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ADRENAL CORTICAL CARCINOMA Figure 6-15 ADRENAL CORTICAL CARCINOMA Most tumor cells in this case have large, coarse cytoplasmic vacuoles, which distend many cells and displace the nucleus to the periphery. Some cells have a “signet ring” appearance. More about this image found in ADRENAL CORTICAL CARCINOMA Most tumor cells in this case have large, coars...

ADRENAL CORTICAL CARCINOMA Figure 6-14 ADRENAL CORTICAL CARCINOMA In most cases, a population of eosinophilic lipid-poor cells predominates (A), with irregular nuclei and prominent nucleoli (B). More about this image found in ADRENAL CORTICAL CARCINOMA In most cases, a population of eosinophilic lip...

is present in bottom third of field, adrenal medulla is in middle third, and adrenal cortex is at top of field with zona reticularis abutting on medulla. B: Adrenal metastasis of clear cell renal carcinoma in a different case has a nesting pattern with rich microvasculature. Optically clear cytoplasm More about this image found in RENAL CELL CARCINOMA METASTATIC TO ADRENAL GLAND A: Adrenal metastasis fro...

PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES Figure 8-31 PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structures may be found in a few scattered cells or, rarely, as in this case, may be numerous. More about this image found in PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structur...

VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING Figure 8-45 VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING CAIX positivity is associated with VHL-related disease; it may be diffuse or focal as in this case. More about this image found in VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING CAIX positivity is associat...

NECROSIS IN ADRENAL CORTICAL CARCINOMA Figure 6-12 NECROSIS IN ADRENAL CORTICAL CARCINOMA Necrotic areas may be focal punctate (A) or extensive (B), in some cases involving most of the tumor (C). More about this image found in NECROSIS IN ADRENAL CORTICAL CARCINOMA Necrotic areas may be focal punctat...

PEDIATRIC ADRENAL CORTICAL CARCINOMA Figure 6-44 PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a malignant pediatric adrenal cortical tumor. (Same case as fig. 6-42 .) More about this image found in PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a m...

NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-28 NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated with fibrin (A) and showing mild atypia (B) are present in hemorrhagic areas (same case as fig. 5-27 ). More about this image found in NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated ...

CAROTID BODY PARAGANGLIOMA Figure 9-20 CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsule and tumor blood vessels. The presence of hemosiderin suggests repeated ischemia and infarction as possible factors contributing to the development of sclerosis in this case. More about this image found in CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsul...

CAROTID BODY PARAGANGLIOMA Figure 9-30 CAROTID BODY PARAGANGLIOMA Preoperative embolization of this tumor was performed with gel beads, which are seen occluding cavernous blood vessels. There is no postembolic necrosis in this case, probably reflecting a shorter interval between embolization More about this image found in CAROTID BODY PARAGANGLIOMA Preoperative embolization of this tumor was per...

ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Figure 5-26 ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myelolipomatous changes are present in association with an adenomatous component made of lipid-rich clear cells (same case as fig. 5-16 ). More about this image found in ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myel...

PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-43 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1 (A). Ki-67 index (B) was 5 percent, whereas p53 was expressed in rare nuclei (C). (Same case as figs. 6-40 and 6-41 .) More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1...

PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-41 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progressively higher magnification. It lacks necrosis and signs of invasion and showed low mitotic and proliferation indexes. Final Wieneke score was 0. (Same case as fig. 6 More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progre...

this case is composed of only cortical cells, without a medullary component. More about this image found in ACCESSORY ADRENAL CORTICAL TISSUE A: Longitudinal section of a newborn tes...

obscure the vital tumor component in some instances. In this case, vital neuroblasts are easily seen. More about this image found in NEUROBLASTOMA WITH EXTENSIVE DYSTROPHIC CALCIFICATION NBs may show varying...