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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of microorganisms on FFPE tissue using molecular techniques is not as sensitive as when performed on fresh tissue ( 11 , 12 ). Illustrative Case: A 68-year-old woman presents with altered mental status. She has a history of breast cancer, treated with lumpectomy and radiation 10 years previously. One week before...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... transmission is rare but has been documented, including transmission across the placenta, to infants through breast milk, and via the sexual route ( 4 ). Individuals at highest risk for infection are veterinarians and abattoir workers, although laboratory personnel that handle Brucella cultures...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... be acquired through mosquito bites, blood transfusions, organ transplants, breast milk, and transplacentally Japanese encephalitis JEV Aedes, Anopheles and Culex spp Birds Asia, Australia, and Eastern Pacific Cyclical major outbreaks occur in the regions, usually during the rainy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of bacillary dysentery relies on safe water supplies and sanitation, hand washing, good personal hygiene, and in infants, breast feeding ( 16 ). Vaccines against Shigella spp are currently being developed. Antibiotics and supportive measures are the cornerstones of bacillary dysentery therapy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Invasive breast carcinoma is a broad category of epithelial malignancies, most with overlapping clinical and imaging characteristics, as well as macroscopic features, but each with varied microscopic features. It is these latter characteristics that are used to classify breast carcinomas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...The prepubertal breast is composed of stroma and lactiferous ducts; little branching of the ducts is seen, and lobuloalveolar differentiation is rudimentary. With the onset of puberty in girls, the ducts elongate, branch, and begin to develop lobuloacinar units under the combined influence...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Lesions occurring in the female breast may also occur in the male breast, albeit with far lesser frequency. Myofibroblastoma is one lesion that had historically been reported to be more frequent in males, but is now recognized to occur with equal frequency in men and women. Other entities...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...As with any field in pathology, appropriate specimen processing is critical to tissue evaluation. Breast tissue, in particular, due to its inherently fatty composition requires special attention to adequate fixation prior to processing in order to ensure optimal microscopic examination and accuracy...
Images
Published: 01 February 2024
BREAST NEVUS Figure 5-7 BREAST NEVUS A: The compound melanocytic nevus shows nests of varying size and shape with a junctional shoulder. B: Large nests of melanocytes are seen with cell dyscohesion (arrow). More about this image found in BREAST NEVUS A: The compound melanocytic nevus shows nests of varying size...
Images
Published: 01 February 2024
PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE Figure 8-23 PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of the stroma of the breast by pigmented melanocytes. B: The melanocytes display spindle, epithelioid, and dendritic features and are cytologically bland. More about this image found in PLAQUE-TYPE BLUE NEVUS INVOLVING BREAST TISSUE A: Diffuse involvement of t...
Images
Published: 01 January 2024
LACTATING BREAST Figure 1-13 LACTATING BREAST A: In the lactating breast, the lobules expand and have numerous acini. B: The epithelial cells are enlarged, have prominent cytoplasmic vacuolization; there may be hobnailing of the nuclei into lumens of the acini. The myoepithelial cells become att... More about this image found in LACTATING BREAST A: In the lactating breast, the lobules expand and have n...
Images
Published: 01 January 2024
MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE Figure 1-1 MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an extralobular duct (arrow), terminal duct, and lobules, in turn composed of acini, is seen. More about this image found in MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an ext...
Images
Published: 01 January 2024
BREAST LOBULES Figure 1-2 BREAST LOBULES Looser intralobular stroma and denser collagenous inter lobular stroma are seen. More about this image found in BREAST LOBULES Looser intralobular stroma and denser collagenous inter lob...
Images
Published: 01 January 2024
ACINI OF THE BREAST Figure 1-4 ACINI OF THE BREAST The inner epithelial cell layer and the outer myoepithelial cell layer are depicted. The myoepithelial cells can be variably prominent; in this case they have abundant clear cytoplasm. More about this image found in ACINI OF THE BREAST The inner epithelial cell layer and the outer myoepith...
Images
Published: 01 January 2024
LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST Figure 1-14 LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini are dispersed in either fibrotic (A) or fatty stroma (B). More about this image found in LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini...
Images
Published: 01 January 2024
POLYACRYLAMIDE HYDROGEL Figure 2-15 POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with pools of bluish material and calcifications present in the adipose tissue. B: On higher power, giant cells can be seen associated with the “mucin-like” material. Note the absence of epithe... More about this image found in POLYACRYLAMIDE HYDROGEL A: Low-power image of a breast core biopsy with po...
Images
Published: 01 January 2024
RADIATION EFFECT Figure 2-16 RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atrophic lobules with thickened basement membrane. Hyperchromatic nuclei are apparent in the cells within the lobules even at this power. B: On high power, this lobule has scattered epithelial cell... More about this image found in RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atro...
Images
Published: 01 January 2024
CYST WALL Figure 2-20 CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of the cyst wall and the attenuated epithelial lining, particularly where it runs along the edges of the core biopsy sample. More about this image found in CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of...
Images
Published: 01 January 2024
SQUAMOUS METAPLASIA Figure 2-23 SQUAMOUS METAPLASIA Squamous metaplasia may be seen in a variety of breast lesions; this example involves an intraductal papilloma. More about this image found in SQUAMOUS METAPLASIA Squamous metaplasia may be seen in a variety of breast...
Images
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 Figure 8-1 INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 This low-power image shows a tumor composed of well-formed tubules with cells that have round, regular nuclei; no mitoses are present. More about this image found in INVASIVE BREAST CARCINOMA, NO SPECIAL TYPE (NST), GRADE 1 This low-power i...
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