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STRESS CARDIOMYOPATHY: “<span class="search-highlight">BRAIN</span> DEATH” LESIONS  There are small groups of myo...
Published: 15 November 2023
STRESS CARDIOMYOPATHY: “BRAIN DEATH” LESIONS Figure 18-7 STRESS CARDIOMYOPATHY: “BRAIN DEATH” LESIONS There are small groups of myocytes (arrows) with flocculent necrotic cytoplasm surrounded by scant mononuclear inflammatory cells. More about this image found in STRESS CARDIOMYOPATHY: “BRAIN DEATH” LESIONS There are small groups of myo...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... al . Primary melanoma of the leptomeninges with BAP1 expression-loss in the setting of a nevus of Ota: a clinical, morphological and genetic study of 2 cases . Brain Pathol   2016 ; 26 : 547 - 50 . 17. Tse   JY , Walls   BE , Pomerantz   H , et al . Melanoma arising in a nevus...
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HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION  <em>Streptococcus pneu</em>...
Published: 15 November 2023
HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Figure 39-50 HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Streptococcus pneumoniae meningitis, with multiple purulent exudates, was the cause of death in an infant. (Inferior aspect of brain.) More about this image found in HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Streptococcus pneu...
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STRESS CARDIOMYOPATHY  Foci of myocyte loss, with minimal inflammation and ...
Published: 15 November 2023
STRESS CARDIOMYOPATHY Figure 18-8 STRESS CARDIOMYOPATHY Foci of myocyte loss, with minimal inflammation and myocyte necrosis, are seen in a patient who developed left ventricular dysfunction following chemotherapy. The focus in the middle of the field is a typical “brain death” lesion. More about this image found in STRESS CARDIOMYOPATHY Foci of myocyte loss, with minimal inflammation and ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch18
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... CARDIOMYOPATHY: “BRAIN DEATH” LESIONS Figure 18-7 STRESS CARDIOMYOPATHY: “BRAIN DEATH” LESIONS There are small groups of myocytes (arrows) with flocculent necrotic cytoplasm surrounded by scant mononuclear inflammatory cells. STRESS CARDIOMYOPATHY Figure 18-8 STRESS CARDIOMYOPATHY Foci of myocyte loss...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... Grade 3, IBC NST b ER, PR, HER2 negative Solid growth pattern, circumscribed margin, necrosis or fibrosis TIL rich Basal-like More lung/brain mets Tubo-ovarian Familial breast ovarian cancer 2 BRCA2 DNA repair Grade 2 or 3, IBC NST, tubular, cribriform, mucinous, ILC, PILC ER...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch20
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... Deceleration time (DT) >200 ms Prolonged isovolumetric relations time >80 ms Supportive Prolonged QT interval Abnormal chronotropic response Electromechanical uncoupling Enlarged left atrium Cardiac hypertrophy Increased brain natriuretic peptide Increased troponin I a Data from reference 28...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch41
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...   1989 ; 91 : 221 - 7 . 91. Altundag   MB , Ertas   G , Ucer   AR , et al . Brain metastasis of cardiac myxoma: case report and review of the literature . J Neurooncol   2005 ; 75 : 181 - 4 . 92. Terada   Y , Wanibuchi   Y , Noguchi   M , Mitsui   T . Metastatic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch53
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... symptoms . Oxf Med Case Reports   2017 ; 2017 : omx031 . 15. Siontis   BL , Zhao   L , Leja   M , et al . Primary cardiac sarcoma: a rare, aggressive malignancy with a high propensity for brain metastases . Sarcoma   2019 ; 2019 : 1960593 . 16. Fu   X , Niu   W , Li   J...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... and Presentations. Most patients present with cardiac symptoms, including heart failure, cyanosis, peripheral edema, dyspnea, and syncope. Because cardiac IMTs are endocardial-based lesions, pericardial effusions are uncommon ( 10 ). The second most frequent presentation involves systemic embolization to the brain...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch43
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... In one series, even though only 46 percent of tumors could be completely resected, subsequent regression and sustained symptom-free survival was typical, with no late deaths, and only one death due to postoperative brain hemorrhage ( 18 ). The prognosis for patients with in utero diagnosis of cardiac...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch54
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... with cardiac tamponade followed by cerebral hemorrhage with brain metastases . Jpn J Thorac Cardiovasc Surg   2006 ; 54 : 528 - 31 . 31. Kim   DM , Hong   JH , Kim   SY , et al . Primary cardiac angiosarcoma presenting with cardiac tamponade . Korean Circ J   2010 ; 40 : 86 - 9 . 32...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch29
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... the heart, kidneys, and brain ( Table 29-1 ). Effects on the heart are discussed in chapter 20 . Hypertension also affects retinal vessels, in the form of hypertensive retinopathy ( 52 ). Hypertension is the most significant risk factor for stroke, both hemorrhagic and ischemic, but especially for cerebral...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch38
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... septum. As the right ventricle begins to fail, the systemic venous circulation becomes engorged, and mild congestive hepatosplenomegaly may result. Microscopic features of hypoperfusion injury commonly affect the kidneys, liver, brain, and heart. Pathology of Interventions. If left untreated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch39
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... 55 Immunity or Infection related  Abnormal thymic involution 25 10  Tracheobronchitis 10 15  Bacteremia or fungemia 15 30 Symmetric organ anomalies cBrain 45 0  Kidneys 15 0  Genitals 15 0 a Based on averages from references 35 , 36...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch08
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of small particles from mural thrombi may be asymptomatic, embolization of larger fragments often leads to symptomatic ischemia or infarction, and may affect systemic organs (e.g., brain, heart). Thromboemboli are observed histologically at autopsy in about a third of cases but are apparent clinically...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... nontransmural infarcts Acute transmural infarcts, following successful thrombolytic therapy Elevated catecholamine levels:  High-dose pressors  Stress cardiomyopathy  Acute nontransmural infarcts  Stress cardiomyopathy  Pheochromocytoma  Acute subarachnoid hemorrhage  Acute brain death  Septic shock  Cocaine...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch21
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... mitral valvulopathy ( 3 ). Aschoff nodules are seen in any of the layers of the heart, including the valves. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects a variety of organ systems, namely, the kidney, brain, and heart. The diagnosis relies on the clinical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch19
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... myopathy: clinical, morphological and genetic studies in 63 patients . Brain   2004 ; 127 : 439 - 51 . 17. Arbustini   E , Morbini   P , Grasso   M , et al . Restrictive cardiomyopathy, atrioventricular block and mild to subclinical myopathy in patients with desmin-immunoreactive...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... people. The diagnosis is suggested by brain magnetic resonance imaging (MRI), angiography, and abnormal cerebral spinal fluid (CSF) findings, but biopsy is the gold standard ( 86 ). There are three main pathologic patterns: granulomatous, often with β-4 amyloid deposits, lymphocytic, and PAN-like...