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SOLID SEROUS ADENOMA  In this <span class="search-highlight">case</span>, most of the neoplasm is solid, although...
Published: 01 March 2023
SOLID SEROUS ADENOMA Figure 4-10 SOLID SEROUS ADENOMA In this case, most of the neoplasm is solid, although some micro cystic regions are present (bottom). More
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HEPATOID CARCINOMA  This <span class="search-highlight">case</span> is composed of polygonal cells with abundant ...
Published: 01 March 2023
HEPATOID CARCINOMA Figure 8-13 HEPATOID CARCINOMA This case is composed of polygonal cells with abundant eosinophilic cytoplasm. Luminal bile is present. More
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ACINAR CELL CARCINOMA  A <span class="search-highlight">case</span> with oncocytic cytoplasm.
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-16 ACINAR CELL CARCINOMA A case with oncocytic cytoplasm. More
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MIXED ACINAR-NEUROENDOCRINE CARCINOMA  This <span class="search-highlight">case</span> has separate, morphologica...
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-39 MIXED ACINAR-NEUROENDOCRINE CARCINOMA This case has separate, morphologically recognizable com ponents, with the acinar elements comprising the central portion (top, and upper inset) and the neuroendocrine elements lining the periphery, beneath th... More
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MIXED ACINAR-NEUROENDOCRINE CARCINOMA  In this <span class="search-highlight">case</span> the two cell population...
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-42 MIXED ACINAR-NEUROENDOCRINE CARCINOMA In this case the two cell populations are not distinct, and the morphology varies gradually from acinar, with eosinophilic cytoplasm (center), to regions with neuro-endocrine morphology (upper right). More
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MULTIPLE INSULINOMAS  A <span class="search-highlight">case</span> of hereditary insulinomatosis, immunolabeled f...
Published: 01 March 2023
MULTIPLE INSULINOMAS Figure 12-69 MULTIPLE INSULINOMAS A case of hereditary insulinomatosis, immunolabeled for insulin, showing multiple, almost confluent, insulinomas. More
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MUCINOUS CYSTIC NEOPLASM  In some <span class="search-highlight">cases</span>, the stroma is extensively luteiniz...
Published: 01 March 2023
MUCINOUS CYSTIC NEOPLASM Figure 5-15 MUCINOUS CYSTIC NEOPLASM In some cases, the stroma is extensively luteinized, including in regions extending into the adjacent parenchyma. More
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BRANCH DUCT-TYPE INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM  Some <span class="search-highlight">cases</span> show m...
Published: 01 March 2023
BRANCH DUCT-TYPE INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM Figure 6-7 BRANCH DUCT-TYPE INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM Some cases show multicentricity, with multiple cystic branch ducts separated by uninvolved parenchyma. More
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ACINAR CELL CARCINOMA  A: Most <span class="search-highlight">cases</span> are hypercellular at low power, with m...
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-6 ACINAR CELL CARCINOMA A: Most cases are hypercellular at low power, with minimal fibrous stroma. B: Sometimes, fibrous bands separate the neoplasm into hyper-cellular islands. C: Only rarely are the individual neoplastic glands surrounded by stroma. More
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PANCREATIC NEUROENDOCRINE TUMOR  Some <span class="search-highlight">cases</span> have cytoplasmic vacuolization ...
Published: 01 March 2023
PANCREATIC NEUROENDOCRINE TUMOR Figure 12-44 PANCREATIC NEUROENDOCRINE TUMOR Some cases have cytoplasmic vacuolization (left). Rarely a pseudopapillary pattern is present (right). More
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MALIGNANT MESOTHELIOMA  Left: Localized <span class="search-highlight">cases</span> can present within the pancre...
Published: 01 March 2023
MALIGNANT MESOTHELIOMA Figure 13-44 MALIGNANT MESOTHELIOMA Left: Localized cases can present within the pancreas; note the adjacent pancreatic tissue (lower right). Right: The neoplasm has a microcystic and papillary pattern. More
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PANCREATOBLASTOMA  Left: The stroma is often hypercellular, especially in p...
Published: 01 March 2023
PANCREATOBLASTOMA Figure 10-6 PANCREATOBLASTOMA Left: The stroma is often hypercellular, especially in pediatric cases. Right: Sometimes the degree of cellularity suggests that the stroma is also neoplastic; heterologous bone is present in this case. More
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ACINAR CELL CARCINOMA  Staining with periodic acid–Schiff (PAS) with diasta...
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-21 ACINAR CELL CARCINOMA Staining with periodic acid–Schiff (PAS) with diastase digestion reveals intense, granular positivity in cases with numerous zymogen granules (left), but other cases show only faint staining (right). More
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SOLID PSEUDOPAPILLARY NEOPLASM  A: Grossly, there is a predominantly solid,...
Published: 01 March 2023
SOLID PSEUDOPAPILLARY NEOPLASM Figure 11-2 SOLID PSEUDOPAPILLARY NEOPLASM A: Grossly, there is a predominantly solid, circumscribed, soft tumor with hemorrhage and cysts. B: This small example has no cystic change. C: Larger case with friable tan tumor tissue and ragged degenerative cysts. D: ... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI: 10.55418/9781933477275-09
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... with predominantly acinar differentiation are uncommon. A clinical paraneoplastic syndrome due to massive lipase secretion in some cases of acinar cell carcinoma ( 5 – 7 ) helped draw attention to acinar cell carcinomas before their distinctive histologic features were recognized, and more recent genomic studies...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI: 10.55418/9781933477275-13
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... the neoplastic cells form lymphatic channels. The first case was reported in 1913, and since then over 80 cases have been reported ( 1 , 2 ). These neoplasms occur most commonly adjacent to the pancreas or are connected to the organ by a pedicle, rather than within it, but intrapancreatic cases also occur. Less...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI: 10.55418/9781933477275-10
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... et al. ( 4a ) in their 1977 report of two cases. A review of earlier literature, however, reveals that a pancreatic carcinoma in an infant reported by Becker ( 4b ) in 1957 was almost certainly a pancreatoblastoma, and Frable et al. ( 4c ) reported the pathologic features of a case in 1971 under...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI: 10.55418/9781933477275-11
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... designation as Frantz tumor. Subsequent case reports characterized the histologic features and the typical presentation in young female patients. A report of a “papillary epithelial neoplasm” in a child by Hamoudi et al. in 1970 ( 5 ) led to its other eponym, Hamoudi tumor. Documentation of metastatic disease...
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PANCREATIC NEUROENDOCRINE CARCINOMA, LARGE CELL TYPE  Immunolabeling for ch...
Published: 01 March 2023
PANCREATIC NEUROENDOCRINE CARCINOMA, LARGE CELL TYPE Figure 12-82 PANCREATIC NEUROENDOCRINE CARCINOMA, LARGE CELL TYPE Immunolabeling for chromogranin A is extensive in this case. More
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MIXED ACINAR-DUCTAL CARCINOMA  There is expression of both trypsin (left) a...
Published: 01 March 2023
MIXED ACINAR-DUCTAL CARCINOMA Figure 9-50 MIXED ACINAR-DUCTAL CARCINOMA There is expression of both trypsin (left) and carcinoembryonic antigen (right) in the case seen in figure 9-49 . More