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TYPICAL HPV-ASSOCIATED NONKERATINIZING SQUAMOUS CELL CARCINOMA Figure 2-6 TYPICAL HPV-ASSOCIATED NONKERATINIZING SQUAMOUS CELL CARCINOMA Ribbons of tumor line the surface of a tonsillar crypt, with pushing borders and no stromal desmoplasia. More about this image found in TYPICAL HPV-ASSOCIATED NONKERATINIZING SQUAMOUS CELL CARCINOMA Ribbons of ...

HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLASIA AND MULTINUCLEATION Figure 2-12 HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLASIA AND MULTINUCLEATION A: In anaplastic tumor cells, particularly in neck lymph node dissection specimens More about this image found in HPV-ASSOCIATED OROPHARYNGEAL SQUAMOUS CELL CARCINOMA WITH TUMOR CELL ANAPLA...

HUMAN PAPILLOMAVIRUS (HPV)-ASSOCIATED ORAL DYSPLASIA Figure 4-21 HUMAN PAPILLOMAVIRUS (HPV)-ASSOCIATED ORAL DYSPLASIA A: Compact, eosinophilic parakeratin overlying epithelium shows full-thickness dysplasia. B: Numerous karyorrhectic cells (black arrows) and apoptotic cells (blue arrows). C More about this image found in HUMAN PAPILLOMAVIRUS (HPV)-ASSOCIATED ORAL DYSPLASIA A: Compact, eosinophi...

FRICTIONAL KERATOSIS Figure 4-22 FRICTIONAL KERATOSIS A: Keratosis (arrows) associated with the parafunctional habit of tongue biting. B: Shaggy parakeratosis overlying acanthotic epithelium without dysplasia. Surface bacteria are seen more often in frictional keratosis from the tongue compared More about this image found in FRICTIONAL KERATOSIS A: Keratosis (arrows) associated with the parafunctio...

PSEUDOEPITHELIOMATOUS HYPERPLASIA Figure 6-33 PSEUDOEPITHELIOMATOUS HYPERPLASIA A: Blastomycosis-associated pseudoepitheliomatous hyperplasia shows submucosal and intraepithelial neutrophils and undulating, very mature squamous epithelium mimicking a well-differentiated neoplastic process. B More about this image found in PSEUDOEPITHELIOMATOUS HYPERPLASIA A: Blastomycosis-associated pseudoepithe...

METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARCINOMA Figure 7-22 METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARCINOMA Metastasis to a cervical lymph node showing a thin lining epithelium with smooth surface and scattered ciliated cells. More about this image found in METASTATIC CILIATED HUMAN PAPILLOMAVIRUS(HPV)-ASSOCIATED SQUAMOUS CELL CARC...

METASTATIC HPV-ASSOCIATED SQUAMOUS CELL CARCINOMA Figure 7-32 METASTATIC HPV-ASSOCIATED SQUAMOUS CELL CARCINOMA A: The FNA shows crowded nonkeratinizing squamous cells with enlarged, ovoid, hyperchromatic nuclei and scant cytoplasm. (Diff-Quik preparation) B: The corresponding cell block More about this image found in METASTATIC HPV-ASSOCIATED SQUAMOUS CELL CARCINOMA A: The FNA shows crowded...

METASTATIC SQUAMOUS CELL CARCINOMA VERSUS BRANCHIAL CLEFT CYST Figure 7-39 METASTATIC SQUAMOUS CELL CARCINOMA VERSUS BRANCHIAL CLEFT CYST A: p16 immunohistochemistry of a metastatic oropharyngeal HPV-associated nonkeratinizing SCC with cystic change shows strong, diffuse nuclear and cytoplasmic More about this image found in METASTATIC SQUAMOUS CELL CARCINOMA VERSUS BRANCHIAL CLEFT CYST A: p16 immu...

AMELOBLASTIC FIBROMA Figure 5-68 AMELOBLASTIC FIBROMA Panoramic radiograph shows a typical unilocular radiolucency in the left mandible associated with the unerupted second premolar. More about this image found in AMELOBLASTIC FIBROMA Panoramic radiograph shows a typical unilocular radio...

ENDOLYMPHATIC SAC TUMOR Figure 8-123 ENDOLYMPHATIC SAC TUMOR A cellular papillary proliferation is intimately associated with bone, showing remodeling and infiltration of the interstices. More about this image found in ENDOLYMPHATIC SAC TUMOR A cellular papillary proliferation is intimately a...

DESMOPLASTIC FIBROMA Figure 5-200 DESMOPLASTIC FIBROMA The fibroma is composed of fascicles of bland, uniform spindle cells with indistinct eosinophilic cytoplasm, associated with extracellular collagen fibers. More about this image found in DESMOPLASTIC FIBROMA The fibroma is composed of fascicles of bland, unifor...

PECOMA Figure 1-66 PECOMA A,B: PEComa is in the differential diagnosis of leiomyoma, identified below an intact epithelium. The epithelioid and spindled cells are associated with vessels; cleared to granular cytoplasm is present in cells with prominent nucleoli. More about this image found in PECOMA A,B: PEComa is in the differential diagnosis of leiomyoma, identifi...

OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Figure 2-46 OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Low magnification view shows vaguely nodular sheets of cells interspersed with some associated mature lymphocytes. More about this image found in OROPHARYNGEAL FOLLICULAR DENDRITIC CELL SARCOMA Low magnification view sho...

MIDDLE EAR NEUROENDOCRINE TUMOR Figure 8-102 MIDDLE EAR NEUROENDOCRINE TUMOR A: Multiple patterns are seen in this tumor, where delicate nuclear chromatin is noted. B: A concurrent cholesteatoma is intimately associated with a MeNET. More about this image found in MIDDLE EAR NEUROENDOCRINE TUMOR A: Multiple patterns are seen in this tumo...

NORMAL ANATOMY OF THE TONSILLAR TISSUES Figure 2-1 NORMAL ANATOMY OF THE TONSILLAR TISSUES At low power, portions of the oropharynx show invaginated crypt epithelium intimately associated with organized lymphoid tissue with prominent germinal centers. More about this image found in NORMAL ANATOMY OF THE TONSILLAR TISSUES At low power, portions of the orop...

CYSTIC METASTASIS Figure 2-5 CYSTIC METASTASIS Axial view computerized tomography (CT) scan of the neck shows cystic metastases (asterisks) from a human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC). More about this image found in CYSTIC METASTASIS Axial view computerized tomography (CT) scan of the neck...

GRANULAR CELL TUMOR Figure 4-38 GRANULAR CELL TUMOR A: Pseudoepitheliomatous hyperplasia overlying an unencapsulated granular cell tumor extending into the skeletal muscle. B: High-power view of the pseudoepitheliomatous hyperplasia associated with the granular cells. More about this image found in GRANULAR CELL TUMOR A: Pseudoepitheliomatous hyperplasia overlying an unen...

CENTRAL ODONTOGENIC FIBROMA Figure 5-96 CENTRAL ODONTOGENIC FIBROMA Amyloid-rich variant with small cords and nests of odontogenic epithelium with rounded amorphous eosinophilic pools of secreted amyloid protein (odontogenic ameloblast-associated protein [ODAM]). More about this image found in CENTRAL ODONTOGENIC FIBROMA Amyloid-rich variant with small cords and nest...

ONCOCYTIC CYSTADENOMA Figure 6-83 ONCOCYTIC CYSTADENOMA Low-magnification view of a typical multicystic oncocytic cystadenoma. Some of the spaces are more dilated, with obvious papillary projections, and others are mildly dilated and overlap with associated seromucinous glands More about this image found in ONCOCYTIC CYSTADENOMA Low-magnification view of a typical multicystic onco...