Search Results for cell

CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION Figure 1-8 CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION A: Neural crest cells directly migrate laterally and ventrally to give rise to cutaneous melanocytes and sympathetic ganglia (SG). B: Slightly later in embryogenesis a different group More about this image found in CURRENT CONCEPT OF NEURAL CREST CELL MIGRATION A: Neural crest cells direc...

FAT CELL METAPLASIA Figure 1-35 FAT CELL METAPLASIA Normal adrenal cortex in an adult shows patchy areas with confluent lipid vacuoles and some individual cells resembling mature adipocytes. This has been referred to as lipomatous metaplasia. More about this image found in FAT CELL METAPLASIA Normal adrenal cortex in an adult shows patchy areas w...

ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION Figure 1-47 ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION At low magnification, cells of the zona glomerulosa (A) contain sparse lipid and have round to oval mitochondria with lamellar cristae. Cells of the zona fasciculata (B) contain many large More about this image found in ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION At low magnification, cell...

ADRENAL HEPATIC UNION WITH ISOLATED CORTICAL CELL NESTS Figure 2-2 ADRENAL HEPATIC UNION WITH ISOLATED CORTICAL CELL NESTS Heterotopic adrenal cortical tissue is within liver parenchyma, with isolated nests of cortical cells. Intrahepatic adrenal heterotopia was present just beneath the liver More about this image found in ADRENAL HEPATIC UNION WITH ISOLATED CORTICAL CELL NESTS Heterotopic adrena...

ONCOCYTIC ADRENAL CORTICAL ADENOMA COEXISTING WITH A CLEAR CELL CORTICAL NODULE Figure 5-13 ONCOCYTIC ADRENAL CORTICAL ADENOMA COEXISTING WITH A CLEAR CELL CORTICAL NODULE The dishomogeneous brown nodule, 2.7 cm in size (bottom), corresponded histologically to an oncocytic adenoma, well More about this image found in ONCOCYTIC ADRENAL CORTICAL ADENOMA COEXISTING WITH A CLEAR CELL CORTICAL NO...

ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Figure 5-22 ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Areas of this adrenal adenoma show an ill-defined spindle cell pattern. More conventional histology was present in other fields. More about this image found in ADRENAL CORTICAL ADENOMA WITH SPINDLE CELL FEATURES Areas of this adrenal ...

ADRENAL CORTICAL CARCINOMA Figure 6-37 ADRENAL CORTICAL CARCINOMA Aspirate smear preparation of an ACC shows cells with compact, eosinophilic cytoplasm (A: hematoxylin and eosin [H&E] stain). Marked variation in nuclear size is visible in tumor cells dispersed or loosely aggregated in small More about this image found in ADRENAL CORTICAL CARCINOMA Aspirate smear preparation of an ACC shows cell...

PHEOCHROMOCYTOMA Figure 8-24 PHEOCHROMOCYTOMA Spindle cell morphology is also seen in tumors with solid cohesive growth. More about this image found in PHEOCHROMOCYTOMA Spindle cell morphology is also seen in tumors with solid...

PHEOCHROMOCYTOMA Figure 8-25 PHEOCHROMOCYTOMA The tumor cell nuclei usually have prominent and occasionally multiple nucleoli, and some have clear pseudo-inclusions. More about this image found in PHEOCHROMOCYTOMA The tumor cell nuclei usually have prominent and occasion...

PHEOCHROMOCYTOMA: CLEAR CELL CHANGE IN VHL DISEASE Figure 8-35 PHEOCHROMOCYTOMA: CLEAR CELL CHANGE IN VHL DISEASE The presence of clear cell change in a pheochromocytoma is associated with VHL disease. More about this image found in PHEOCHROMOCYTOMA: CLEAR CELL CHANGE IN VHL DISEASE The presence of clear c...

PHEOCHROMOCYTOMA: NECROSIS Figure 8-48 PHEOCHROMOCYTOMA: NECROSIS The presence of tumor cell necrosis (A) is a worrisome feature but not significant alone; comedonecrosis (B) is considered to be indicative of more aggressive disease. More about this image found in PHEOCHROMOCYTOMA: NECROSIS The presence of tumor cell necrosis (A) is a wo...

CAROTID BODY PARAGANGLIOMA Figure 9-24 CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition of this paraganglioma raises the possibility of mesenchymal and other spindle cell neoplasms. B: Reticulin stain highlights the spindle cell pattern. More about this image found in CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition...

SMALL BLUE ROUND CELL TUMOR Figure 11-11 SMALL BLUE ROUND CELL TUMOR Immunohistochemically, this tumor was shown to be undifferentiated NB. The cellular tumor is composed of undifferentiated cells with atypical nuclei and scant cytoplasm. No stroma or ganglion cell differentiation is present. More about this image found in SMALL BLUE ROUND CELL TUMOR Immunohistochemically, this tumor was shown to...

DIFFERENTIATING NEUROBLASTOMA Figure 11-14 DIFFERENTIATING NEUROBLASTOMA This tumor shows areas of ganglion cell differentiation, which are still in an immature neuropil matrix, flanked by areas of schwannian stroma (upper right), but also by areas of immature neuroblasts (lower left). When More about this image found in DIFFERENTIATING NEUROBLASTOMA This tumor shows areas of ganglion cell diff...

UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION Figure 11-16 UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION This stage 3 NB in a 5-year-old girl was not pretreated and showed this peculiar undifferentiated spindle cell morphology without presence of neuropil More about this image found in UNDIFFERENTIATED NEUROBLASTOMA WITH SPINDLE CELL DIFFERENTIATION This stag...

UNDIFFERENTIATED NEUROBLASTOMA WITH LARGE CELL HISTOLOGY Figure 11-17 UNDIFFERENTIATED NEUROBLASTOMA WITH LARGE CELL HISTOLOGY This tumor was originally diagnosed as malignant rhabdoid tumor on the basis of morphology and loss of BRG1 immunostaining, until resection showed foci of ganglion cell More about this image found in UNDIFFERENTIATED NEUROBLASTOMA WITH LARGE CELL HISTOLOGY This tumor was or...

MALIGNANT ADRENAL PECOMA Figure 12-16 MALIGNANT ADRENAL PECOMA A: Spindle cell area with cytologic atypia and a mitosis. B: Area of extensive necrosis (top of field). More about this image found in MALIGNANT ADRENAL PECOMA A: Spindle cell area with cytologic atypia and a ...

RENAL CELL CARCINOMA METASTATIC TO ADRENAL GLAND Figure 12-27 RENAL CELL CARCINOMA METASTATIC TO ADRENAL GLAND A: Adrenal metastasis from an ipsilateral renal cell carcinoma. The patient had undergone radical nephrectomy for a large renal cell carcinoma. Metastatic clear cell renal carcinoma More about this image found in RENAL CELL CARCINOMA METASTATIC TO ADRENAL GLAND A: Adrenal metastasis fro...

ADRENAL INVOLVEMENT BY LYMPHOMA Figure 12-28 ADRENAL INVOLVEMENT BY LYMPHOMA A: The tumor, a large B-cell lymphoma, replaces much of the adrenal gland, with only a few small nests of pale-staining cortical cells present in this field. B: Immunostain for CD20 is diffusely positive. More about this image found in ADRENAL INVOLVEMENT BY LYMPHOMA A: The tumor, a large B-cell lymphoma, rep...

INTRACORTICAL LEYDIG CELLS Figure 1-38 INTRACORTICAL LEYDIG CELLS A solitary cluster of Leydig (or hilus) cells with numerous Reinke crystalloids were noted incidentally in the normal part of an adrenal gland removed because of an aldosterone-secreting cortical adenoma. Most of the Leydig cells More about this image found in INTRACORTICAL LEYDIG CELLS A solitary cluster of Leydig (or hilus) cells w...