CORE NEEDLE BIOPSY SPECIMENS Figure 15-1 CORE NEEDLE BIOPSY SPECIMENS Side by side comparison of a 14G core needle sample and an 8G core needle sample. More about this image found in CORE NEEDLE BIOPSY SPECIMENS Side by side comparison of a 14G core needle ...

ROSAI-DORFMAN DISEASE Figure 2-4 ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fibrous breast parenchyma with a mixed chronic inflammatory cell infiltrate. B: Higher power reveals the presence of histiocytes, lymphocytes, and plasma cells. C: High power shows a histioc... More about this image found in ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fi...

POLYACRYLAMIDE HYDROGEL Figure 2-15 POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with pools of bluish material and calcifications present in the adipose tissue. B: On higher power, giant cells can be seen associated with the “mucin-like” material. Note the absence of epithe... More about this image found in POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with po...

CYST WALL Figure 2-20 CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of the cyst wall and the attenuated epithelial lining, particularly where it runs along the edges of the core biopsy sample. More about this image found in CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of...

STROMAL REACTION TO RUPTURED CYST Figure 2-21 STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows fibroadipose tissue with a chronic inflammatory cell infiltrate and stromal fibrosis. B: High-power view demonstrates histiocytes, lymphocytes, and plasma cells; while not defin... More about this image found in STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows f...

LOBULAR CARCINOMA IN SITU WITH NECROSIS Figure 4-19 LOBULAR CARCINOMA IN SITU WITH NECROSIS A: This core needle biopsy was performed because of mammographically detected microcalcifications. The hematoxylin and eosin (H&E) image depicts acini greatly expanded by an atypical epithelial prolife... More about this image found in LOBULAR CARCINOMA IN SITU WITH NECROSIS A: This core needle biopsy was per...

FIBROADENOMA: PERICANALICULAR PATTERN Figure 5-4 FIBROADENOMA: PERICANALICULAR PATTERN A: At low power, this core needle biopsy specimen of a benign stromal and epithelial tumor has numerous glands with more open rounded lumens compared with the compressed ducts of a fibroadenoma with an intracan... More about this image found in FIBROADENOMA: PERICANALICULAR PATTERN A: At low power, this core needle bi...

FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY Figure 5-35 FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY A: This core needle biopsy specimen shows a fibroepithelial lesion with a variable increase in stromal cellularity. The cores have fragmented into multiple pieces, which... More about this image found in FIBROEPITHELIAL LESION WITH INCREASED STROMAL CELLULARITY A: This core nee...

MALIGNANT PHYLLODES TUMOR Figure 5-36 MALIGNANT PHYLLODES TUMOR A: At low power, this core needle biopsy appears to be composed entirely of spindle cells. The lesion is hypercellular. The tissue fragment at upper right has a focus of benign-appearing epithelium (arrow). B: Higher power shows the... More about this image found in MALIGNANT PHYLLODES TUMOR A: At low power, this core needle biopsy appears...

PHYLLODES TUMOR Figure 5-37 PHYLLODES TUMOR A: This core needle biopsy specimen highlights the extreme variability that can be seen in phyllodes tumor, with the area on the right bearing greater resemblance to fibroadenoma, and that on the lower left, malignant phyllodes tumor. B,C: High power o... More about this image found in PHYLLODES TUMOR A: This core needle biopsy specimen highlights the extreme...

TUBULAR ADENOMA Figure 5-40 TUBULAR ADENOMA A: This core biopsy shows a well-circumscribed aggregate of tightly packed glands. B: Higher power reveals the benign-appearing compacted glands. More about this image found in TUBULAR ADENOMA A: This core biopsy shows a well-circumscribed aggregate o...

LACTATING ADENOMA Figure 5-42 LACTATING ADENOMA A: At low power, this core needle biopsy illustrates a circumscribed mass composed of expanded terminal duct lobular units (TDLUs). B: At high power, the cells within the acini of the TDLU have the vacuolated cytoplasm characteristic of secretory o... More about this image found in LACTATING ADENOMA A: At low power, this core needle biopsy illustrates a c...

MICROGLANDULAR ADENOSIS Figure 6-21 MICROGLANDULAR ADENOSIS A: On core needle biopsy, microglandular adenosis may be misinterpreted as a low-grade invasive ductal carcinoma. B: The growth pattern and lack of myoepithelial cells do not differentiate one diagnosis over the other. The eosinophilic ... More about this image found in MICROGLANDULAR ADENOSIS A: On core needle biopsy, microglandular adenosis ...

RADIAL SCAR Figure 6-27 RADIAL SCAR A: Core needle biopsy of a radial scar shows most of the central nidus and the radiating epithelial elements. B: Intermediate-power view illustrates the glandular/ductal distortion that can occur in the area of elastosis. C: High power of the stromal elastosi... More about this image found in RADIAL SCAR A: Core needle biopsy of a radial scar shows most of the centr...