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Images
Published: 01 September 2024
HSIL AND CARCINOMA Figure 9-37 HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, with high nuclear to cytoplasmic ratio, coarse chromatin, and nuclear irregularity (SurePath cytology, Papanicolaou stain). B: HSIL with acanthosis, hyperkeratosis (at left), parakeratosis (a... More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...
Images
Published: 01 September 2024
HSIL AND CARCINOMA Figure 9-37 HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, with high nuclear to cytoplasmic ratio, coarse chromatin, and nuclear irregularity (SurePath cytology, Papanicolaou stain). B: HSIL with acanthosis, hyperkeratosis (at left), parakeratosis (a... More about this image found in HSIL AND CARCINOMA A: Cohesive and singly scattered hyperchromatic cells, ...
Images
Published: 01 September 2024
COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA Figure 9-35 COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA A: LSIL. B: HSIL. C: Squamous cell carcinoma. (Courtesy of Dr. L.... More about this image found in COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL L...
Images
Published: 01 September 2024
HEPATOCELLULAR CARCINOMA (HCC) ARISING AGAINST A BACKGROUND OF CHRONIC HCV INFECTION Figure 5-9 HEPATOCELLULAR CARCINOMA (HCC) ARISING AGAINST A BACKGROUND OF CHRONIC HCV INFECTION A: Gross view of cirrhotic liver with portal hypertension and circumscribed tumor at left. B,C: Neoplastic hepatocy... More about this image found in HEPATOCELLULAR CARCINOMA (HCC) ARISING AGAINST A BACKGROUND OF CHRONIC HCV ...
Images
Published: 01 September 2024
EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Figure 8-11 EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associated lymphocyte infiltrate (B), with pancytokeratin immunohistochemistry (C) confirm the epithelial nature of the neoplasm. More about this image found in EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associ...
Images
Published: 01 September 2024
NASOPHARYNGEAL CARCINOMA Figure 8-12 NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encoded small RNA (EBER) in situ hybridization (ISH), confirming the EBV association of the tumor. More about this image found in NASOPHARYNGEAL CARCINOMA Strong epithelial positivity is seen on EBV-encod...
Images
Published: 01 September 2024
MERKEL CELL CARCINOMA Figure 9-50 MERKEL CELL CARCINOMA A: At low power, the small round blue cell tumor is centered on the dermis. B: Higher power shows sheets of cells with a high nuclear to cytoplasmic ratio, prominent apoptosis, and brisk mitotic activity. C: Classic paranuclear “dot-like” ... More about this image found in MERKEL CELL CARCINOMA A: At low power, the small round blue cell tumor is ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., gut Invasive cervical carcinoma b Cervix, HPV-associated Anal carcinoma Anus, HPV-associated Other non-AIDS defining cancers (NADC) Lung adenocarcinoma; hepatocellular carcinoma (associated with HBV and HCV coinfections) Other Direct HIV-Induced Lesions HIV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., plasmoblastic lymphoma, and nasopharyngeal carcinoma I EBNA1, with EBERs Responsible for maintenance and reproduction of the episomal EBV genome Burkitt lymphoma, plasmoblastic lymphoma, and primary effusion lymphoma 0 EBNA1 and LMP2A Resting B cells in germinal centers Not associated with neoplasia...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Hepatocellular carcinoma Antivirals (tenofivir, entecavir and pegylated interferon) Hepatitis C (HCV) Flaviviridae Positive-strand RNA 55 nm in diameter 6 major and 1 minor genotype Parenteral via blood and bodily fluids (especially IV drug use) Perinatal and sexual transmission much less common than HBV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Tuberculosis Syphilis Yaws Fungal infections (e.g., tinea, blastomycosis) Leishmaniasis Granuloma annulare Sarcoidosis Morphea Sweet syndrome Pyoderma gangrenosum Lupus erythematosus Neoplastic/paraneoplastic Lymphoma Basal cell carcinoma Systemic amyloidosis Pathologic Findings The histopathologic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., including verruca vulgaris, condyloma acuminatum, chickenpox, and bacterial folliculitis Skin tumors, including syringoma, basal cell carcinoma, and steatocystoma Other skin infections, including acne vulgaris, milia, sebaceous hyperplasia, and papular urticaria Pathologic Findings Virtually all human...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... transformation to squamous cell carcinoma is a rare complication. The clinical differential diagnosis includes a spectrum of other sexually transmitted diseases, as well as other infections that present with mucosal or cutaneous ulcers (such as tuberculosis, paracoccidioidomycosis, and others). Pathologic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... carcinoma ( 98 ). Frequently, the term BCGosis is used for disseminated disease, while BCGitis is used to describe localized BCG disease. Stains that highlight mycobacteria include acid-fast stains that use a harsh decolorizing acid (such as a Ziehl-Neelsen stain), Gram stain, and silver...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... percent of gastric peptic ulcers are associated with H. pylori infection. The consequences of colonization by the organism (associated gastritis, duodenal and gastric ulceration) as well as long-term complications such as gastric carcinoma and lymphoma, may result in a wide range of upper GIT...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., mycobacterial infections, and squamous cell carcinoma. The fungal organisms are usually easily visualized as hyaline structures on routine H&E-stained sections, but can be highlighted with fungal silver (e.g., Grocott) stains and PAS. The latter stains endospores but not spherules. The spherules range...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Invasive breast carcinoma is a broad category of epithelial malignancies, most with overlapping clinical and imaging characteristics, as well as macroscopic features, but each with varied microscopic features. It is these latter characteristics that are used to classify breast carcinomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the potential for diagnostic confusion with skin adnexal (sebaceous or sweat gland) neoplasms, metastatic renal cell carcinoma, or xanthomatous histiocytic proliferations. DEEP PENETRATING NEVUS-LIKE (PLEXIFORM) MELANOMA Some melanomas may be confused with, or arise in association with, a deep penetrating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-22
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and only clinical manifestation of metastatic melanoma of unknown primary. A metastasis may present as a pigmented or amelanotic papule or nodule. It may be confused with a nevus, primary melanoma, or nonmelanocytic lesion (e.g., carcinoma, angioma, lipoma, cyst) ( 1 – 3 ). When the metastatic deposit...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... syndrome, with risk for ocular melanoma, mesothelioma, renal cell carcinoma, and other neoplasms ( Table 10-2 ) ( 11 ). Microscopic features suggestive of a germline mutation include the presence of junctional nests with BAP1 loss and fatty metaplasia of dermal melanocytes. Some BAP1-inactivated nevi show...
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