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COMMON BLUE NEVUS  There is a small collection of fusiform and <span class="search-highlight">dendritic</span> me...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-2 COMMON BLUE NEVUS There is a small collection of fusiform and dendritic melanocytes with a few melanophages in the superficial reticular dermis. More about this image found in COMMON BLUE NEVUS There is a small collection of fusiform and dendritic me...
Images
COMMON BLUE NEVUS  Small lesion of pigmented fusiform and <span class="search-highlight">dendritic</span> melanoc...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-3 COMMON BLUE NEVUS Small lesion of pigmented fusiform and dendritic melanocytes and scattered melanophages. These cells are present in the superficial reticular dermis in association with pilar erector smooth muscle bundles. More about this image found in COMMON BLUE NEVUS Small lesion of pigmented fusiform and dendritic melanoc...
Images
COMMON BLUE NEVUS  A: Papular exophytic silhouette of a pigmented intraderm...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-6 COMMON BLUE NEVUS A: Papular exophytic silhouette of a pigmented intradermal melanocytic nevus. B: Slender fusiform and dendritic melanocytes wrap around collagen bundles. C: Dendritic melanocytes carry fine melanin granules in the cytoplasm in contrast to the large... More about this image found in COMMON BLUE NEVUS A: Papular exophytic silhouette of a pigmented intraderm...
Images
PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE  A: Diffuse involvement of t...
Published: 01 February 2024
PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE Figure 8-23 PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of the stroma of the breast by pigmented melanocytes. B: The melanocytes display spindle, epithelioid, and dendritic features and are cytologically bland. More about this image found in PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of t...
Images
ACRAL MELANOMA  A: There is a large pigmented patch on the heel.  B: There ...
Published: 01 February 2024
ACRAL MELANOMA Figure 14-1 ACRAL MELANOMA A: There is a large pigmented patch on the heel. B: There is a proliferation of predominantly solitary units of melanocytes at the dermoepidermal junction and focally above. It is associated with junctional hyperpigmentation. C: Some of the melanocytes ... More about this image found in ACRAL MELANOMA A: There is a large pigmented patch on the heel. B: There ...
Images
BLUE NEVUS WITH EPITHELIOID CELL FEATURES  A: Heavily pigmented intradermal...
Published: 01 February 2024
BLUE NEVUS WITH EPITHELIOID CELL FEATURES Figure 8-10 BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal melanocytic nevus. B,C: Most of the pigmented tumor cells are epithelioid in appearance. A minor population of melanocytes displays conventional BN-like fusiform and d... More about this image found in BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal...
Images
COMBINED BLUE NEVUS  A: Intradermal melanocytic nevus with a superficial de...
Published: 01 February 2024
COMBINED BLUE NEVUS Figure 10-10 COMBINED BLUE NEVUS A: Intradermal melanocytic nevus with a superficial dermal population of small epithelioid melanocytes (arrow) overlying a proliferation of pigmented fusiform and dendritic cells (*). B: Juxtaposition of conventional small epithelioid melanocy... More about this image found in COMBINED BLUE NEVUS A: Intradermal melanocytic nevus with a superficial de...
Images
CELLULAR BLUE NEVUS  A: Pigmented melanocytic nevus with fibrotic bulbous t...
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-13 CELLULAR BLUE NEVUS A: Pigmented melanocytic nevus with fibrotic bulbous tongue-like extensions into the subcutis. Hypercellular nodules are present in the deep portion of the tumor. B: Densely cellular spindle cell nodule is surrounded by heavily pigmented fusifo... More about this image found in CELLULAR BLUE NEVUS A: Pigmented melanocytic nevus with fibrotic bulbous t...
Images
ACRAL LENTIGINOUS MELANOMA IN SITU  There is a slight increase in the densi...
Published: 01 February 2024
ACRAL LENTIGINOUS MELANOMA IN SITU Figure 14-4 ACRAL LENTIGINOUS MELANOMA IN SITU There is a slight increase in the density of junctional melanocytes, but no confluency. The melanocytes are displayed as solitary units. Some of their nuclei are hyperchromatic and have irregular shapes (white arrow... More about this image found in ACRAL LENTIGINOUS MELANOMA IN SITU There is a slight increase in the densi...
Images
MELANOMA ARISING IN ASSOCIATION WITH A NEVUS OF OTA  A: A large, densely ce...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A NEVUS OF OTA Figure 18-2 MELANOMA ARISING IN ASSOCIATION WITH A NEVUS OF OTA A: A large, densely cellular nodule (*) is present. Its surrounding soft tissue contains variably cellular foci of blue nevus-like melanocyte aggregates. B: Atypical large epitheli... More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A NEVUS OF OTA A: A large, densely ce...
Images
MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS  A: A nodule of epithelio...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS Figure 18-1 MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelioid melanocytes is associated with melanophages as well as pigmented slender and dendritic melanocytes in the surrounding dermis. B,C: The epithelioid melanocytes display nuclear atypia (B) and lack nuclear expression of BAP1 (C), which is retained in melanophages and stromal cells. D: The epithelioid melanocytes diffusely express PRAME (preferentially expressed antigen in melanoma). The tumor carried a GNAQ 209L mutation. More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelio...
Images
MELANOMA ASSOCIATED WITH A PLAQUE BLUE NEVUS  A: Large, heavily pigmented t...
Published: 01 February 2024
MELANOMA ASSOCIATED WITH A PLAQUE BLUE NEVUS Figure 18-3 MELANOMA ASSOCIATED WITH A PLAQUE BLUE NEVUS A: Large, heavily pigmented tumor is composed of spindle and epithelioid melanocytes with areas of necrosis. B: Cytology of the tumor cells. C: The melanoma nodule (*) is located near a cellula... More about this image found in MELANOMA ASSOCIATED WITH A PLAQUE BLUE NEVUS A: Large, heavily pigmented t...
Images
MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS  A: There is an expansile ag...
Published: 01 February 2024
MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS Figure 18-5 MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS A: There is an expansile aggregate of large epithelioid melanocytes in the superficial dermis (arrow), surrounded by paucicellular fibrous tissue. This is above a more cellular pigmented prol... More about this image found in MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS A: There is an expansile ag...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and dendritic melanocytes with variable amounts of finely granular melanin pigment. The melanocytes are typically confined to the dermis and/or subcutis, with no associated intraepidermal or intrafollicular tumor component. BN shares with most other nevi immunoreactivity for MART1/Melan-A, SOX10, and tyrosinase...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Pigmented epithelioid melanocytoma (PEM) is a heavily pigmented melanocytic tumor composed of large epithelioid, fusiform, and dendritic melanocytes admixed with macrophages ( 1 , 2 ). Prior to the introduction of the term PEM, tumors with similar features were reported as “animal-type...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... IN ASSOCIATION WITH A BLUE NEVUS A: A nodule of epithelioid melanocytes is associated with melanophages as well as pigmented slender and dendritic melanocytes in the surrounding dermis. B,C: The epithelioid melanocytes display nuclear atypia (B) and lack nuclear expression of BAP1 (C), which is retained...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... melanocytes (small and large), including the melanocytes of junctional nests (arrow), lack nuclear BAP1 expression. Combined Blue Nevus. When a blue nevus is associated with a conventional nevus, the population of fusiform and dendritic melanocytes may be intimately admixed, adjacent to or located underneath...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-14
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...: There is a proliferation of predominantly solitary units of melanocytes at the dermoepidermal junction and focally above. It is associated with junctional hyperpigmentation. C: Some of the melanocytes display pigmented dendritic processes. The nuclei of the melanocytes are enlarged. SUBUNGUAL MELANOMA Figure 14-2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Mart1/Melan-A and tyrosinase are sensitive markers to visualize intraepidermal melanocytes, experience is necessary when interpreting these stains to avoid overestimating the number of true melanocytes: dendritic processes from melanocytes wrapped around keratinocytes may seem to decorate the latter...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and the superficial portion of a hair follicle. The melanocytes within the epidermis and superficial dermis are often enlarged and have an epithelioid morphology, including abundant cytoplasm, vesicular chromatin, and prominent nucleoli ( 6 ), but occasionally, melanocytes are elongated or dendritic and show...