USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES Figure 1-2 USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES A,B: Bone marrow H&E (A) and Grocott methenamine silver (B) stains. The latter shows numerous budding Histoplasma capsulatum yeasts. C–E: H&E stain (C,D) on a pituitary gland specimen showing histologic findings suspicious for tissue pathogens. A strongly positive von Kossa calcium stain (E), however, confirms the suspicious deposits as calcifications and excludes infectious microorganisms. More about this image found in USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES A,B: Bone ma...

PARVOVIRUS B19 Figure 8-3 PARVOVIRUS B19 Bone marrow histology shows a hypercellular appearance, with intranuclear parvovirus B19 inclusions affecting erythroid precursors (A, center and B, bottom). More about this image found in PARVOVIRUS B19 Bone marrow histology shows a hypercellular appearance, wit...

EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Figure 8-9 EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Bone marrow trephine biopsy (A,B) and aspirate (C,D). More about this image found in EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Bone marrow trephine bio...

GELATINOUS TRANSFORMATION OF BONE MARROW INTERSTITIUM IN HIV Figure 9-4 GELATINOUS TRANSFORMATION OF BONE MARROW INTERSTITIUM IN HIV Serous or mucoid-like replacement of bone marrow tissue and hemopoietic atrophy are seen. More about this image found in GELATINOUS TRANSFORMATION OF BONE MARROW INTERSTITIUM IN HIV Serous or muc...

HEMOPHAGOCYTOSIS OF BONE MARROW Figure 9-5 HEMOPHAGOCYTOSIS OF BONE MARROW Macrophages are abundant and enlarged, and engulf erythrocytes and nucleated cells. More about this image found in HEMOPHAGOCYTOSIS OF BONE MARROW Macrophages are abundant and enlarged, and...

BRUCELLOSIS Figure 14-5 BRUCELLOSIS Bone marrow involvement in brucellosis demonstrates histiocyte aggregates and poor granuloma formation. More about this image found in BRUCELLOSIS Bone marrow involvement in brucellosis demonstrates histiocyte...

BARTONELLA-ASSOCIATED PELIOSIS Figure 17-5 BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone marrow (B) characteristic randomly distributed and cystic, blood-filled cavities are seen, which typify this disorder. Warthin-Starry silver stain (C) demonstrates numerous etiologic bacteria. More about this image found in BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone ...

COCCIDIOIDOMYCOSIS Figure 21-6 COCCIDIOIDOMYCOSIS Chronic complications include lung cavitation (A), disfiguring skin lesions (B), and bone dissemination (hand, C). (Courtesy of the CDC PHIL) More about this image found in COCCIDIOIDOMYCOSIS Chronic complications include lung cavitation (A), disf...

PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS Figure 8-4 PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS The HIV patient has a hypercellular bone marrow (A) with numerous large atypical pronormoblasts (B). More about this image found in PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS The HIV patient has a ...

OROCERVICOFACIAL ACTINOMYCOSIS Figure 12-28 OROCERVICOFACIAL ACTINOMYCOSIS A: Preauricular scarring and sinus formation are evident. B: Chest X-ray in thoracic disease (right) shows lung parenchymal, soft tissue, and bone destruction. (Courtesy of the CDC PHIL) More about this image found in OROCERVICOFACIAL ACTINOMYCOSIS A: Preauricular scarring and sinus formatio...