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Images
Figure 2-5
Published: 01 December 2024
ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY Figure 2-5 ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY A: Uncircumscribed adrenal cortical tissue was present between the renal capsule and a renal subcortical cyst. A small amount of normal kidney is present at left. The empty space More about this image found in ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY A: Uncircumscribed adrena...
Images
Figure 5-15
Published: 01 December 2024
POST-FINE NEEDLE ASPIRATION BIOPSY INVOLUTIVE CHANGES IN AN INCIDENTAL ADRENAL CORTICAL ADENOMA Figure 5-15 POST-FINE NEEDLE ASPIRATION BIOPSY INVOLUTIVE CHANGES IN AN INCIDENTAL ADRENAL CORTICAL ADENOMA Incidental nonfunctional adrenal cortical adenoma in a 73-year-old man who had gallstones More about this image found in POST-FINE NEEDLE ASPIRATION BIOPSY INVOLUTIVE CHANGES IN AN INCIDENTAL ADRE...
Images
Figure 11-29
Published: 01 December 2024
DIFFERENTIATING NEUROBLASTOMA Figure 11-29 DIFFERENTIATING NEUROBLASTOMA Left adrenal biopsy of 13-month-old boy shows morphologically heterogeneous tumor with varying ganglion cell differentiation, next to areas with neuroblasts, separated by neuropil. More about this image found in DIFFERENTIATING NEUROBLASTOMA Left adrenal biopsy of 13-month-old boy show...
Images
Figure 11-30
Published: 01 December 2024
GANGLIONEUROBLASTOMA INTERMIXED Figure 11-30 GANGLIONEUROBLASTOMA INTERMIXED Biopsy of paravertebral mass in 11-year-old girl shows areas of schwannian stroma, intermingled with areas of immature stroma containing cells with varying differentiation toward ganglion cells, but also including More about this image found in GANGLIONEUROBLASTOMA INTERMIXED Biopsy of paravertebral mass in 11-year-ol...
Images
Figure 11-37
Published: 01 December 2024
NEUROBLASTOMA METASTATIC TO BONE AND BONE MARROW Figure 11-37 NEUROBLASTOMA METASTATIC TO BONE AND BONE MARROW This trephine biopsy shows extensive involvement by NB, which is even appreciated without immunohistochemistry. More about this image found in NEUROBLASTOMA METASTATIC TO BONE AND BONE MARROW This trephine biopsy show...
Images
Figure 12-25
Published: 01 December 2024
ADENOCARCINOMA METASTATIC TO ADRENAL GLAND Figure 12-25 ADENOCARCINOMA METASTATIC TO ADRENAL GLAND A: Core needle biopsy of an adrenal mass in a patient with non-small cell lung carcinoma. The tumor replaces much of adrenal tissue, with only small nests of residual pale-staining cortical cells More about this image found in ADENOCARCINOMA METASTATIC TO ADRENAL GLAND A: Core needle biopsy of an adr...
Images
Figure 6-31
Published: 01 December 2024
SF1 IN ADRENAL CORTICAL CARCINOMA Figure 6-31 SF1 IN ADRENAL CORTICAL CARCINOMA The diagnosis of metastatic adrenal cortical carcinoma in this transbronchial fine needle aspiration biopsy of a perihilar lymph node (A) is supported by positive nuclear staining for SF1 (B). More about this image found in SF1 IN ADRENAL CORTICAL CARCINOMA The diagnosis of metastatic adrenal cort...
Images
Images
Figure 3-13
Published: 01 December 2024
dexamethasone. Skull X rays showed no abnormalities of the sella turcica. Following surgical removal of this 3-cm pheochromocytoma, hirsutism regressed and steroid levels normalized. Surgery was complicated by hypotensive episodes. The hyperplastic adrenal cortex was largely lipid depleted. Biopsy More about this image found in ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female p...
Images
Figure 12-21
Published: 01 December 2024
aspiration biopsy of enlarged adrenal gland shows numerous round to ovoid yeast forms of H. capsulatum. Some organisms are isolated and single while others have a budding configuration. More about this image found in ADRENAL HISTOPLASMOSIS A: Transverse section of an enlarged adrenal gland ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... as malignant rhabdoid tumor on the basis of morphology and loss of BRG1 immunostaining, until resection showed foci of ganglion cell differentiation next to remaining undifferentiated areas and extensive necrosis. (Images are from the initial biopsy specimen.) Neuropil is recognized as slightly eosinophilic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ), but in many instances diagnosis is by fine needle aspiration biopsy or examination of surgically resected specimens. Nonendocrine adrenal lesions are now most often discovered as incidentalomas, defined as masses larger than 1 cm detected during imaging for unrelated conditions. The strictest definition...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cell necrosis in the presence of hemorrhage or involutive changes (possibly as the consequence of fine needle biopsy) may be erroneously interpreted Cell cytoplasm Eosinophilic homogeneous cytoplasm devoid of vacuoles is a morphologic sign of loss of differentiation Eosinophilic cytoplasm should...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... risk ( 64 ). Ki-67 labeling has been assessed in only a few cases, and may be either low or high in tumors that metastasize. Cytologic Findings Biopsy of abdominal/retroperitoneal paragangliomas is generally not advised because of potential bleeding or catecholamine release ( 133 ), but sometimes...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...) and negative staining for PAX2 and PAX8 identifies adrenal tissue in most cases ( fig. 2-5 ) ( 16 ). An unusual example in a dysplastic pediatric kidney is shown in figure 2-6 . ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY Figure 2-5 ADRENAL CORTICAL TISSUE IN A DONOR KIDNEY BIOPSY A: Uncircumscribed...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... levels normalized. Surgery was complicated by hypotensive episodes. The hyperplastic adrenal cortex was largely lipid depleted. Biopsy of the opposite hyperplastic adrenal gland was identical. Treatment. The treatment of adrenal cortical hyperplasia in patients with ACTH-dependent Cushing syndrome...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... atrophy caused by suppression of the hypothalamic-pituitary-adrenal axis. POST-FINE NEEDLE ASPIRATION BIOPSY INVOLUTIVE CHANGES IN AN INCIDENTAL ADRENAL CORTICAL ADENOMA Figure 5-15 POST-FINE NEEDLE ASPIRATION BIOPSY INVOLUTIVE CHANGES IN AN INCIDENTAL ADRENAL CORTICAL ADENOMA Incidental nonfunctional...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). The diagnosis of pheochromocytoma must be considered in the workup of any patient with an adrenal mass. Failure to consider this in the differential diagnosis may result in a catecholamine crisis precipitated by anesthesia or tumor manipulation during biopsy or surgical resection, with resulting stroke and even...
Images
Figure 4-16
Published: 01 September 2024
DISSEMINATED ADENOVIRUS INFECTION Figure 4-16 DISSEMINATED ADENOVIRUS INFECTION A gastric biopsy from an immunocompromised individual shows strong nuclear positivity for adenovirus infection. (Courtesy of Dr. J. Greenson, University of Michigan, Ann Arbor, MI) More about this image found in DISSEMINATED ADENOVIRUS INFECTION A gastric biopsy from an immunocompromis...
Images
Figure 4-28
Published: 01 September 2024
EARLY MEASLES EXANTHEM Figure 4-28 EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, and early keratinocyte necrosis (A). MeV immunohistochemistry (B) demonstrates positivity in epidermal squamous epithelium. (Courtesy of the CDC IDPB) More about this image found in EARLY MEASLES EXANTHEM Skin biopsy shows spongiosis, mild parakeratosis, a...