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<span class="search-highlight">CHRONIC</span> LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL)  A: At lo...
Published: 01 January 2024
CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) Figure 12-2 CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) A: At low power, numerous lymphocytes are seen infiltrating the breast stroma. B: A higher-power image demonstrates the monotonous appearance of the lym... More about this image found in CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) A: At lo...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... – 5 ). In mixed variants, a part of the tumor is densely cellular and lacks prominent or any fibroplasia. CLINICAL FEATURES DM accounts for less than 4 percent of all melanomas ( 6 – 9 ). It most often develops in chronically sun-damaged skin of the head and neck region of elderly Caucasians...
Images
ROSAI-DORFMAN DISEASE  A: A low-power view of a core needle biopsy shows fi...
Published: 01 January 2024
ROSAI-DORFMAN DISEASE Figure 2-4 ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fibrous breast parenchyma with a mixed chronic inflammatory cell infiltrate. B: Higher power reveals the presence of histiocytes, lymphocytes, and plasma cells. C: High power shows a histioc... More about this image found in ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fi...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Lentigo maligna melanoma (LMM) is a variant of melanoma that occurs on chronically sun-damaged skin. It is histopathologically characterized by a junctional proliferation of predominantly solitary units of melanocytes ( 1 – 4 ). The noninvasive melanoma confined to the epidermis...
Images
MAMMARY DUCT ECTASIA: EARLY STAGE  A: Low-power view demonstrates dilated d...
Published: 01 January 2024
MAMMARY DUCT ECTASIA: EARLY STAGE Figure 2-1 MAMMARY DUCT ECTASIA: EARLY STAGE A: Low-power view demonstrates dilated ducts with a surrounding chronic inflammatory cell infiltrate and luminal secretion. Histiocytes are apparent in the epithelial lining and duct lumen. B: Intermediate power shows... More about this image found in MAMMARY DUCT ECTASIA: EARLY STAGE A: Low-power view demonstrates dilated d...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... evidence of regression is a loss of melanocytes related to inflammation. A lymphocytic infiltrate typically reflects early regression. Later stages of regression are characterized by a mix of dermal fibrosis and chronic inflammation, often involving pigment-laden macrophages. The epidermis may...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-17
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in situ variants. Partial biopsies of some lesions of melanoma in situ, especially at sites of chronic sun damage (lentigo maligna melanoma) or at acral sites, may look indistinguishable from an atypical junctional nevus. Clinical context then provides compelling evidence for the correct diagnosis...
Images
GYNECOMASTIA  A: At low power, breast ducts, some with epithelial hyperplas...
Published: 01 January 2024
GYNECOMASTIA Figure 10-1 GYNECOMASTIA A: At low power, breast ducts, some with epithelial hyperplasia, are embedded in a loose, edematous stroma. B: Micropapillary usual ductal hyperplasia (UDH) is present in this duct. A few chronic inflammatory cells are present in the stroma. More about this image found in GYNECOMASTIA A: At low power, breast ducts, some with epithelial hyperplas...
Images
INVASIVE LOBULAR CARCINOMA  A: At low power, invasive lobular carcinoma wit...
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA Figure 8-35 INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma with low nuclear grade can resemble chronic inflammation. B: Higher-power examination reveals the epithelial nature of the cells as well as the characteristic cytologic features. More about this image found in INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma wit...
Images
FAT NECROSIS  Intermediate-power view of an area of fat necrosis showing ch...
Published: 01 January 2024
FAT NECROSIS Figure 2-19 FAT NECROSIS Intermediate-power view of an area of fat necrosis showing chronic inflammation, multinucleated giant cells, and histiocytes infiltrating through the fibrous parenchyma and adipose tissue. Note the presence of a cyst-like area at the lower portion of the fiel... More about this image found in FAT NECROSIS Intermediate-power view of an area of fat necrosis showing ch...
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BIOPSY SITE  Biopsy marking devices produce varying morphologic responses, ...
Published: 01 January 2024
BIOPSY SITE Figure 15-10 BIOPSY SITE Biopsy marking devices produce varying morphologic responses, but in each instance, evidence of a tissue reaction, foreign body giant cells (A), and a chronic inflammatory cell infiltrate (B), in addition to locating the clip, is important to confirm excision ... More about this image found in BIOPSY SITE Biopsy marking devices produce varying morphologic responses, ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... ; 68 : 963 - 70 . 16. Yazdan   P , Haghighat   Z , Guitart   J , Gerami   P . Epithelioid and fusiform blue nevus of chronically sun-damaged skin, an entity distinct from the epithelioid blue nevus of the Carney complex . Am J Surg Pathol   2013 ; 37 : 81 - 8 . 17. Cohen...
Images
STROMAL REACTION TO RUPTURED CYST  A: A core needle biopsy specimen shows f...
Published: 01 January 2024
STROMAL REACTION TO RUPTURED CYST Figure 2-21 STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows fibroadipose tissue with a chronic inflammatory cell infiltrate and stromal fibrosis. B: High-power view demonstrates histiocytes, lymphocytes, and plasma cells; while not defin... More about this image found in STROMAL REACTION TO RUPTURED CYST A: A core needle biopsy specimen shows f...
Images
NIPPLE ADENOMA  A: The proliferation comprising the nipple adenoma is compo...
Published: 01 January 2024
NIPPLE ADENOMA Figure 13-6 NIPPLE ADENOMA A: The proliferation comprising the nipple adenoma is composed of nests of epithelial cells embedded in a fibrotic stroma. In this case, there is also squamous metaplasia of the nipple ducts with an associated chronic inflammatory cell infiltrate. B,C: I... More about this image found in NIPPLE ADENOMA A: The proliferation comprising the nipple adenoma is compo...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., especially if associated with chronic sun-damage (located in head and neck area, presence of marked solar elastosis). IMMUNOHISTOCHEMICAL FINDINGS A number of immunohistochemical studies are useful for the assessment of spitzoid melanocytic neoplasms. Strong and diffuse labeling of all or nearly all tumor...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., focal inflammation, and a benign dermal nevus component. Scratched/Rubbed Nevus. Chronic rubbing results in epidermal hyperplasia with elongated and thickened rete ridges and thickened and vertically oriented collagen fibers within the papillary dermis. Intraepidermal and dermal hemorrhage may...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... nodal tissue sites, it is important to exclude secondary involvement by a systemic process before rendering a diagnosis of primary breast lymphoma. Given that a large proportion of breast cancer patients are postmenopausal women, it follows that some proportion of the affected patients also have chronic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... with gynecomastia. The tissue sampled appears dense, white, and fibrous. Microscopic Findings. Microscopic features vary with the stage at presentation. Early lesions show loose periductal stromal fibrosis, sometimes with an associated chronic inflammatory cell infiltrate ( fig. 10-1 ). Often there is intraductal...
Images
SPONTANEOUS CORONARY ARTERY DISSECTION: <span class="search-highlight">CHRONIC</span>  <span class="search-highlight">Chronic</span> dissections manife...
Published: 15 November 2023
SPONTANEOUS CORONARY ARTERY DISSECTION: CHRONIC Figure 6-13 SPONTANEOUS CORONARY ARTERY DISSECTION: CHRONIC Chronic dissections manifest as an area of organized fibrotic tissue with numerous vascular spaces (black asterisk), usually in the outer third of the media (where dissections are most comm... More about this image found in SPONTANEOUS CORONARY ARTERY DISSECTION: CHRONIC Chronic dissections manife...
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<span class="search-highlight">CHRONIC</span> ANEMIA: TIGERING  Endocardial mottling (“tigering”) in <span class="search-highlight">chronic</span> anem...
Published: 15 November 2023
CHRONIC ANEMIA: TIGERING Figure 21-10 CHRONIC ANEMIA: TIGERING Endocardial mottling (“tigering”) in chronic anemia is characterized by a banded mottling of the subendocardium. More about this image found in CHRONIC ANEMIA: TIGERING Endocardial mottling (“tigering”) in chronic anem...