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Figure 4-59

MUCOSAL MELANOMA A: There is strong and diffuse nuclear staining for SOX10...

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in Oral Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
MUCOSAL MELANOMA Figure 4-59 MUCOSAL MELANOMA A: There is strong and diffuse nuclear staining for SOX10. B: MART 1 (Melan-A103) shows variably reactive cytoplasmic staining. C: HMB-45 cytoplasmic staining highlights the radial growth phase, similar to lentiginous cutaneous melanoma. D: Strong More about this image found in MUCOSAL MELANOMA A: There is strong and diffuse nuclear staining for SOX10...
Book Chapter

Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... confusion when encountered in the external ear, are also discussed. Benign cutaneous lesions that may involve the skin surface of the external auricle but are commonly found on other skin surfaces, such as actinic keratosis and keratoacanthoma, are thoroughly detailed in other Fascicles and are not covered...
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Oral Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... with human immunodeficiency virus (HIV) disease, and bone marrow and solid organ transplant is also strongly linked to both cutaneous SCC and OSCC ( 3 , 13 ). A family history of head and neck cancer and some inherited genetic mutations are associated with a higher risk of oral cancer development including...
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Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... DEK::AFF2 carcinoma is a diagnostic consideration (see below); demonstrating EGFR mutation or low-risk HPV effectively excludes this emerging entity. Differential Diagnosis. Several lesions may be confused with SPs. ESP is distinguished from cutaneous squamous papilloma...
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Book Chapter

Neck

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... midline and show a granular layer and peripheral cutaneous adnexal structures associated with the wall ( 76 , 77 ). The most important differential diagnostic consideration with branchial cleft cyst is cystic metastatic SCC. This might be considered difficult, however, in practice, for most cystic neck...
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Nasopharynx

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-3
ISBN: 978-1-933477-61-9
... cutaneous adnexal structures. They arise in the nasopharynx or other upper aerodigestive tract sites. General Features. Hairy polyps are typically congenital, exophytic lesions that have been referred to by a variety of names (dermoid, teratoma, hamartoma, and choristoma) ( 12 ), although given...
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Hypopharynx, Larynx, and Trachea

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... . Oral adenoid squamous cell carcinoma: a report of three cases and review of the literature . J Oral Maxillofac Surg   1993 ; 51 : 676 - 81 . 208. Nappi   O , Pettinato   G , Wick   MR . Adenoid (acantholytic) squamous cell carcinoma of the skin . J Cutan Pathol   1989 ; 16 : 114 - 21...
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Book Chapter

Jaw

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
.... Gnathic FD affects the maxilla more often than the mandible ( 398 , 805 ). Polyostotic FD can be a component of McCune-Albright syndrome associated with cutaneous pigmentation and hyperfunctioning endocrinopathies. Mazabraud syndrome is associated with intramuscular myxomas and can occur...
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Images
Figure 4-22

COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pi...

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in Adrenal Cortical Nodular Diseases > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION Figure 4-22 COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pigmented lesions about the mouth. The patient also had a darkly pigmented lesion on the vulva, probably a blue nevus. B: Cutaneous myxoma on the breast of the same More about this image found in COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pi...
Images
Figure 12-9

JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of ...

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in Other Adrenal Neoplasms and Tumor-Like Lesions > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA Figure 12-9 JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of the adrenal gland in a newborn. There were numerous cutaneous hemangiomas and a large vascular tumor of the liver with identical histology. The adrenal tumor is uniformly More about this image found in JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of ...
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Figure 1-8

CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION A: Neural crest cells direc...

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in Physiology, Development, and Anatomy of the Adrenal Glands > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION Figure 1-8 CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION A: Neural crest cells directly migrate laterally and ventrally to give rise to cutaneous melanocytes and sympathetic ganglia (SG). B: Slightly later in embryogenesis a different group More about this image found in CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION A: Neural crest cells direc...
Book Chapter

Hereditary Predisposition to Adrenal Cortical Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... adenoma, thyroid carcinoma Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) FH Primary macronodular adrenal disease (adenoma and carcinoma in case reports) <1% Multiple cutaneous leiomyomas, uterine leiomyoma, papillary renal cell carcinoma, pheochromocytoma Birt-Hogg-Dube...
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Book Chapter

Familial and Syndrome-Related Pheochromocytoma and Paraganglioma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... neuroendocrine tumor SDHAF2 11q12.2 PGL2 (paraganglioma type 2) Head and neck 1 Unknown FH 1q42.1 HLRCC (hereditary leiomyomatosis and renal cell carcinoma) Adrenal and extra-adrenal 1 Cutaneous and uterine leiomyomas Renal cell carcinoma MDH2 7q11.23 Abdominal...
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Book Chapter

Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and containing occasional fibrin thrombi. A small amount of residual adrenal cortex is present at right. JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA Figure 12-9 JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of the adrenal gland in a newborn. There were numerous cutaneous hemangiomas...
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Book Chapter

Paraganglia and Paragangliomas

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in parasympathetic paraganglia are also known as “type 1” cells, “chief cells,” or “glomus cells,” and the sustentacular cells are also known as “type 2 cells.” “Glomus” is discouraged in pathology literature because the same name applies to cutaneous temperature sensors and their corresponding tumors, but it still...
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Book Chapter

Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... PIGMENTATION Figure 4-22 COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pigmented lesions about the mouth. The patient also had a darkly pigmented lesion on the vulva, probably a blue nevus. B: Cutaneous myxoma on the breast of the same patient, who also had a cardiac myxoma...
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Book Chapter

Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... . Central pancreatectomy for a pancreatic ganglioneuroma in a patient with previous neuroblastoma . Pancreatology   2002 ; 2 : 557 - 60 . 109. Wallace   CA , Hallman   JR , Sangueza   OP . Primary cutaneous ganglioneuroma: a report of two cases and literature review . Am J Dermatopathol...
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Book Chapter

Physiology, Development, and Anatomy of the Adrenal Glands

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cells directly migrate laterally and ventrally to give rise to cutaneous melanocytes and sympathetic ganglia (SG). B: Slightly later in embryogenesis a different group of neural crest-derived cells migrates from the dorsal route ganglia (DRG) along sensory axons to reach preganglionic sympathetic axons...
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Book Chapter

Adrenal Cortical Carcinoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of patients had a history of other malignancies and 3 percent developed other malignancies after ACC diagnosis ( 8 ). Associated malignancies were extremely variable, including different types of carcinomas (prostate, bladder, lung, thyroid gland, breast, endometrial, cervical, renal, cutaneous non...
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Images
Figure 12-22

CUTANEOUS NOCARDIOSIS Clinical features of primary cutaneous nocardiosis (...

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in Respiratory Tract > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
CUTANEOUS NOCARDIOSIS Figure 12-22 CUTANEOUS NOCARDIOSIS Clinical features of primary cutaneous nocardiosis (A), including Nocardia (bacterial) “mycetoma” (B). (Courtesy of the CDC PHIL) More about this image found in CUTANEOUS NOCARDIOSIS Clinical features of primary cutaneous nocardiosis (...