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<span class="search-highlight">CHRONIC</span> HYDROCELE SAC  The thickened, fibrotic wall of a <span class="search-highlight">chronic</span> hydrocele,...
Published: 01 August 2022
CHRONIC HYDROCELE SAC Figure 11-42 CHRONIC HYDROCELE SAC The thickened, fibrotic wall of a chronic hydrocele, which contains fibrin in its cavity, is firmly adherent to an atrophic testis (bottom). More
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MESOTHELIAL HYPERPLASIA IN A <span class="search-highlight">CHRONIC</span> HYDROCELE  Left: The fibrotically thic...
Published: 01 August 2022
MESOTHELIAL HYPERPLASIA IN A CHRONIC HYDROCELE Figure 11-45 MESOTHELIAL HYPERPLASIA IN A CHRONIC HYDROCELE Left: The fibrotically thickened wall of a chronic hydrocele contains a band of entrapped, hyperplastic mesothelium. Granulation tissue is superficial (right) to the mesothelium. Right: The... More
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<span class="search-highlight">CHRONIC</span> EPIDIDYMO-ORCHITIS  The testis has a gelatinous consistency, with c...
Published: 01 August 2022
CHRONIC EPIDIDYMO-ORCHITIS Figure 11-110 CHRONIC EPIDIDYMO-ORCHITIS The testis has a gelatinous consistency, with cystic degeneration. Extensive fibrosis involves the epididymis and paratesticular soft tissue. More
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<span class="search-highlight">CHRONIC</span> EPIDIDYMAL ABSCESS  The abscess is surrounded by extensive fibrosis...
Published: 01 August 2022
CHRONIC EPIDIDYMAL ABSCESS Figure 11-111 CHRONIC EPIDIDYMAL ABSCESS The abscess is surrounded by extensive fibrosis, including dense fibrous adhesions to the scrotal wall (left). More
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<span class="search-highlight">CHRONIC</span> EPIDIDYMITIS  Left: A lymphoplasmacytic and histiocytic inflammator...
Published: 01 August 2022
CHRONIC EPIDIDYMITIS Figure 11-112 CHRONIC EPIDIDYMITIS Left: A lymphoplasmacytic and histiocytic inflammatory infiltrate occupies the stroma between efferent ductules containing intraluminal neutrophils and histiocytes. Right: Prominent dystrophic calcification and cystic change of epididymal t... More
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SYPHILITIC GUMMA OF TESTIS  Gummatous necrosis is bordered by a zone of fib...
Published: 01 August 2022
SYPHILITIC GUMMA OF TESTIS Figure 11-116 SYPHILITIC GUMMA OF TESTIS Gummatous necrosis is bordered by a zone of fibrous tissue that contains chronic inflammatory cells. (Fig. 9.21 from Young RH, Scully RE. Testicular tumors. Chicago: ASCP Press; 1990:209.) More
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ACQUIRED CYSTIC TRANSFORMATION OF THE RETE TESTIS  The rete testis is dilat...
Published: 01 August 2022
ACQUIRED CYSTIC TRANSFORMATION OF THE RETE TESTIS Figure 11-53 ACQUIRED CYSTIC TRANSFORMATION OF THE RETE TESTIS The rete testis is dilated and contains polarizable calcium oxalate crystals admixed with proteinaceous, eosinophilic secretion. This autopsy specimen was from a patient on chronic ren... More
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PARATESTICULAR LOCALIZED LYMPHEDEMA  Left: A discrete area of lymphedema pr...
Published: 01 August 2022
PARATESTICULAR LOCALIZED LYMPHEDEMA Figure 11-135 PARATESTICULAR LOCALIZED LYMPHEDEMA Left: A discrete area of lymphedema produces a lace-like pattern in the soft tissue with associated chronic inflammation. There was a clinical diagnosis of torsion. Right: High-power view of the lesion shows th... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., and vasculopathic changes are related to chronic intermittent torsion ( 46 ). Torsion may also induce prominent reactive changes in the paratesticular soft tissues that may cause confusion with an inflammatory myofibroblastic tumor ( fig. 11-29 ) ( 54 ). Cytoplasmic reactivity for anaplastic lymphoma kinase (ALK...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-09
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... percent) mutations are seen ( 45 , 47 ). CD79B mutations lead to chronic active B-cell receptor signaling, which in turn, results in NF-kb pathway activation. MYD88 mutations also activate the NF-kb pathway as well as JAK-STAT3 signaling ( 45 , 47 ). Both BCL6 and PDL1...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
...) that contrasts with the non-neoplastic epithelium (black arrows). The etiology is poorly understood. Several studies, however, have reported an association with different conditions and chemical exposures, including hydrocele, chronic epididymitis, cryptorchidism, carbon dioxide, lead, fire extinguishing agents...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Publisher: American Registry of Pathology
Published: 01 August 2022
DOI: 10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... ( 13a ). Sertoli cell tumor, NOS, may be potentially misdiagnosed as seminoma when it has a diffuse pattern ( 127 , 142 , 143 ). Sertoli cell tumors usually have no or only a scant nonspecific chronic inflammatory cell infiltrate, lacking the consistent sprinkling of lymphocytes that characterizes most...
Images
REACTIVE MESOTHELIAL CELLS  Left: Pericardial resection for <span class="search-highlight">chronic</span> pericar...
Published: 01 June 2022
REACTIVE MESOTHELIAL CELLS Figure 3-103 REACTIVE MESOTHELIAL CELLS Left: Pericardial resection for chronic pericarditis shows a cluster of reactive mesothelial cells within the lymphatic space. Right: D2-40 stain confirms the mesothelial nature of the intralymphatic cells. More
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DIFFUSE LARGE B-CELL LYMPHOMA ASSOCIATED WITH <span class="search-highlight">CHRONIC</span> INFLAMMATION  A: Clus...
Published: 01 June 2022
DIFFUSE LARGE B-CELL LYMPHOMA ASSOCIATED WITH CHRONIC INFLAMMATION Figure 6-4 DIFFUSE LARGE B-CELL LYMPHOMA ASSOCIATED WITH CHRONIC INFLAMMATION A: Clusters of large dyscohesive cells are present within a pleural biopsy. Necrosis is seen. B: A separate case shows large dyscohesive cells within f... More
Images
ACUTE AND <span class="search-highlight">CHRONIC</span> EFFUSION  Both neutrophils and lymphocytes are present wi...
Published: 01 June 2022
ACUTE AND CHRONIC EFFUSION Figure 8-2 ACUTE AND CHRONIC EFFUSION Both neutrophils and lymphocytes are present within proteinaceous debris. A cluster of mesothelial cells shows mild reactive atypia. More
Images
REACTIVE FIBROUS PLEURITIS  Left: The surface is replaced by <span class="search-highlight">chronically</span> in...
Published: 01 June 2022
REACTIVE FIBROUS PLEURITIS Figure 8-4 REACTIVE FIBROUS PLEURITIS Left: The surface is replaced by chronically inflamed granulation tissue and fibrin, with loose fibroblastic tissue that matures to denser, more established fibrosis away from the surface. As is often the case, there is a linear chr... More
Images
MESOTHELIAL CELLS:PHAGOCYTOSIS  Top: Hemosiderin pigment is seen within the...
Published: 01 June 2022
MESOTHELIAL CELLS:PHAGOCYTOSIS Figure 1-8 MESOTHELIAL CELLS:PHAGOCYTOSIS Top: Hemosiderin pigment is seen within the mesothelial cells on the surface of chronically inflamed pleura. Bottom: Calretinin staining confirms mesothelial origin. More
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PLEURAL AMYLOIDOSIS  The pleura contains acellular eosinophilic material th...
Published: 01 June 2022
PLEURAL AMYLOIDOSIS Figure 8-16 PLEURAL AMYLOIDOSIS The pleura contains acellular eosinophilic material that is associated with a patchy chronic inflammatory cell infiltrate and elicits a foreign-body type giant cell reaction. More
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CALCIFYING FIBROUS TUMOR  Left: A localized fibrous nodule lies within the ...
Published: 01 June 2022
CALCIFYING FIBROUS TUMOR Figure 5-15 CALCIFYING FIBROUS TUMOR Left: A localized fibrous nodule lies within the parietal pleura. Right: The tumor is well circumscribed and consists of thick collagen bundles with minimal chronic inflammation and foci of dystrophic calcification within the stroma. More
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SIMPLE AND ATYPICAL MESOTHELIAL HYPERPLASIA  A,B: Simple: A single layer of...
Published: 01 June 2022
SIMPLE AND ATYPICAL MESOTHELIAL HYPERPLASIA Figure 8-8 SIMPLE AND ATYPICAL MESOTHELIAL HYPERPLASIA A,B: Simple: A single layer of mildly atypical mesothelial cells lines chronically inflamed fibrotic pleura (A). An effusion contains an aggregate of histiocytes to the right of a small sheet of ben... More