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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Invasive breast carcinoma is a broad category of epithelial malignancies, most with overlapping clinical and imaging characteristics, as well as macroscopic features, but each with varied microscopic features. It is these latter characteristics that are used to classify breast carcinomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...The prepubertal breast is composed of stroma and lactiferous ducts; little branching of the ducts is seen, and lobuloalveolar differentiation is rudimentary. With the onset of puberty in girls, the ducts elongate, branch, and begin to develop lobuloacinar units under the combined influence...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Lesions occurring in the female breast may also occur in the male breast, albeit with far lesser frequency. Myofibroblastoma is one lesion that had historically been reported to be more frequent in males, but is now recognized to occur with equal frequency in men and women. Other entities...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...As with any field in pathology, appropriate specimen processing is critical to tissue evaluation. Breast tissue, in particular, due to its inherently fatty composition requires special attention to adequate fixation prior to processing in order to ensure optimal microscopic examination and accuracy...
Images
<span class="search-highlight">BREAST</span> NEVUS  A: The compound melanocytic nevus shows nests of varying size...
Published: 01 February 2024
BREAST NEVUS Figure 5-7 BREAST NEVUS A: The compound melanocytic nevus shows nests of varying size and shape with a junctional shoulder. B: Large nests of melanocytes are seen with cell dyscohesion (arrow). More about this image found in BREAST NEVUS A: The compound melanocytic nevus shows nests of varying size...
Images
PLAQUE-TYPE BLUE NEVUS INVOLVING <span class="search-highlight">BREAST</span> TISSUE  A: Diffuse involvement of t...
Published: 01 February 2024
PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE Figure 8-23 PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of the stroma of the breast by pigmented melanocytes. B: The melanocytes display spindle, epithelioid, and dendritic features and are cytologically bland. More about this image found in PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of t...
Images
LACTATING <span class="search-highlight">BREAST</span>  A: In the lactating <span class="search-highlight">breast</span>, the lobules expand and have n...
Published: 01 January 2024
LACTATING BREAST Figure 1-13 LACTATING BREAST A: In the lactating breast, the lobules expand and have numerous acini. B: The epithelial cells are enlarged, have prominent cytoplasmic vacuolization; there may be hobnailing of the nuclei into lumens of the acini. The myoepithelial cells become att... More about this image found in LACTATING BREAST A: In the lactating breast, the lobules expand and have n...
Images
MICROARCHITECTURE OF NORMAL ADULT FEMALE <span class="search-highlight">BREAST</span> TISSUE  A portion of an ext...
Published: 01 January 2024
MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE Figure 1-1 MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an extralobular duct (arrow), terminal duct, and lobules, in turn composed of acini, is seen. More about this image found in MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an ext...
Images
<span class="search-highlight">BREAST</span> LOBULES  Looser intralobular stroma and denser collagenous inter lob...
Published: 01 January 2024
BREAST LOBULES Figure 1-2 BREAST LOBULES Looser intralobular stroma and denser collagenous inter lobular stroma are seen. More about this image found in BREAST LOBULES Looser intralobular stroma and denser collagenous inter lob...
Images
ACINI OF THE <span class="search-highlight">BREAST</span>  The inner epithelial cell layer and the outer myoepith...
Published: 01 January 2024
ACINI OF THE BREAST Figure 1-4 ACINI OF THE BREAST The inner epithelial cell layer and the outer myoepithelial cell layer are depicted. The myoepithelial cells can be variably prominent; in this case they have abundant clear cytoplasm. More about this image found in ACINI OF THE BREAST The inner epithelial cell layer and the outer myoepith...
Images
LOBULAR INVOLUTION IN POSTMENOPAUSAL <span class="search-highlight">BREAST</span>  A few scattered atrophic acini...
Published: 01 January 2024
LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST Figure 1-14 LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini are dispersed in either fibrotic (A) or fatty stroma (B). More about this image found in LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini...
Images
POLYACRYLAMIDE HYDROGEL  A: Low-power image of a <span class="search-highlight">breast</span> core biopsy with po...
Published: 01 January 2024
POLYACRYLAMIDE HYDROGEL Figure 2-15 POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with pools of bluish material and calcifications present in the adipose tissue. B: On higher power, giant cells can be seen associated with the “mucin-like” material. Note the absence of epithe... More about this image found in POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with po...
Images
RADIATION EFFECT  A: At lower power, an irradiated <span class="search-highlight">breast</span> demonstrates atro...
Published: 01 January 2024
RADIATION EFFECT Figure 2-16 RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atrophic lobules with thickened basement membrane. Hyperchromatic nuclei are apparent in the cells within the lobules even at this power. B: On high power, this lobule has scattered epithelial cell... More about this image found in RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atro...
Images
CYST WALL  A core needle biopsy specimen of a <span class="search-highlight">breast</span> cyst shows fibrosis of...
Published: 01 January 2024
CYST WALL Figure 2-20 CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of the cyst wall and the attenuated epithelial lining, particularly where it runs along the edges of the core biopsy sample. More about this image found in CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of...
Images
SQUAMOUS METAPLASIA  Squamous metaplasia may be seen in a variety of <span class="search-highlight">breast</span>...
Published: 01 January 2024
SQUAMOUS METAPLASIA Figure 2-23 SQUAMOUS METAPLASIA Squamous metaplasia may be seen in a variety of breast lesions; this example involves an intraductal papilloma. More about this image found in SQUAMOUS METAPLASIA Squamous metaplasia may be seen in a variety of breast...
Images
INVASIVE <span class="search-highlight">BREAST</span> CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1  This low-power i...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 Figure 8-1 INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 This low-power image shows a tumor composed of well-formed tubules with cells that have round, regular nuclei; no mitoses are present. More about this image found in INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 This low-power i...
Images
INVASIVE <span class="search-highlight">BREAST</span> CARCINOMA, NST, GRADE 2  This tumor is composed of a mix of...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NST, GRADE 2 Figure 8-2 INVASIVE BREAST CARCINOMA, NST, GRADE 2 This tumor is composed of a mix of tubules and solid nests. The tumor cell nuclei display greater variability than the prior case. More about this image found in INVASIVE BREAST CARCINOMA, NST, GRADE 2 This tumor is composed of a mix of...
Images
INVASIVE <span class="search-highlight">BREAST</span> CARCINOMA, NST, GRADE 3  There are sheets of tumor cells wi...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NST, GRADE 3 Figure 8-3 INVASIVE BREAST CARCINOMA, NST, GRADE 3 There are sheets of tumor cells with large pleomorphic nuclei. Zones of necrosis are present; while not a criterion of grading, necrosis is more likely to be seen in grade 3 and triple-negative breast cance... More about this image found in INVASIVE BREAST CARCINOMA, NST, GRADE 3 There are sheets of tumor cells wi...
Images
INVASIVE <span class="search-highlight">BREAST</span> CARCINOMA, NST, GRADE 1  A: Over 75 percent of this tumor i...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NST, GRADE 1 Figure 8-10 INVASIVE BREAST CARCINOMA, NST, GRADE 1 A: Over 75 percent of this tumor is composed of tubules. B: The tumor cell nuclei are of low nuclear grade; no mitotic figures are seen. C: As would be anticipated, the tumor is strongly and diffusely es... More about this image found in INVASIVE BREAST CARCINOMA, NST, GRADE 1 A: Over 75 percent of this tumor i...
Images
INVASIVE <span class="search-highlight">BREAST</span> CARCINOMA, NST, GRADE 2  A: This tumor is composed of an ad...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NST, GRADE 2 Figure 8-11 INVASIVE BREAST CARCINOMA, NST, GRADE 2 A: This tumor is composed of an admixture of glands and solid nests. B,C: The tumor cell nuclei are intermediate grade (B) and scattered mitotic figures are appreciated at high (C) power. More about this image found in INVASIVE BREAST CARCINOMA, NST, GRADE 2 A: This tumor is composed of an ad...