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CLEAR CELL CARCINOMA  An ovarian endometriotic cyst containing a mural nodu...
Published: 01 August 2023
CLEAR CELL CARCINOMA Figure 6-1 CLEAR CELL CARCINOMA An ovarian endometriotic cyst containing a mural nodule (A) or several nodules (B) is a classic appearance. Some tumors are almost entirely solid in appearance (C), while occasional tumors demonstrate focal carcinoma (mural nodule in cyst at ri... More about this image found in CLEAR CELL CARCINOMA An ovarian endometriotic cyst containing a mural nodu...
Images
YOLK SAC TUMOR  A–C: Microscopically, yolk sac tumors display a wide variet...
Published: 01 August 2023
YOLK SAC TUMOR Figure 13-11 YOLK SAC TUMOR A–C: Microscopically, yolk sac tumors display a wide variety of patterns. Some are subtle, and a high index of suspicion is necessary. The photomicrographs illustrate the classic reticular-microvesicular pattern (A,B), a Schiller-Duvall body (C), with a ... More about this image found in YOLK SAC TUMOR A–C: Microscopically, yolk sac tumors display a wide variet...
Images
YOLK SAC TUMOR  A–C: Microscopically, yolk sac tumors display a wide variet...
Published: 01 August 2023
YOLK SAC TUMOR Figure 13-11 YOLK SAC TUMOR A–C: Microscopically, yolk sac tumors display a wide variety of patterns. Some are subtle, and a high index of suspicion is necessary. The photomicrographs illustrate the classic reticular-microvesicular pattern (A,B), a Schiller-Duvall body (C), with a ... More about this image found in YOLK SAC TUMOR A–C: Microscopically, yolk sac tumors display a wide variet...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-05
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... clear cells lining papillae in microcystic or solid areas. In the past, these tumors were often classified as mixed serous and clear cell carcinomas. Such neoplasms, however, do not have the classic features of clear cell carcinoma, including tubulocystic and solid areas, simple papillae often...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... cells. YOLK SAC TUMOR Figure 13-10 YOLK SAC TUMOR A–C: Gross appearance. YOLK SAC TUMOR Figure 13-11 YOLK SAC TUMOR A–C: Microscopically, yolk sac tumors display a wide variety of patterns. Some are subtle, and a high index of suspicion is necessary. The photomicrographs illustrate the classic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-06
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...CLEAR CELL CARCINOMA Figure 6-1 CLEAR CELL CARCINOMA An ovarian endometriotic cyst containing a mural nodule (A) or several nodules (B) is a classic appearance. Some tumors are almost entirely solid in appearance (C), while occasional tumors demonstrate focal carcinoma (mural nodule in cyst...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-03
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... may be lifelong. These are presented in Table 3-3 . Definition.  DICER syndrome is an autosomal dominant cancer predisposition syndrome, usually involving a germline mutation in DICER1. General and Clinical Features. The incidence is unknown. The classic triad of tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... ( 31 ). Prognosis. These tumors are typically confined to the ovary, and are benign. The tumor cells are round or polygonal. Minimal cytoplasm is characteristic of the classic “small cell” type, but areas or even entire tumors can contain tumor cells with abundant cytoplasm characteristic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-04
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...; there is no limit to the number of foci The microinvasive foci consist of individual eosinophilic cells and cell clusters (“classic” microinvasion) Serous borderline tumor with microinvasive LGSC Microinvasion is present in the primary ovarian tumor, but is <5 mm in greatest dimension; there is no limit...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-12
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... cells or a more classic Sertoli-like tubule pattern, and clear lipid vacuoles may be seen in the cytoplasm. Sporadic cases have areas resembling Sertoli cell tumors or microfollicular granulosa cell tumors. The tumor cells are columnar with pale cytoplasm and basally located round nuclei. The overall...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-15
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
.... The classic pattern is individual signet ring cells or small clusters sometimes forming small glands, lying within a reactive stroma ( 28 ). This reactive stroma shows mild pleomorphism, but the atypia is not “sarcoma-like.” The tubular pattern consists of glands with or without lumens (i.e., solid tubules...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-07
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... mitotic activity, particularly toward the luminal border of the tumor cells. Also, HPV-associated endocervical adenocarcinoma overexpresses p16 and lacks diffuse expression of ER and PR, unlike endometrioid carcinoma ( 63 , 82 ). There are a number of situations that fail to conform to the classic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-16
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... are usually elevated. Macroscopically, nearly all cases are unilateral. Historically defined fallopian tube carcinomas classically give rise to a fusiform swelling of the tube and a clinical impression of hydrosalpinx, hematosalpinx, or pyosalpinx, but small fimbrial lesions are usually not appreciated...
Images
Images
METASTATIC MALIGNANT MELANOMA  Left: The <span class="search-highlight">classic</span> histologic features includ...
Published: 01 March 2023
METASTATIC MALIGNANT MELANOMA Figure 14-10 METASTATIC MALIGNANT MELANOMA Left: The classic histologic features include a diffuse pattern and epithelioid cells with abundant cytoplasm and prominent nucleoli. Right: Other cases are noncohesive and have little cytoplasm. More about this image found in METASTATIC MALIGNANT MELANOMA Left: The classic histologic features includ...
Images
PANCREATOBLASTOMA  Treatment effects include fibrosis (left) and infiltrate...
Published: 01 March 2023
PANCREATOBLASTOMA Figure 10-16 PANCREATOBLASTOMA Treatment effects include fibrosis (left) and infiltrates of foamy histiocytes (right), which can obscure the classic histologic features. More about this image found in PANCREATOBLASTOMA Treatment effects include fibrosis (left) and infiltrate...
Images
PANCREATOBLASTOMA  In this patient with familial adenomatous polyposis (FAP...
Published: 01 March 2023
PANCREATOBLASTOMA Figure 10-13 PANCREATOBLASTOMA In this patient with familial adenomatous polyposis (FAP), a morphologically classic pancreatoblastoma (left) is present and a tubular adenoma also involves the ampulla of Vater (right). More about this image found in PANCREATOBLASTOMA In this patient with familial adenomatous polyposis (FAP...
Images
<span class="search-highlight">CLASSIC</span> HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CERVICAL INTRAEPITHELIA...
Published: 01 February 2023
CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CERVICAL INTRAEPITHELIAL NEOPLASIA 3 [CIN3]) Figure 3-9 CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CERVICAL INTRAEPITHELIAL NEOPLASIA 3 [CIN3]) Decreased maturation, full thickness atypia with hyperchromasia, and evident variation in nu... More about this image found in CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CERVICAL INTRAEPITHELIA...
Images
<span class="search-highlight">CLASSIC</span> HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN2-3)  Even though th...
Published: 01 February 2023
CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN2-3) Figure 3-10 CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN2-3) Even though the surface shows maturation in the form of more abundant cytoplasm and nuclear spacing, the entire population is atypical, with nuclear enlargement, hyp... More about this image found in CLASSIC HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN2-3) Even though th...
Images
KERATOACANTHOMA  These lesions show a <span class="search-highlight">classic</span> cup-shaped architecture with ...
Published: 01 February 2023
KERATOACANTHOMA Figure 5-3 KERATOACANTHOMA These lesions show a classic cup-shaped architecture with central keratin accumulation. The basal layer has a bland appearance. More about this image found in KERATOACANTHOMA These lesions show a classic cup-shaped architecture with ...