EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Figure 8-11 EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associated lymphocyte infiltrate (B), with pancytokeratin immunohistochemistry (C) confirm the epithelial nature of the neoplasm. More about this image found in EBV-ASSOCIATED NASOPHARYNGEAL CARCINOMA Desmoplastic stroma (A) and associ...

ZIKA CONGENITAL SYNDROME Figure 3-4 ZIKA CONGENITAL SYNDROME Microcephaly can be associated with this disease. (Courtesy of the CDC Zika Virus Webpage https://www.cdc.gov/zika/czs/index.html ) More about this image found in ZIKA CONGENITAL SYNDROME Microcephaly can be associated with this disease....

CHRONIC HCV HEPATITIS Figure 5-8 CHRONIC HCV HEPATITIS Associated steatosis (A) and scattered eosinophils (B,C) are clues to the diagnosis. More about this image found in CHRONIC HCV HEPATITIS Associated steatosis (A) and scattered eosinophils (...

PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS Figure 8-4 PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS The HIV patient has a hypercellular bone marrow (A) with numerous large atypical pronormoblasts (B). More about this image found in PARVOVIRUS B19-ASSOCIATED TRANSIENT APLASTIC CRISIS The HIV patient has a ...

EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Figure 8-6 EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Usually, there is a peripheral lymphocytosis and atypical lymphocytes (A,B) are seen on the peripheral blood smear. More about this image found in EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Usually, there is a peripheral lym...

EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Figure 8-8 EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Lymph node with architectural distortion (A) with focal capsular permeation by lymphoid cells (top), a polymorphic mononuclear infiltrate (B) with associated plasma cells (C) and focal mitotic activity (cen... More about this image found in EBV-ASSOCIATED INFECTIOUS MONONUCLEOSIS Lymph node with architectural dist...

EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Figure 8-9 EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Bone marrow trephine biopsy (A,B) and aspirate (C,D). More about this image found in EBV-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS Bone marrow trephine bio...

POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Figure 8-14 POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MONOMORPHIC TYPE Low-power view (A) plasmacytoma-like features (B) and positivity for EBER ISH (C). (Courtesy of Dr. S. As... More about this image found in POST-TRANSPLANT EBV-ASSOCIATED LYMPHOPROLIFERATIVE DISEASE (PTLD) OF THE MO...

PHASES OF HHV8 INFECTION, WITH ASSOCIATED GENE EXPRESSION Figure 8-15 PHASES OF HHV8 INFECTION, WITH ASSOCIATED GENE EXPRESSION More about this image found in PHASES OF HHV8 INFECTION, WITH ASSOCIATED GENE EXPRESSION

KAPOSI SARCOMA Figure 8-21 KAPOSI SARCOMA HHV8 latency-associated nuclear antigen (LANA) immunohistochemical assay shows typical punctate nuclear staining. More about this image found in KAPOSI SARCOMA HHV8 latency-associated nuclear antigen (LANA) immunohistoc...

HHV8-ASSOCIATED MULTICENTRIC CASTLEMAN DISEASE IN HIV PATIENT Figure 8-23 HHV8-ASSOCIATED MULTICENTRIC CASTLEMAN DISEASE IN HIV PATIENT A: An intra-abdominal lymph node shows an early germinal center and vascular hyalinization, surrounding concentric rims (“onion-skinning”) of lymphocytes and ass... More about this image found in HHV8-ASSOCIATED MULTICENTRIC CASTLEMAN DISEASE IN HIV PATIENT A: An intra-...

HIV CENTRAL NERVOUS SYSTEM DISEASE Figure 9-7 HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syndrome (HAD), with ventricular dilatation and sulcal widening. B: HIV encephalitis shows cortical white matter with multinucleated giant cell encephalitis (MGCE). C: HIV enceph... More about this image found in HIV CENTRAL NERVOUS SYSTEM DISEASE A: Brain in HIV-associated dementia syn...

VASCULOPATHY ASSOCIATED WITH HIV Figure 9-11 VASCULOPATHY ASSOCIATED WITH HIV A: Cerebral artery with severe intimal thickening and narrowing (endarteritis obliterans). B: HIV vasculitis in a cerebral artery, with lymphocytes infiltrating through the vessel wall. More about this image found in VASCULOPATHY ASSOCIATED WITH HIV A: Cerebral artery with severe intimal th...

HIV-ASSOCIATED NEPHROPATHY (HIVAN) Figure 9-19 HIV-ASSOCIATED NEPHROPATHY (HIVAN) A: Grossly enlarged kidney. B: Collapsing glomerulus with hypertrophied epithelial cells. C: Glomerular sclerosis demonstrated with a periodic acid methenamine (PAM) silver stain. D: Interstitial chronic inflamma... More about this image found in HIV-ASSOCIATED NEPHROPATHY (HIVAN) A: Grossly enlarged kidney. B: Collaps...

FIBROTIC TUBERCULOUS GRANULOMA Figure 12-59 FIBROTIC TUBERCULOUS GRANULOMA The granuloma has associated, entrapped black anthracotic pigment-containing macrophages. These granulomas may also calcify and enter the differential diagnosis of silicotic lung nodules, which are characterized by strikin... More about this image found in FIBROTIC TUBERCULOUS GRANULOMA The granuloma has associated, entrapped bla...

C. DIFFICILE ANTIBIOTIC-ASSOCIATED COLITIS Figure 13-25 C. DIFFICILE ANTIBIOTIC-ASSOCIATED COLITIS The patchy macroscopic yellow-white pseudomembranes bleed on abrasion. (Courtesy of Dr. L. W. Lamps, University of Michigan, Ann Arbor, MI) More about this image found in C. DIFFICILE ANTIBIOTIC-ASSOCIATED COLITIS The patchy mac...

CHRONIC H. PYLORI-ASSOCIATED GASTRITIS Figure 13-30 CHRONIC H. PYLORI-ASSOCIATED GASTRITIS A prominent lymphoplasmacytic mucosal infiltrate and interspersed secondary lymphoid follicles with germinal centers are present. More about this image found in CHRONIC H. PYLORI-ASSOCIATED GASTRITIS A prominent lympho...

INFECTIVE ENDOCARDITIS Figure 16-4 INFECTIVE ENDOCARDITIS The layered fibrin and associated inflammatory cells make up the valvular vegetation (A,B). A fungal Grocott methenamine silver (GMS) stain highlights scattered bacterial organisms (C), which may show altered morphologic and tinctorial cha... More about this image found in INFECTIVE ENDOCARDITIS The layered fibrin and associated inflammatory cell...

BARTONELLA-ASSOCIATED PELIOSIS Figure 17-5 BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone marrow (B) characteristic randomly distributed and cystic, blood-filled cavities are seen, which typify this disorder. Warthin-Starry silver stain (C) demonstrates numerous etiologic bacteria. More about this image found in BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone ...

EUMYCETOMA Figure 24-10 EUMYCETOMA There is swelling of the forefoot and multiple associated sinuses. (Courtesy of Division of Dermatology, University of the Witwatersrand, Johannesburg, South Africa) More about this image found in EUMYCETOMA There is swelling of the forefoot and multiple associated sinus...