HIV CENTRAL NERVOUS SYSTEM DISEASE Figure 9-7 HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syndrome (HAD), with ventricular dilatation and sulcal widening. B: HIV encephalitis shows cortical white matter with multinucleated giant cell encephalitis (MGCE). C: HIV enceph... More about this image found in HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syn...

VANISHING BILE DUCT SYNDROME Figure 9-26 VANISHING BILE DUCT SYNDROME The central portal tract has an absent bile ductule that has disappeared in the chronic inflammation. More about this image found in VANISHING BILE DUCT SYNDROME The central portal tract has an absent bile d...

EARLY-ONSET NEONATAL LISTERIOSIS Figure 11-2 EARLY-ONSET NEONATAL LISTERIOSIS Gram stain of lung (A) and central nervous system (B) tissue demonstrates abundant gram-positive bacillary organisms. (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL])... More about this image found in EARLY-ONSET NEONATAL LISTERIOSIS Gram stain of lung (A) and central nervou...

LATE-ONSET NEONATAL LISTERIOSIS Figure 11-3 LATE-ONSET NEONATAL LISTERIOSIS High-power view of a central nervous system inflammatory lesion. (Courtesy of the CDC PHIL) More about this image found in LATE-ONSET NEONATAL LISTERIOSIS High-power view of a central nervous syste...

NOCARDIOSIS Figure 12-23 NOCARDIOSIS A central nervous system (CNS) inflammatory lesion with abscess formation (A,B), scattered beaded gram-positive Nocardia bacilli (C), and numerous single and partly clustered filamentous bacteria with a Grocott methenamine silver (GMS) stain (D). (C: courtesy of the CDC PHIL) More about this image found in NOCARDIOSIS A central nervous system (CNS) inflammatory lesion with absces...

ACTINOMYCOTIC (SULFUR) GRANULE Figure 12-30 ACTINOMYCOTIC (SULFUR) GRANULE A: Central, tangled basophilic filamentous bacteria have a cuff of radiating dense eosinophilic material (Splendore-Hoeppli phenomenon) and surrounding neutrophils/other inflammatory cells. B,C: Gram (B) and fungal sliver... More about this image found in ACTINOMYCOTIC (SULFUR) GRANULE A: Central, tangled basophilic filamentous ...

TUBERCULOUS GRANULOMA Figure 12-51 TUBERCULOUS GRANULOMA Central fibrillogranular (caseous) necrosis with surrounding palisaded epithelioid histiocytes. More about this image found in TUBERCULOUS GRANULOMA Central fibrillogranular (caseous) necrosis with sur...

TUBERCULOUS GRANULOMA Figure 12-54 TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibrillogranular necrosis (A). Some scattered peripheral multinucleated giant cells show a typical Langhans-type morphology (B). More about this image found in TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibr...

RICKETTSIAL POX Figure 14-34 RICKETTSIAL POX There is a central eschar with epidermal and underlying dermal necrosis, as well as dermal perivascular inflammation. (Courtesy of the CDC IDPB) More about this image found in RICKETTSIAL POX There is a central eschar with epidermal and underlying de...

CRYPTOCOCCOSIS OF THE LUNG, CENTRAL NERVOUS SYSTEM, AND SKIN Figure 20-3 CRYPTOCOCCOSIS OF THE LUNG, CENTRAL NERVOUS SYSTEM, AND SKIN Variable inflammatory response ranges from granulomatous (A), lymphocytic (B), to predominantly histiocytic/foam cell (C–E), with associated fungal yeasts (F). More about this image found in CRYPTOCOCCOSIS OF THE LUNG, CENTRAL NERVOUS SYSTEM, AND SKIN Variable infl...

EUMYCETOMA Figure 24-12 EUMYCETOMA Multiple suppurative granulomas contain central granular colonies of fungal hyphae. More about this image found in EUMYCETOMA Multiple suppurative granulomas contain central granular coloni...

TINEA CRURIS Figure 24-32 TINEA CRURIS Central clearing with an active erythematous lesional edge. (Courtesy of Prof. A. Mosam, University of KwaZulu-Natal, Durben, South Africa) More about this image found in TINEA CRURIS Central clearing with an active erythematous lesional edge. (...

KERION Figure 24-37 KERION A central zone of suppurative inflammation in response to an elaborated fragment of infected hair shaft material, showing a peripheral ill-defined granulomatous infiltrate. More about this image found in KERION A central zone of suppurative inflammation in response to an elabor...

CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS Figure 25-3 CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS A: Brain histology shows necrosis and prominent mononuclear inflammation. B: An autopsy case shows prominent necrosis with minimal inflammation. More about this image found in CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS A: Brain histology shows necrosis and...

CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS Figure 25-4 CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS Cerebral tachyzoites and cysts (A) are confirmed as T. gondii on an immunohistochemical stain (B). More about this image found in CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS Cerebral tachyzoites and cysts (A) ar...

AFRICAN TRYPANOSOME TRYPOMASTIGOTES Figure 25-9 AFRICAN TRYPANOSOME TRYPOMASTIGOTES On a blood smear, the central large dark nucleus, small dark basal kinetoplast, long flagellum, and scattered small granules in the organism’s pale cytoplasm are seen. (Giemsa stain; courtesy of the CDC PHIL) More about this image found in AFRICAN TRYPANOSOME TRYPOMASTIGOTES On a blood smear, the central large da...