Search Results for cardiac

... exhibits small intracytoplasmic vacuoles with flocculent content, which are a well-known characteristic of SDH-deficient renal cell carcinoma but extremely rare in SDH-deficient paraganglioma. PIGMENTED CARDIAC PARAGANGLIOMA Figure 9-27 PIGMENTED CARDIAC PARAGANGLIOMA A: Dark brown to black granules...

... disease PDE11A, PDE8B, PRKACA Isolated micronodular adrenal disease <1% — Carney complex and isolated familial PPNAD PRKAR1A (PDE11A, PDE8B rare) PPNAD (carcinoma in case reports) <1% Pituitary and thyroid tumors, cardiac myxomas, peripheral nerve sheath tumors...

... associated with major central nervous system (CNS) malformations, renal agenesis, and complex cardiac anomalies ( 4 ). Renal agenesis is sometimes associated with an adrenal gland of abnormal shape, which may be oval with a smooth contour. FUSION OF ADRENAL GLANDS Figure 2-3 FUSION OF ADRENAL...

... hypertension, headache, fatigue, and weakness. In contrast, when present, hypokalemia can be insidious without obvious cause. More florid forms may present with cardiac dysrhythmias, polydipsia, polyuria, cramping, headaches, and weakness ( 17 ). Laboratory findings include increased plasma aldosterone levels...

... cell tumors, or mucocutaneous pigmentation [ fig. 4-22 ]), investigation for possible cardiac myxoma, frequently multiple, is recommended to permit early detection and treatment. Additional but more rare manifestations in Carney complex include cardiomyopathy, colonic polyps and adenocarcinoma...

... SDH-DEFICIENT PARAGANGLIOMA A: This cardiac paraganglioma from a patient with a pathogenic SDHB variant has round nesting architecture, oncocytic cytology with abundant eosinophilic cytoplasm, and focal tendency to form pseudorosettes. B: SDHB immunohistochemistry is negative, with retained...

... as hibernoma, may be coincidental. Cardiomyopathy may occur in patients with prolonged catecholamine excess, causing arrhythmia and cardiac failure. Weight loss, ileus, abdominal distention, pain, and other features of increased adrenergic tone should all be considered as manifestations of pheochromocytoma...

... histology is illustrated in figure 12-9 . The child also had the Kasabach-Merritt syndrome with thrombocytopenic purpura and died of high output cardiac failure. Approximately 40 examples of primary adrenal angiosarcoma have been reported in English publications ( 29 ), one coexisting...

.... Martucci   VL , Emaminia   A , del Rivero   J , et al . Succinate dehydrogenase gene mutations in cardiac paragangliomas . Am J Cardiol   2015 ; 115 : 1753 - 9 . 29. Kameneva   P , Artemov   AV , Kastriti   ME , et al . Single-cell transcriptomics of human embryos identifies...

... ). Electrocardiogram (ECG) findings include ST-segment elevations that can resemble myocardial infarction, but cardiac catheterization is typically normal. Presentation with a bundle branch block or the presence of Q waves is associated with a worse outcome, including death. Echocardiography can define the ventricular...

...Table 16-2 CLINICAL AND ANCILLARY TEST FINDINGS IN INFECTIVE ENDOCARDITIS Clinical Features Test Results Fever >38°C Cardiac murmur Splenomegaly Petechia, splinter hemorrhages Osler nodes or Roth spots Metastatic infections (e.g., vertebral osteomyelitis) Arterial emboli (e.g...

... , Fuenmayor   C , Inglessis   I . Cardiac involvement is a constant finding in acute Chagas’ disease: a clinical, parasitological and histopathological study . Int J Cardiol   1997 ; 60 : 49 - 54 . 9. Otani   MM , Vinelli   E , Kirchhoff   LV , et al . WHO comparative evaluation...

... and, less frequently, cardiac muscle. Sarcocystis spp cysts are also found in smooth muscle of various organs, including the esophagus and larynx. Since most cases are asymptomatic, Sarcocystis spp are often found incidentally in skeletal muscle surrounding a cancer resection...

... 9 Respiratory 33 13 3 by PCR, 10 by serology 4 9 Cardiac 22 3 1 by PCR, 2 by serology 1 2 Multisystem 15 3 2 by PCR, 1 by serology 2 1 Hepatic 8 0 0 0 Other 7 0 0 0 All cases 122 34 13 21 a Serology includes enzyme immune assay or indirect...

... circinate rash. There may also be malaise, weakness, anorexia, and weight loss, associated with anemia, leukocytosis, and a strikingly raised erythrocyte sedimentation rate (ESR). Hypergammaglobulinemia (especially IgM) due to polyclonal B-cell activation is characteristic. Cardiac involvement is frequent...