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Book Chapter

Neck

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-7
ISBN: 978-1-933477-61-9
... primarily of childhood and young adulthood, although patients up to 74 years have been reported ( 137 ). There is a slight male predominance. The classic presentation, which yielded the name of the disease, is of bulky, painless, bilateral, cervical adenopathy with fever ( 136 ). Inguinal, axillary...
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Book Chapter

Ear and Temporal Bone

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... apocrine-type glands, typically arranged in lobules and clusters in the deep dermis below the level of the sebaceous glands. They are not active until puberty, matching the activity of axillary apocrine glands ( 6 ). The glands are composed of two cell types: an inner cuboidal-columnar secretory cell layer...
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Images
Figure 14-17

PLAGUE Typical plague buboes in the inguinal (A) and axillary (B) areas. (...

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in Systemic Infections > Pathology of Non-Helminth Infectious Diseases
Published: 01 September 2024
PLAGUE Figure 14-17 PLAGUE Typical plague buboes in the inguinal (A) and axillary (B) areas. (Courtesy of the CDC PHIL) More about this image found in PLAGUE Typical plague buboes in the inguinal (A) and axillary (B) areas. (...
Book Chapter

Systemic Infections

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of the CDC PHIL) Y. PESTIS VIRULENCE FACTORS Figure 14-16 Y. PESTIS VIRULENCE FACTORS PLAGUE Figure 14-17 PLAGUE Typical plague buboes in the inguinal (A) and axillary (B) areas. (Courtesy of the CDC PHIL) PLAGUE Figure 14-18 PLAGUE Necrosis of the distal phalanges of the hand...
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Book Chapter

Skin and Soft Tissue

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of nerves and skin adnexa, especially sweat glands. Eosinophils and local hemorrhage can be present at the site of the tick bite. In some cases, the inflammatory infiltrate may not contain plasma cells or eosinophils, and is mainly periadnexal in distribution ( 17 ). Erythematous lesions on the axillary...
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Book Chapter

Axillary Lymph Nodes

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... transcription polymerase chain reaction [RT-PCR]), but no regional lymph node metastases detected by histology or IHC. pN1: Micrometastases, or metastases in one to three axillary lymph nodes, and/or clinically negative internal mammary nodes with micro- or macrometastases detected by sentinel lymph node...
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Book Chapter

Pathologic Evaluation and Reporting of Breast and Axillary Lymph Node Specimens

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... nodes and axillary lymph node dissections As for non-neoadjuvant specimens:  Section at 2-mm intervals parallel to the long axis of the lymph node  Submit in entirety  For lymph nodes with grossly apparent metastatic carcinoma, a representative section of largest focus and any extracapsular...
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Images
Figure 14-18

SILICONE LYMPHADENOPATHY A: This intermediate-power image of an axillary l...

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in Axillary Lymph Nodes > Tumors of the Mammary Gland
Published: 01 January 2024
SILICONE LYMPHADENOPATHY Figure 14-18 SILICONE LYMPHADENOPATHY A: This intermediate-power image of an axillary lymph node shows multiple giant cells with clear cytoplasmic inclusions. B: At high power, and with the microscope condenser lowered, the refractile nature of the material in the giant More about this image found in SILICONE LYMPHADENOPATHY A: This intermediate-power image of an axillary l...
Images
Figure 14-19

GRANULOMATOUS LYMPHADENOPATHY Low- (A) and high- (B) power views of granul...

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in Axillary Lymph Nodes > Tumors of the Mammary Gland
Published: 01 January 2024
GRANULOMATOUS LYMPHADENOPATHY Figure 14-19 GRANULOMATOUS LYMPHADENOPATHY Low- (A) and high- (B) power views of granulomatous lymphadenopathy in axillary lymph nodes of a patient with breast carcinoma. Systemic and infectious etiologies always need to be excluded. More about this image found in GRANULOMATOUS LYMPHADENOPATHY Low- (A) and high- (B) power views of granul...
Book Chapter

Normal Anatomy

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... etiology . J Natl Cancer Inst   2014 ; 106 : dju286 . 47. Jordan   K , Laumann   A , Conrad   S , Medenica   M . Axillary mass in a 20-year-old woman. Diagnosis: axillary accessory breast tissue . Arch Dermatol   2001 ; 137 : 1367 - 72 . 48. O’Hara   MF , Page   DL...
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Book Chapter

Rare Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... inflammatory cell types ( fig. 12-2 ). Distinction from chronic inflammatory processes, invasive lobular carcinoma, lymphocytic mastopathy, or intraparenchymal lymph nodes can sometimes be challenging. Also, axillary lymph nodes may be involved by CLL/SLL, either in the presence or the absence of metastatic...
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Book Chapter

Male Breast Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... for some of the excess mortality in men ( 29 ). The median age at presentation of breast cancer in men is about 65 years (25 to 87 years), which is older than for women ( 15 , 16 ). The tumors are more often larger at presentation, and patients are more likely to have axillary lymph node involvement. High...
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Book Chapter

Inflammatory and Reactive Conditions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... . Breast involvement by extranodal Rosai-Dorfman disease: report of seven cases . Am J Surg Pathol   1997 ; 21 : 664 - 8 . 20. Tenny   SO , McGinness   M , Zhang   D , Damjanov   I , Fan   F . Rosai-Dorfman disease presenting as a breast mass and enlarged axillary lymph node...
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Book Chapter

Breast Lesions in Children and Adolescents

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... recurrences in any residual breast tissue and in the axillary tail may occur even after mastectomy ( 3 , 6 ). Antiestrogen therapies, such as Tamoxifen, have been reported to have some success ( 6 ). PTEN loss as a mechanism for the development of mammary hypertrophy has been postulated...
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Book Chapter

Nipple Disorders

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-13
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... - 46 . 22. Ozerdem   U , Swistel   A , Antonio   LB , Hoda   SA . Invasive Paget disease of the nipple: a brief review of the literature and report of the first case with axillary nodal metastases . Int J Surg Pathol   2014 ; 22 : 566 - 9 . 23. Duan   X , Sneige   N...
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Book Chapter

Fibroepithelial Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... stratify patients into those at greatest risk ( 40 , 41 ). Axillary lymph node sampling is not indicated as lymphatic spread is not a feature of phyllodes tumors; the value of adjuvant therapy is not well established. The NCCN guideline advises consideration of radiation therapy if recurrence would cause...
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Book Chapter

Mesenchymal Lesions

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...-differentiated” and “poorly differentiated” angiosarcoma, grading is not advised as most are associated with a poor outcome, and thus are best considered high-grade tumors ( 58 ). Wide local excision or mastectomy is usually the treatment of choice. Axillary lymph node dissection is not necessary, due to the low...
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Book Chapter

Invasive Carcinomas of the Breast

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... cells from breast carcinoma cells in axillary lymph nodes (see chapter 14 ) ( 119 ). Other immunohistochemical stains often used in differential diagnostic panels, such as CDX2, PAX8 and WT1, HMB-45, Melan A, TTF1, CD20, and CD3 are rarely positive in breast carcinoma. WT1 and TTF1 are the markers...
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Book Chapter

Venous and Lymphatic Disease

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... and nonseptated lesions . Obstet Gynecol   1996 ; 88 : 979 - 82 . 56. Michail   O , Michail   P , Kyriaki   D , Kolindou   A , Klonaris   C , Griniatsos   J . Rapid development of an axillary mass in an adult: a case of cystic hygroma . South Med J   2007 ; 100 : 845 - 9 . 57...
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Book Chapter

Connective Tissue Disorders

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Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch31
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... as early as infancy. Progressive enlargement increases the risk of type A dissection and aortic regurgitation, the latter relating to annular dilatation ( fig. 31-4 ). These aneurysms may also involve the subclavian and axillary arteries. ...
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