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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Melanoma may develop in association with a blue nevus or simulate histopathologically the appearance of a blue nevus (blue nevus-like melanoma) ( 1 – 7 ). Such tumors have historically been referred to as “malignant blue nevus” ( 2 ). “Malignant blue tumor” is a better term to avoid...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...Blue nevus (BN) and dermal melanocytosis share clinical, histopathologic, immunohistochemical, and molecular features ( 1 , 2 ). Clinically, most lesions are characterized by bluish discoloration. Histologically, there is an intrastromal proliferation of slender fusiform...
Images
COMMON <span class="search-highlight">BLUE</span> NEVUS  Common <span class="search-highlight">blue</span> nevus (BN), uniformly pigmented, extends thr...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-5 COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends through the entire dermis into the superficial subcutis. There is associated mild stromal fibrosis. More about this image found in COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends thr...
Images
CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID <span class="search-highlight">BLUE</span> NEVUS-LIKE PN  A: Low-p...
Published: 01 February 2024
CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN Figure 2-18 CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-power view of a portion of a giant CMN that contains a pigmented nodule. B: The pigmented nodule is composed of large epithelioid melanocytes and... More about this image found in CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-p...
Images
COMMON <span class="search-highlight">BLUE</span> NEVUS  There is a small collection of fusiform and dendritic me...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-2 COMMON BLUE NEVUS There is a small collection of fusiform and dendritic melanocytes with a few melanophages in the superficial reticular dermis. More about this image found in COMMON BLUE NEVUS There is a small collection of fusiform and dendritic me...
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COMMON <span class="search-highlight">BLUE</span> NEVUS  Small lesion of pigmented fusiform and dendritic melanoc...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-3 COMMON BLUE NEVUS Small lesion of pigmented fusiform and dendritic melanocytes and scattered melanophages. These cells are present in the superficial reticular dermis in association with pilar erector smooth muscle bundles. More about this image found in COMMON BLUE NEVUS Small lesion of pigmented fusiform and dendritic melanoc...
Images
COMMON <span class="search-highlight">BLUE</span> NEVUS  A: Variably dense aggregates of pigmented melanocytes ar...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-4 COMMON BLUE NEVUS A: Variably dense aggregates of pigmented melanocytes are distributed around follicular units occupying a larger area in the reticular dermis. B: There are slender fusiform melanocytes with finely granular cytoplasmic melanin pigment and small oval ... More about this image found in COMMON BLUE NEVUS A: Variably dense aggregates of pigmented melanocytes ar...
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COMMON <span class="search-highlight">BLUE</span> NEVUS  A: Papular exophytic silhouette of a pigmented intraderm...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-6 COMMON BLUE NEVUS A: Papular exophytic silhouette of a pigmented intradermal melanocytic nevus. B: Slender fusiform and dendritic melanocytes wrap around collagen bundles. C: Dendritic melanocytes carry fine melanin granules in the cytoplasm in contrast to the large... More about this image found in COMMON BLUE NEVUS A: Papular exophytic silhouette of a pigmented intraderm...
Images
SCLEROSING <span class="search-highlight">BLUE</span> NEVUS  A: Much of the superficial portion of the tumor is p...
Published: 01 February 2024
SCLEROSING BLUE NEVUS Figure 8-7 SCLEROSING BLUE NEVUS A: Much of the superficial portion of the tumor is paucicellular, with abundant fibrous stroma and little melanin pigment deposition. Its deep portion contains more heavily pigmented and denser aggregates of melanocytes. B: Paucimelanotic sp... More about this image found in SCLEROSING BLUE NEVUS A: Much of the superficial portion of the tumor is p...
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SCLEROSING <span class="search-highlight">BLUE</span> NEVUS  A: Small amelanotic fibrosing spindle cell lesion in...
Published: 01 February 2024
SCLEROSING BLUE NEVUS Figure 8-8 SCLEROSING BLUE NEVUS A: Small amelanotic fibrosing spindle cell lesion in the superficial dermis. B: The spindle cells are strongly and diffusely immunoreactive for Melan-A. C: The tumor cells display cytologically bland fibroblast-like features, simulating a f... More about this image found in SCLEROSING BLUE NEVUS A: Small amelanotic fibrosing spindle cell lesion in...
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SCLEROSING AND CELLULAR <span class="search-highlight">BLUE</span> NEVUS  A: Sclerosing spindle cell nodule is in...
Published: 01 February 2024
SCLEROSING AND CELLULAR BLUE NEVUS Figure 8-9 SCLEROSING AND CELLULAR BLUE NEVUS A: Sclerosing spindle cell nodule is in the dermis. Most of the superficial part of the tumor is paucicellular, typical of a sclerosing BN, but its lower half contains areas of hypercellularity. B: Paucicellular fib... More about this image found in SCLEROSING AND CELLULAR BLUE NEVUS A: Sclerosing spindle cell nodule is in...
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<span class="search-highlight">BLUE</span> NEVUS WITH EPITHELIOID CELL FEATURES  A: Heavily pigmented intradermal...
Published: 01 February 2024
BLUE NEVUS WITH EPITHELIOID CELL FEATURES Figure 8-10 BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal melanocytic nevus. B,C: Most of the pigmented tumor cells are epithelioid in appearance. A minor population of melanocytes displays conventional BN-like fusiform and d... More about this image found in BLUE NEVUS WITH EPITHELIOID CELL FEATURES A: Heavily pigmented intradermal...
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COMBINED <span class="search-highlight">BLUE</span> NEVUS  Biphenotypic intradermal melanocytic nevus with a mixe...
Published: 01 February 2024
COMBINED BLUE NEVUS Figure 8-11 COMBINED BLUE NEVUS Biphenotypic intradermal melanocytic nevus with a mixed population of conventional small epithelioid melanocytes and a pigmented population with fusiform melanocytes with common BN-like features. More about this image found in COMBINED BLUE NEVUS Biphenotypic intradermal melanocytic nevus with a mixe...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS  A: Pigmented melanocytic nevus with fibrotic bulbous t...
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-13 CELLULAR BLUE NEVUS A: Pigmented melanocytic nevus with fibrotic bulbous tongue-like extensions into the subcutis. Hypercellular nodules are present in the deep portion of the tumor. B: Densely cellular spindle cell nodule is surrounded by heavily pigmented fusifo... More about this image found in CELLULAR BLUE NEVUS A: Pigmented melanocytic nevus with fibrotic bulbous t...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS  A: Biphasic tumor with background fibrosis and areas o...
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-14 CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas of high and low cell density. B: Dense aggregates of cytologically bland melanocytes with elongated nuclei and pale cytoplasm, with admixed melanophages and adjacent pigmented spindle cells i... More about this image found in CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas o...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS  A: Pigmented tumor with an exophytic surface nodule pe...
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-15 CELLULAR BLUE NEVUS A: Pigmented tumor with an exophytic surface nodule penetrates into the superficial subcutis. B: Fascicles of spindle and epithelioid cells with delicate cytoplasmic granules are present in a fibrous stroma, admixed with clusters of melanophage... More about this image found in CELLULAR BLUE NEVUS A: Pigmented tumor with an exophytic surface nodule pe...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS WITH CYSTIC DEGENERATION  Nodule of melanocytes has a p...
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Figure 8-16 CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Nodule of melanocytes has a peripheral rim of fibrous stroma and central loose edematous stroma and hemorrhage. Some of the vessels have a hyalinized rim. More about this image found in CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Nodule of melanocytes has a p...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS WITH STROMAL EDEMA  Small nodular aggregates and nests ...
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH STROMAL EDEMA Figure 8-17 CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests of cytologically bland melanocytes are seen in a background of edematous stroma with scattered melanophages. More about this image found in CELLULAR BLUE NEVUS WITH STROMAL EDEMA Small nodular aggregates and nests ...
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CELLULAR <span class="search-highlight">BLUE</span> NEVUS WITH MULTINUCLEATED MELANOCYTES  Several multinucleated...
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH MULTINUCLEATED MELANOCYTES Figure 8-18 CELLULAR BLUE NEVUS WITH MULTINUCLEATED MELANOCYTES Several multinucleated melanocytes are present. More about this image found in CELLULAR BLUE NEVUS WITH MULTINUCLEATED MELANOCYTES Several multinucleated...