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Figure 21-5
Published: 01 February 2024
SMALL ROUND CELL BLASTIC MELANOMA Figure 21-5 SMALL ROUND CELL BLASTIC MELANOMA The tumor cells of this melanoma have a primitive round cell appearance. More about this image found in SMALL ROUND CELL BLASTIC MELANOMA The tumor cells of this melanoma have a ...
Images
Figure 20-3
Published: 01 February 2024
surrounded by a congenital compound nevus. C: The surrounding nevus shows evidence of maturation and bland cytology. D: The melanocytes cells have a “blastic” small round cell appearance. More about this image found in NODULAR MELANOMA ASSOCIATED WITH A LARGE CONGENITAL MELANOCYTIC NEVUS A: T...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... and subsequent soft tissue metastasis. FOLLICULOTROPIC MELANOMA Figure 21-4 FOLLICULOTROPIC MELANOMA Melanoma in situ is prominently present within hair follicles and also in the perifollicular stroma. SMALL ROUND CELL BLASTIC MELANOMA Figure 21-5 SMALL ROUND CELL BLASTIC MELANOMA The tumor cells...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-02
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...) increased terminal hairs ( 1 ). Most nevi show good evidence of maturation ( fig. 2-7 ). In some large or giant congenital nevi, the melanocytes have a “blastic” lymphocyte-like appearance ( fig. 2-8 ). PNs are cellular aggregates of melanocytes that develop within a CMN ( 9 , 15 ). They stand out from...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-20
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... of the lesion shows expansile nodular growth surrounded by a congenital compound nevus. C: The surrounding nevus shows evidence of maturation and bland cytology. D: The melanocytes cells have a “blastic” small round cell appearance. NODULAR MELANOMA ASSOCIATED WITH A GIANT MELANOCYTIC NEVUS Figure 20-4...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-16
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... . Int J Gynecol Pathol   1997 ; 16 : 79 - 80 . 232. Clement   PB , Young   RH , Scully   RE . Nontropho-blastic pathology of the female genital tract and peritoneum associated with pregnancy . Semin Diagn Pathol   1989 ; 6 : 372 - 406 . 233. Lisa   JR , Rubin   IC...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-15
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... recognizable radiographically; this is quickly walled off by foamy macrophages. Later, the foamy macrophages are replaced by smaller macrophages that may contain iron pigment and are further replaced by myofibro-blastic cells. Ultimately, the cellular granulation tissue is replaced by hyalinized fibrous tissue...
Images
Figure 6-1
Published: 01 June 2022
PRIMARY EFFUSION LYMPHOMA Figure 6-1 PRIMARY EFFUSION LYMPHOMA Sheets of monotonous large blastic lymphoid cells are present within a cell block from a pleural effusion. More about this image found in PRIMARY EFFUSION LYMPHOMA Sheets of monotonous large blastic lymphoid cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-09
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... basic morphologic types according to the degree of myeloid cell maturation: blastic, immature, and differentiated ( 67 , 81 – 83 ). The blastic form consists of myeloblasts with scant to moderate amounts of basophilic cytoplasm; the nuclear chromatin is fine, and nucleoli are conspicuous ( fig. 9-24...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Published: 01 June 2022
10.55418/9781933477190-6
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
...PRIMARY EFFUSION LYMPHOMA Figure 6-1 PRIMARY EFFUSION LYMPHOMA Sheets of monotonous large blastic lymphoid cells are present within a cell block from a pleural effusion. PRIMARY EFFUSION LYMPHOMA Figure 6-2 PRIMARY EFFUSION LYMPHOMA The cells have prominent single nucleoli and focally show...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Published: 01 June 2022
10.55418/9781933477190-8
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... heterogeneous, and both plasma cells and larger blastic cells are seen ( fig. 8-3 ), although this does not indicate that the infiltrate is malignant. Plasma cells may be present and, if abundant, IgG4-related disease should be considered (see below) ( 17 ). Chronic follicular pleuritis has also been described...
Images
Figure 5-5
Published: 01 October 2021
CONVENTIONAL OSTEOSARCOMA Figure 5-5 CONVENTIONAL OSTEOSARCOMA Frontal (left) and lateral (right) radiographs of the distal femur show a destructive lytic and blastic tumor extending into the soft tissues with associated pathologic fracture and displacement of the posterior cortex by attached More about this image found in CONVENTIONAL OSTEOSARCOMA Frontal (left) and lateral (right) radiographs o...
Images
Figure 1-315
Published: 01 September 2021
TRICHOBLASTOMA Figure 1-315 TRICHOBLASTOMA The tumor cells have a blastic appearance, with large round nuclei with open chromatin, small nucleoli, and scant cytoplasm. Mitotic activity is present. More about this image found in TRICHOBLASTOMA The tumor cells have a blastic appearance, with large round...
Images
Figure 1-321
Published: 01 September 2021
CUTANEOUS LYMPHADENOMA Figure 1-321 CUTANEOUS LYMPHADENOMA Clear cell change of the blastic tumor cells with admixed small lymphocytes. More about this image found in CUTANEOUS LYMPHADENOMA Clear cell change of the blastic tumor cells with a...
Images
Figure 3-130
Published: 01 September 2021
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Figure 3-130 BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Low-power view shows a patchy but focally dense infiltrate throughout the dermis, sparing the epidermis. More about this image found in BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Low-power view shows a patchy...
Images
Figure 3-131
Published: 01 September 2021
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Figure 3-131 BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Involvement of subcutaneous fat. More about this image found in BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Involvement of subcutaneous f...
Images
Figure 3-132
Published: 01 September 2021
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Figure 3-132 BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM A diffuse infiltrate of blast cells fills the dermis. Numerous mitotic figures are seen. More about this image found in BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM A diffuse infiltrate of blast...
Images
Figure 3-133
Published: 01 September 2021
TYPICAL BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM PHENOTYPE Figure 3-133 TYPICAL BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM PHENOTYPE The neoplastic cells are positive for CD4 (A), CD56 (B), and CD123 (C). More about this image found in TYPICAL BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM PHENOTYPE The neoplas...
Images
Figure 3-134
Published: 01 September 2021
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Figure 3-134 BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM A: CD68 stains tumor-associated macrophages and also show dot-like positivity in some of the neoplastic plasmacytoid dendritic cells (arrows). B: One case shows uniform expression of TdT More about this image found in BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM A: CD68 stains tumor-associat...
Images
Figure 3-135
Published: 01 September 2021
DIFFERENTIATING CUTANEOUS MYELOID SARCOMA FROM BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM Figure 3-135 DIFFERENTIATING CUTANEOUS MYELOID SARCOMA FROM BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM This example of myeloid sarcoma shows strong staining for CD4 (A) and CD56 (B). However, markers More about this image found in DIFFERENTIATING CUTANEOUS MYELOID SARCOMA FROM BLASTIC PLASMACYTOID DENDRIT...