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Figure 6-15
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-15 ADRENAL CORTICAL CARCINOMA Most tumor cells in this case have large, coarse cytoplasmic vacuoles, which distend many cells and displace the nucleus to the periphery. Some cells have a “signet ring” appearance. More about this image found in ADRENAL CORTICAL CARCINOMA Most tumor cells in this case have large, coars...
Images
Figure 6-14
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA Figure 6-14 ADRENAL CORTICAL CARCINOMA In most cases, a population of eosinophilic lipid-poor cells predominates (A), with irregular nuclei and prominent nucleoli (B). More about this image found in ADRENAL CORTICAL CARCINOMA In most cases, a population of eosinophilic lip...
Book
Book cover for Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
Images
Figure 12-27
Published: 01 December 2024
is present in bottom third of field, adrenal medulla is in middle third, and adrenal cortex is at top of field with zona reticularis abutting on medulla. B: Adrenal metastasis of clear cell renal carcinoma in a different case has a nesting pattern with rich microvasculature. Optically clear cytoplasm More about this image found in RENAL CELL CARCINOMA METASTATIC TO ADRENAL GLAND A: Adrenal metastasis fro...
Book Chapter
Book cover for Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., or metastases to the adrenal gland from distant sites. There are also a few case reports of both endocrine and nonendocrine tumors potentially related to the adrenal gland developmentally, either by steroidogenic lineage or by proximity to the adrenogenital/gonadal ridge (see chapter 1 ). Non-neoplastic causes...
Book Chapter
Book cover for Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... adrenal-hepatic adhesion and union on that side. Adrenal fusion is a rare anomaly in which the adrenal glands are united in the midline ( fig. 2-3 ), with some medial deviation of the kidneys in most cases. The fused adrenal glands may have a horseshoe or butterfly appearance. This abnormality...
Book Chapter
Book cover for Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... HEREDITARY SYNDROMES ASSOCIATED WITH ADRENAL CORTICAL PROLIFERATIONS Syndrome Gene(s) Adrenal Cortical Phenotype Relative Risk of Adrenal Cortical Cancer Main Other Associated Features Beckwith-Wiedemann syndrome a IGF2 locus Cysts, adenoma (carcinoma in case reports...
Images
Figure 8-31
Published: 01 December 2024
PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES Figure 8-31 PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structures may be found in a few scattered cells or, rarely, as in this case, may be numerous. More about this image found in PHEOCHROMOCYTOMA: INTRACYTOPLASMIC HYALINE GLOBULES These hyaline structur...
Images
Figure 8-45
Published: 01 December 2024
VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING Figure 8-45 VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING CAIX positivity is associated with VHL-related disease; it may be diffuse or focal as in this case. More about this image found in VHL-ASSOCIATED PHEOCHROMOCYTOMA: CAIX STAINING CAIX positivity is associat...
Images
Figure 6-12
Published: 01 December 2024
NECROSIS IN ADRENAL CORTICAL CARCINOMA Figure 6-12 NECROSIS IN ADRENAL CORTICAL CARCINOMA Necrotic areas may be focal punctate (A) or extensive (B), in some cases involving most of the tumor (C). More about this image found in NECROSIS IN ADRENAL CORTICAL CARCINOMA Necrotic areas may be focal punctat...
Images
Figure 6-44
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL CARCINOMA Figure 6-44 PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a malignant pediatric adrenal cortical tumor. (Same case as fig. 6-42 .) More about this image found in PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a m...
Images
Figure 5-28
Published: 01 December 2024
NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-28 NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated with fibrin (A) and showing mild atypia (B) are present in hemorrhagic areas (same case as fig. 5-27 ). More about this image found in NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated ...
Book Chapter
Book cover for Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...” disease designation in the European Union and in the United States (less than 50 cases per 100,000 population and less than 64 cases per 10,000 population, respectively) ( 1 ). The annual incidence ranges between 0.7 to 2.0 cases per million in the United States ( 2 ), with no significant changes over...
Images
Figure 9-20
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-20 CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsule and tumor blood vessels. The presence of hemosiderin suggests repeated ischemia and infarction as possible factors contributing to the development of sclerosis in this case. More about this image found in CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsul...
Images
Figure 9-30
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-30 CAROTID BODY PARAGANGLIOMA Preoperative embolization of this tumor was performed with gel beads, which are seen occluding cavernous blood vessels. There is no postembolic necrosis in this case, probably reflecting a shorter interval between embolization More about this image found in CAROTID BODY PARAGANGLIOMA Preoperative embolization of this tumor was per...
Images
Figure 5-26
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Figure 5-26 ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myelolipomatous changes are present in association with an adenomatous component made of lipid-rich clear cells (same case as fig. 5-16 ). More about this image found in ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myel...
Images
Figure 6-43
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-43 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1 (A). Ki-67 index (B) was 5 percent, whereas p53 was expressed in rare nuclei (C). (Same case as figs. 6-40 and 6-41 .) More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1...
Images
Figure 6-41
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-41 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progressively higher magnification. It lacks necrosis and signs of invasion and showed low mitotic and proliferation indexes. Final Wieneke score was 0. (Same case as fig. 6 More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progre...
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Images