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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...There are numerous inflammatory and reactive processes that involve the breast. Many of these are processes, or are in response to conditions, that may occur in any organ of the body and have similar morphologic features to those same diseases elsewhere. However, there are some entities...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-01
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... of keratinocytes is seen in many other conditions, which are clinically distinct and rarely prompt a biopsy for diagnostic confirmation. They include Becker nevus (hyperpigmentation associated with hypertrichosis and smooth muscle hamartoma), melisma, the pigmented macules of Albright syndrome (associated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... will also likely be more conditional and dynamic for use along the clinical journey of the patient and not just at its outset. REPORTING OF PRIMARY CUTANEOUS MELANOMA Reporting Content A pathology report of melanoma should include all information that is needed for clinical care. The most important part...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Hutchinson melanotic freckle. Dubreuilh reported a series of patients with similar findings and named the condition “lentigo malin des viellards” and “la melanose circonsrite precancereuse,” giving rise to the term “circumscribed precancerous melanosis of Dubreuilh.” Dubreuilh already recognized that LM may...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... as of the trigeminal nerve (periorbital region, forehead, temple, cheek, and nose), as well as conjunctiva, retina, periorbital soft tissue, and nasal mucosa. The condition usually presents unilaterally at birth or in childhood, but delayed onset in adolescence may occur. Approximately 0.01 to 0.03 percent of Asians...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
..., intraductal papilloma, columnar cell lesions, cysts and pseudoangiomatous stromal hyperplasia ( 1 ). Reported rates of atypia are low ( 2 ). GYNECOMASTIA Definition.  Gynecomastia is a common condition characterized by increasing breast size, which may be either unilateral or bilateral, and can...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... affect postpubertal girls. The condition is extremely debilitating, causing back and neck pain, as well as being socially distressing. Circulating gonadal hormonal levels are normal and definitive risk factors have not been identified, although studies have hypothesized end-organ hypersensitivity...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... conditions. The first, pregnancy-like change, may be seen in one or several lobules in the absence of pregnancy or hormonal manipulation ( 28 , 29 ). The acini are dilated and the cells have abundant vacuolated cytoplasm, with large nuclei which are sometimes apically located (giving an appearance...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... of a patient with breast cancer having a lymph node metastasis. It is incumbent on the pathologist to exclude metastatic carcinoma before concluding that epithelium present in sampled axillary lymph nodes is benign. OTHER CONDITIONS Silicone Lymphadenopathy Patients with silicone breast implants are at risk...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), a condition more frequently affecting older adults. In addition to knowledge of the patient history, clues to the diagnosis of SLL are the presence of aggregates of monotonous lymphocytes that infiltrate the stroma and a relative absence of other...
Images
STRESS CARDIOMYOPATHY: APICAL BALLOONING  Left ventriculography shows dilat...
Published: 15 November 2023
STRESS CARDIOMYOPATHY: APICAL BALLOONING Figure 18-1 STRESS CARDIOMYOPATHY: APICAL BALLOONING Left ventriculography shows dilatation of the left ventricular apex, so-called “apical ballooning,” somewhat characteristic of this condition. More about this image found in STRESS CARDIOMYOPATHY: APICAL BALLOONING Left ventriculography shows dilat...
Images
CARCINOID HEART DISEASE  Fibroproliferative pads/plaques (asterisks) are ch...
Published: 15 November 2023
CARCINOID HEART DISEASE Figure 21-25 CARCINOID HEART DISEASE Fibroproliferative pads/plaques (asterisks) are characteristic of carcinoid heart disease. They are seen with both H&E (left) and Masson trichome (right) staining. The cellularity helps differentiate this condition from nonspecific ... More about this image found in CARCINOID HEART DISEASE Fibroproliferative pads/plaques (asterisks) are ch...
Images
ALKAPTONURIA  Left: The black pigment of ochronosis stains the cartilage in...
Published: 15 November 2023
ALKAPTONURIA Figure 9-31 ALKAPTONURIA Left: The black pigment of ochronosis stains the cartilage in a variety of body structures including the intervertebral discs and airway cartilage. Right: The cardiac valves often have a black discoloration, as in this aortic valve. Calcification is also com... More about this image found in ALKAPTONURIA Left: The black pigment of ochronosis stains the cartilage in...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... lymphatic spaces. Identification of dermal lymphatic invasion in resection or mastectomy specimens in the absence of the aforementioned clinical signs and symptoms should not be reported as inflammatory carcinoma. This is strictly a clinical condition and not a pathologic diagnosis. Historically, clinical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch18
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... characteristic of this condition. STRESS CARDIOMYOPATHY Figure 18-2 STRESS CARDIOMYOPATHY The prominent left ventricular dilatation is relatively diffuse, manifesting in this section at the mid-ventricular level and suggesting widespread ventricular involvement. STRESS CARDIOMYOPATHY Figure 18-3 STRESS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch19
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...., Noonan syndrome [NS]) and Marfan syndrome [MFS]). RASopathies. RASopathies are a group of conditions that result from abnormal signal transduction, which results from mutations in the genes encoding for proteins in the RAS-mitogen-activated protein kinase (MAPK) pathway ( Table 19-4...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch13
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... cardiovascular conditions using formalin-fixed paraffin-embedded tissues and dried blood spots . Circ Cardiovasc Genet   2017 ; 10 : e001844 . Anatomic/Pathologic Approaches When to Test GENETICS Cardiac Dysfunction CLASSIFICATION Combined Approaches Biopsy Autopsy Surgical Why Test? SOURCES OF TISSUE...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch21
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... (asterisks) are characteristic of carcinoid heart disease. They are seen with both H&E (left) and Masson trichome (right) staining. The cellularity helps differentiate this condition from nonspecific endocardial fibrosis. REFERENCES REFERENCES 1. Lee   JL , Naguwa   SM , Cheema   GS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch20
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... than the general population, they are still affected by this common condition: hypertension has been found in 3 percent of young (18 to 40 years) athletes, compared to 11 percent in a similarly aged cohort of the general population ( 24 , 25 ). In the presence of a clinical history of hypertension...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch28
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... reaction. The most common causes are trauma and infection, although other etiologies, such as focal pancreatic digestion of the splenic artery wall, can result in a contained rupture. Some inflammatory conditions, such as Kawasaki disease, may result in complete medial destruction with the formation...