADRENAL CORTEX WITH MEDULLARY PROGENITORS Figure 1-10...
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Figure 9-1
Published: 01 December 2024
SITES OF PARAGANGLIOMA DEVELOPMENT Figure 9-1 SITES OF PARAGANGLIOMA DEVELOPMENT The relationship between the distribution of extra-adrenal chromaffin tissue in neonates (A) and prevalent sites of sympathetic paragangliomas reported up to 1965 (B) in a classic illustration. Arrow added More about this image found in SITES OF PARAGANGLIOMA DEVELOPMENT The relationship between the distributi...
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Figure 1-9
Published: 01 December 2024
MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Figure 1-9 MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Coronal section of fetal adrenal gland shows close association with developing sympathetic plexus (on far left). Small nests of primitive sympathetic cells (white arrows More about this image found in MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Coronal section o...
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Figure 1-11
Published: 01 December 2024
NEUROBLASTIC NODULES AND MATURING MEDULLARY PROGENITORS IN DEVELOPING FETAL ADRENAL GLAND Figure 1-11 NEUROBLASTIC NODULES AND MATURING MEDULLARY PROGENITORS IN DEVELOPING FETAL ADRENAL GLAND Fetal cortex with interspersed aggregates of immature cells with varied sizes and cytologic features More about this image found in NEUROBLASTIC NODULES AND MATURING MEDULLARY PROGENITORS IN DEVELOPING FETAL...
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Figure 1-13
Published: 01 December 2024
TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Figure 1-13 TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Most of the medullary progenitor cells in this image express TH. Because TH is a cytosolic enzyme, it can often detect ability to produce catecholamines in immature or poorly More about this image found in TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Most of the medulla...
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Figure 1-14
Published: 01 December 2024
S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Figure 1-14 S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Some S-100 protein-positive cells are present at the periphery of a small neuroblastic aggregate (right), while others are associated with scattered more mature-appearing cells with clear More about this image found in S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Some S-100 protein-positiv...
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Figure 9-4
Published: 01 December 2024
ABDOMINAL PARAGANGLIA AND ADJACENT DEVELOPING ADRENAL GLAND Figure 9-4 ABDOMINAL PARAGANGLIA AND ADJACENT DEVELOPING ADRENAL GLAND A: Normal paraganglia are fully formed before the adrenal medulla exists. This adrenal gland shows only provisional cortex and a small cluster of primitive adrenal More about this image found in ABDOMINAL PARAGANGLIA AND ADJACENT DEVELOPING ADRENAL GLAND A: Normal para...
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Figure 9-7
Published: 01 December 2024
NORMAL CAROTID BODY Figure 9-7 NORMAL CAROTID BODY A: This developing carotid body in an early second trimester stillborn fetus (same case as in figs. 9-3 and 9-4 ), shows more complex architecture and greater admixture of cell types than the abdominal paraganglia. B: Tyrosine hydroxylase More about this image found in NORMAL CAROTID BODY A: This developing carotid body in an early second tri...
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Figure 12-8
Published: 01 December 2024
ADRENAL HEMANGIOMA Figure 12-8 ADRENAL HEMANGIOMA The well-developed features of anastomosing adrenal hemangioma include a prominent frame work of non endothelial supporting cells creating a “spleen-like” pattern of vascular channels lined by hobnail endothelial cells and containing occasional More about this image found in ADRENAL HEMANGIOMA The well-developed features of anastomosing adrenal hem...
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Figure 12-10
Published: 01 December 2024
PRIMARY ADRENAL ANGIOSARCOMA Figure 12-10 PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative architecture with sinusoidal growth between cords of vacuolated cortical cells. Acute inflammatory cells and eosinophils are also present. B: Primary adrenal angiosarcoma (same case More about this image found in PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative arch...
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Figure 1-6
Published: 01 December 2024
ANATOMIC RELATIONSHIPS OF FETAL ADRENAL GLANDS Figure 1-6 ANATOMIC RELATIONSHIPS OF FETAL ADRENAL GLANDS Transverse section of upper abdomen in a fetus of about 10 weeks’ gestational age. Liver is at the top left side of the image, pancreas at top right. The developing para-aortic and preaortic More about this image found in ANATOMIC RELATIONSHIPS OF FETAL ADRENAL GLANDS Transverse section of upper...
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Figure 1-5
Published: 01 December 2024
FETAL ADRENAL GLAND AND KIDNEY Figure 1-5 FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjacent tissue from a fetus at approximately 11 weeks’ gestational age. The developing para-aortic sympathetic plexus has a close relationship with the medial and inferior aspects More about this image found in FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjac...
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Figure 2-18
Published: 01 December 2024
and hemorrhagic regressing fetal or provisional cortex. B: Developing adult cortex at left of field, with fetal cortex at right. At this early stage in postnatal life, fetal cortex is undergoing normal regression. C: Marked adrenal cytomegaly involves cells of the fetal, or provisional, cor tex. Nucleomegaly More about this image found in BECKWITH-WIEDEMANN SYNDROME A: Transverse sections of adrenal gland from a...
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Figure 9-5
Published: 01 December 2024
NORMAL ABDOMINAL PARAGANGLION Figure 9-5 NORMAL ABDOMINAL PARAGANGLION A: Low magnification shows proximity of this paraganglion to adjacent developing ganglia, adrenal gland, and kidney in a mid-second trimester fetus. B: Higher magnification of paraganglion in a mid-second trimester fetus More about this image found in NORMAL ABDOMINAL PARAGANGLION A: Low magnification shows proximity of this...
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Figure 8-47
Published: 01 December 2024
PHEOCHROMOCYTOMA: ANGIOINVASION Figure 8-47 PHEOCHROMOCYTOMA: ANGIOINVASION A,B: The presence of vascular invasion is a worrisome finding, but unlike in other neoplasms, it is not reliably associated with the development of metastatic disease. More about this image found in PHEOCHROMOCYTOMA: ANGIOINVASION A,B: The presence of vascular invasion is ...
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Figure 9-20
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-20 CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsule and tumor blood vessels. The presence of hemosiderin suggests repeated ischemia and infarction as possible factors contributing to the development of sclerosis in this case. More about this image found in CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsul...
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Figure 1-50
Published: 01 December 2024
STEROIDOGENIC FACTOR 1 (SF1) IN NORMAL ADRENAL CORTEX Figure 1-50 STEROIDOGENIC FACTOR 1 (SF1) IN NORMAL ADRENAL CORTEX SF1 controls the development of steroidogenic cells in the adrenal cortex and gonads, and distinguishes adrenal cortex from medulla. More about this image found in STEROIDOGENIC FACTOR 1 (SF1) IN NORMAL ADRENAL CORTEX SF1 controls the dev...
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Figure 1-26
Published: 01 December 2024
POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX Figure 1-26 POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX This 3-week postnatal adrenal gland shows necrosis and debris in the central part of the gland and a small amount of residual provisional cortex beneath the developing zona More about this image found in POSTNATAL REGRESSION OF PROVISIONAL ADRENAL CORTEX This 3-week postnatal a...
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Figure 2-19
Published: 01 December 2024
BECKWITH-WIEDEMANN SYNDROME Figure 2-19 BECKWITH-WIEDEMANN SYNDROME Chromaffin cells forming a nodule protruding from the fetal cortex are inappropriately mature for this stage of development and have clear cytoplasm. There is a morphologic resemblance of the nodule to normal extra-adrenal More about this image found in BECKWITH-WIEDEMANN SYNDROME Chromaffin cells forming a nodule protruding f...
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