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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of depressed parenchyma on the liver surface, or even a shrunken liver with a somewhat wrinkled capsule. Microscopically, acute hepatitis is characterized by a variable degree of hepatocyte apoptosis and necrosis, inflammatory cell infiltration, cholestasis, and reactive/regenerative changes. The latter...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of the literature . J Foot Ankle Surg 2015 ; 54 : 747 - 50 . 70. Drivdal M , Slagsvold CE , Aagenaes O , Kase BF . Hereditary lymphedema, characteristics, and variations in 17 adult patients with lymphedema cholestasis syndrome 1/Aagenaes syndrome . Lymphat Res Biol 2014 ; 12...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... clinical presentation. It may be lethal due to the hypocortisolism and has also been associated with neonatal hypoglycemia, convulsions, hypercalcemia ( 171 ), and cholestasis, which are associated with a 20 percent mortality rate if unrecognized ( 172 , 173 ). Single cell type “knock outs” or loss...
Images
Published: 01 January 2022
BLAND LOBULAR CHOLESTASIS Figure 1-28 BLAND LOBULAR CHOLESTASIS The lobules show cholestasis with no inflammation in this example of drug-induced cholestasis. More about this image found in BLAND LOBULAR CHOLESTASIS The lobules show cholestasis with no inflammatio...
Images
Published: 01 January 2022
BILIARY ATRESIA: LOBULAR CHOLESTASIS Figure 6-4 BILIARY ATRESIA: LOBULAR CHOLESTASIS There is mild cholestasis and extramedullary hematopoiesis. More about this image found in BILIARY ATRESIA: LOBULAR CHOLESTASIS There is mild cholestasis and extrame...
Images
Published: 01 January 2022
MODERATE LOBULAR CHOLESTASIS Figure 7-1 MODERATE LOBULAR CHOLESTASIS There is moderate cholestasis, with most of the bile located in the canaliculi. More about this image found in MODERATE LOBULAR CHOLESTASIS There is moderate cholestasis, with most of t...
Images
Published: 01 January 2022
SEVERE LOBULAR CHOLESTASIS Figure 7-2 SEVERE LOBULAR CHOLESTASIS There is severe cholestasis. Bile can be seen in both the hepatocytes and the bile canaliculi. More about this image found in SEVERE LOBULAR CHOLESTASIS There is severe cholestasis. Bile can be seen i...
Images
Published: 01 January 2022
INTRAHEPATIC CHOLESTASIS OF PREGNANCY Figure 13-23 INTRAHEPATIC CHOLESTASIS OF PREGNANCY Prominent canalicular cholestasis without inflammation (bland cholestasis). More about this image found in INTRAHEPATIC CHOLESTASIS OF PREGNANCY Prominent canalicular cholestasis wi...
Images
Published: 01 January 2022
BLAND LOBULAR CHOLESTASIS PATTERN OF INJURY Figure 7-22 BLAND LOBULAR CHOLESTASIS PATTERN OF INJURY There is marked lobular cholestasis, but no inflammation. More about this image found in BLAND LOBULAR CHOLESTASIS PATTERN OF INJURY There is marked lobular choles...
Images
Published: 01 January 2022
BILE CANALICULI Figure 1-9 BILE CANALICULI The bile canaliculi are evident due to cholestasis in this case of biliary obstruction. More about this image found in BILE CANALICULI The bile canaliculi are evident due to cholestasis in this...
Images
Published: 01 January 2022
CHOLESTATIC ACUTE HEPATITIS A Figure 2-1 CHOLESTATIC ACUTE HEPATITIS A The cholestasis and ductular reaction mimic a biliary disease. IgM anti-HAV and exclusion of biliary processes confirmed the diagnosis. Cholestatic features may also be prominent in hepatitis E. More about this image found in CHOLESTATIC ACUTE HEPATITIS A The cholestasis and ductular reaction mimic ...
Images
Published: 01 January 2022
BILIARY ATRESIA: BILE DUCTULAR CHOLESTASIS Figure 6-5 BILIARY ATRESIA: BILE DUCTULAR CHOLESTASIS A bile plug is present in the bile duct lumen. More about this image found in BILIARY ATRESIA: BILE DUCTULAR CHOLESTASIS A bile plug is present in the b...
Images
Published: 01 January 2022
FIC1 DEFICIENCY Figure 6-16 FIC1 DEFICIENCY The lobules show a canalicular pattern of cholestasis. The bile is paler than normal bile. More about this image found in FIC1 DEFICIENCY The lobules show a canalicular pattern of cholestasis. The...
Images
Published: 01 January 2022
CRIGLER-NAJAR SYNDROME TYPE I Figure 6-25 CRIGLER-NAJAR SYNDROME TYPE I The lobules show moderate cholestasis. More about this image found in CRIGLER-NAJAR SYNDROME TYPE I The lobules show moderate cholestasis.
Images
Published: 01 January 2022
BILE DUCTULAR CHOLESTASIS Figure 7-11 BILE DUCTULAR CHOLESTASIS There are bile plugs in the bile ductules. This pattern is also known as cholangitis lenta. More about this image found in BILE DUCTULAR CHOLESTASIS There are bile plugs in the bile ductules. This ...
Images
Published: 01 January 2022
PURE OR BLAND CHOLESTASIS DUE TO ANABOLIC STEROIDS Figure 8-7 PURE OR BLAND CHOLESTASIS DUE TO ANABOLIC STEROIDS Hepatocellular injury, lobular inflammation, bile duct injury, and ductular reaction are minimal or absent. More about this image found in PURE OR BLAND CHOLESTASIS DUE TO ANABOLIC STEROIDS Hepatocellular injury, ...
Images
Published: 01 January 2022
CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION Figure 8-18 CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION This picture can be seen with TPN in both the pediatric and adult patients, while steatosis/steatohepatitis-like changes typically occur in a... More about this image found in CHOLESTASIS AND DUCTULAR REACTION RELATED TO TOTAL PARENTERAL NUTRITION Th...
Images
Published: 01 January 2022
ALCOHOL-RELATED STEATOHEPATITIS Figure 9-33 ALCOHOL-RELATED STEATOHEPATITIS A: The lobules show cholestasis. B: There are numerous ballooned hepatocytes and abundant Mallory hyaline. C: The lobular inflammation is neutrophil rich. More about this image found in ALCOHOL-RELATED STEATOHEPATITIS A: The lobules show cholestasis. B: There...
Images
Published: 01 January 2022
ACUTE FATTY LIVER OF PREGNANCY Figure 13-22 ACUTE FATTY LIVER OF PREGNANCY Canalicular cholestasis and microvesicular steatosis. More about this image found in ACUTE FATTY LIVER OF PREGNANCY Canalicular cholestasis and microvesicular ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-6
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... ages. NEONATAL CHOLESTATIC LIVER DISEASE Neonatal cholestasis is usually defined as presentation with jaundice at birth or within the first few months of life. The most common causes of neonatal cholestasis are biliary atresia (about 30 percent of cases), genetic disorders (25 percent...
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