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Figure 7-38

METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES A: Metastatic breast ...

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in Neck > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES Figure 7-38 METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES A: Metastatic breast adenocarcinoma was immunohistochemically positive for GATA3 and TRPS1, with crowded atypical glandular cells. B: Metastatic gastric adenocarcinoma More about this image found in METASTATIC CARCINOMAS TO SUPRACLAVICULAR LYMPH NODES A: Metastatic breast ...
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Figure 8-130

METASTATIC TUMORS A: Nests and glands with central necrosis are noted in t...

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in Ear and Temporal Bone > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
METASTATIC TUMORS Figure 8-130 METASTATIC TUMORS A: Nests and glands with central necrosis are noted in this metastatic adenocarcinoma determined to be from the breast. B: A well-developed glandular neoplasm is noted adjacent to fragments of bone in this metastatic breast carcinoma. (Courtesy More about this image found in METASTATIC TUMORS A: Nests and glands with central necrosis are noted in t...
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Figure 131

METASTATIC TUMORS In selected cases, confirmation with various immunohisto...

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in Ear and Temporal Bone > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
METASTATIC TUMORS Figure 131 METASTATIC TUMORS In selected cases, confirmation with various immunohistochemistry studies may help establish the diagnosis. This breast carcinoma showed strong nuclear reactivity with estrogen receptor (A), and with GATA3 (nuclear) (B), helping to confirm More about this image found in METASTATIC TUMORS In selected cases, confirmation with various immunohisto...
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Figure 1-139

OLFACTORY NEUROBLASTOMA A: Calcification and tumor necrosis (black arrow) ...

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in Sinonasal Cavity > Tumors of the Upper Aerodigestive Tract, Ear, and Jaw
Published: 01 June 2025
OLFACTORY NEUROBLASTOMA Figure 1-139 OLFACTORY NEUROBLASTOMA A: Calcification and tumor necrosis (black arrow) are seen in intermediate- and high-grade tumors. B: There is focal gangliocytic (black arrow) differentiation. C: Metastatic breast carcinoma is identified (white arrows) within More about this image found in OLFACTORY NEUROBLASTOMA A: Calcification and tumor necrosis (black arrow) ...
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Oropharynx

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
..., and mesenchymal components. While PA is the most common salivary gland tumor overall and occurs at myriad minor salivary gland locations, even nonsalivary sites such as the lung, skin, and breast, it is rare in the oropharynx. The most common site is the soft palate, followed by the base of tongue ( 92...
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Neck

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... Posterior triangle group (levels VA, VB) Nasopharynx, oropharynx, thyroid, skin and soft tissue of the posterior scalp and neck Supraclavicular group (level VB) Thyroid and non-head and neck sites: lung, gastrointestinal tract, genitourinary tract, breast Anterior compartment group (level VI...
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Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... to be older (mean, 56 years), with both sexes affected approximately equally, taking into consideration the characteristics of the underlying tumor (breast and uterine carcinomas in females; prostate adenocarcinoma in males), with others showing an equal distribution ( 1351 – 1368 ). Clinical Features. While...
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Oral Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... arise in many subcutaneous and soft tissue sites including the lung, breast, and gastrointestinal tract, but more than 50 percent of cases involve the head and neck ( 112 , 123 , 124 ). Of head and neck cases, the oral cavity accounts for about 70 percent, with the tongue being the most common location...
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Hypopharynx, Larynx, and Trachea

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... of metastases to the head and neck by primary site and type, the majority of metastases are melanomas or carcinomas, and among the carcinomas, gastrointestinal, lung, breast, and prostate tumors are the most common. Metastatic lung adenocarcinoma, in particular, may mimic a neuroendocrine tumor if the latter...
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Sinonasal Cavity

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
...: Metastatic breast carcinoma is identified (white arrows) within an ONB (tumor-to-tumor metastasis). D: ONB within a cervical lymph node. Additional histologic features are rarely encountered, and include ganglion cells ( fig. 1-139B ), and ganglioneuroma or ganglioneuroblastoma features ( 769 , 837 – 839...
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Jaw

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
... lesions are ruled out. Metastases to the gnathic bones occurs in older individuals, usually in the fourth and seventh decades, and most frequently are lung, gastrointestinal, renal, and breast primaries with a different histology than RMS-TFCP2 ( 781 ). Metastatic sarcoma to the gnathic bones is extremely...
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Figure 12-24

ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND A: The pattern of gro...

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in Other Adrenal Neoplasms and Tumor-Like Lesions > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND Figure 12-24 ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND A: The pattern of growth shows a well-developed glandular arrangement of tumor cells. B: Metastatic poorly differentiated adenocarcinoma has a sinusoidal pattern, with growth More about this image found in ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND A: The pattern of gro...
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Figure 4-22

COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pi...

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in Adrenal Cortical Nodular Diseases > Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION Figure 4-22 COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pigmented lesions about the mouth. The patient also had a darkly pigmented lesion on the vulva, probably a blue nevus. B: Cutaneous myxoma on the breast of the same More about this image found in COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pi...
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Hereditary Predisposition to Adrenal Cortical Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... syndrome FLCN Oncocytic adenoma (in case reports) <1% Skin hamartomas, pulmonary cysts, oncocytoid renal neoplasms (oncocytoma and renal cell carcinoma) Li-Fraumeni syndrome TP53 Carcinoma 3-5% (adults) 50-80% (children) Gliomas, breast and lung carcinomas, sarcomas...
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Other Adrenal Neoplasms and Tumor-Like Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). The leading sources of adrenal metastases were breast (53.9 percent), lung (35.6 percent), kidney (24 percent), stomach (21 percent), pancreas (19 percent), ovary (17 percent), and colon (14.4 percent). Endometrial carcinomas rarely give rise to adrenal metastases ( 94 ). In a more recent study of 464...
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Book Chapter

Adrenal Cortical Nodular Diseases

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... distribution (lentigines) Myxomas Heart Myxomas Adrenal gland PPNAD with Cushing syndrome Pituitary gland Pituitary GH-secreting neuroendocrine tumor with acromegaly Breast Myxomatosis Ductal adenoma Testis Large cell calcifying Sertoli cell tumor Thyroid gland Follicular nodular...
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Physiology, Development, and Anatomy of the Adrenal Glands

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in living patients ( 39 ). In a study of adrenal glands obtained surgically from adult females undergoing staged bilateral adrenalectomy for advanced breast cancer, the average weight of individual glands was 4.0 g (1 SD = 0.8 g). Adrenal glands obtained at autopsy were heavier (average, 6.0 g), probably...
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Book Chapter

Adrenal Cortical Carcinoma

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of patients had a history of other malignancies and 3 percent developed other malignancies after ACC diagnosis ( 8 ). Associated malignancies were extremely variable, including different types of carcinomas (prostate, bladder, lung, thyroid gland, breast, endometrial, cervical, renal, cutaneous non...
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Introduction and Methods

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... on fresh tissue ( 11 , 12 ). Illustrative Case: A 68-year-old woman presents with altered mental status. She has a history of breast cancer, treated with lumpectomy and radiation 10 years previously. One week before admission to the hospital, she developed a headache and symptoms of sinusitis. Physical...
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Systemic Infections

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inside the host, the bacteria begin to replicate in lymphoid organs, the reproductive tract, and the mammary glands. Human-to-human transmission is rare but has been documented, including transmission across the placenta, to infants through breast milk, and via the sexual route ( 4 ). Individuals...
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