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Figure 13-12
Published: 01 September 2024
. pseudotuberculosis appendix involvement demonstrates lymphoid hyperplasia and epithelioid cell granuloma formation in relation to germinal centers. (Courtesy of Dr. L. W. Lamps, University of Michigan, Ann Arbor, MI) More about this image found in YERSINIA APPENDICITIS A–C: Yersinia enterocolitic...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... APPENDICITIS A–C: Yersinia enterocolitica infection, showing lymphoid hyperplasia (A) and focal germinal center neutrophil infiltration with early microabscess formation (B, arrow; C) are seen. D,E: Y. pseudotuberculosis appendix involvement demonstrates lymphoid hyperplasia and epithelioid...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-appendix01
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... 11.2 50 10.9 11.7 75 10.5 11.7 95 10.0 11.4 a Table created from data in reference 2 . b See Appendix 3 for descriptions of exclusionary conditions and number of cases per year. Cellular Feature (ref.) Measurement Explanatory Notes Cell number (entire heart) ( 11...
Images
Figure 39-48
Published: 15 November 2023
HETEROTAXY SYNDROME: THORACOABDOMINAL VISCERA Figure 39-48 HETEROTAXY SYNDROME: THORACOABDOMINAL VISCERA A: An in situ photograph at autopsy shows a midline liver with bilateral right lobes, a left-sided gallbladder, and intestinal malrotation with the cecum and appendix (arrow) in the left More about this image found in HETEROTAXY SYNDROME: THORACOABDOMINAL VISCERA A: An in situ photograph at ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of atrial myocardium differs from that of the ventricles (see Appendix 13 ). The relative volume of extracellular matrix in normal atrial myocardium is appreciably greater than that in the ventricles ( 39 ). Gross Findings. Atrial hypertrophy, dilatation, and fibrosis have been studied most extensively...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch03
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... above but also by the underlying disease state. Binucleate Myocytes. Approximately 25 percent of left ventricular myocytes and 20 percent of right ventricular myocytes are binucleate (see Appendix 13 ). After the age of 1 year, these percentages are unaffected by age, hypertrophy...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch34
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... are evaluated following sequential segmental analysis, for which a standardized form is provided ( Appendix 14 ). Secondary changes, such as hypertrophy, dilatation, hypoplasia, atrophy, and fibrosis, should be recorded, as should descriptions of interventional procedures. Myocardial sections...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch01
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., regardless of age or sex, and the mitral annulus is second. Aortic and pulmonary valves are the smallest and are similar in size. For all ages, the circumferences of all four valves increase over time, and in adults they are generally larger in men than women (see Appendix 11 ) ( 14 , 15 , 21 , 43...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch39
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... gallbladder, and intestinal malrotation with the cecum and appendix (arrow) in the left upper abdominal quadrant, in an infant with asplenia. B: The thoracoabdominal organs have been removed en bloc, showing a rightward cardiac apex, bilateral trilobed lungs, a midline symmetric liver with mirror-image right...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch02
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... thicknesses (see Appendix 11 ). However, these vary according to body size: somewhat less for smaller adults and more for larger individuals. Formalin fixation can increase left ventricular wall thickness by 10 percent. Rigor mortis and decomposition also affect myocardial thickness (see Postmortem Changes...
Images
Figure 7-32
Published: 01 August 2023
METASTATIC GOBLET CELL ADENOCARCINOMA OF THE APPENDIX Figure 7-32 METASTATIC GOBLET CELL ADENOCARCINOMA OF THE APPENDIX This tumor forms simple tubules that recall endometrioid adenocarcinoma. However, the pattern of ovarian stromal invasion with retention of intact cortical and medullary More about this image found in METASTATIC GOBLET CELL ADENOCARCINOMA OF THE APPENDIX This tumor forms sim...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., vasculitis is identified in the gonads, uterus, and gallbladder, and is often isolated ( 81 , 82 ). Polyarteritis-Like Single Organ Vasculitis. Incidental vasculitis indistinguishable from PAN is described in many organs, including the appendix, testis, gallbladder, liver, breast, and uterus ( fig. 30-40...
Images
Figure 16-37
Published: 01 August 2023
LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINATED PERITONEAL ADENOMUCINOSIS/WELL-DIFFERENTIATED MUCINOUS ADENOCARCINOMA OF APPENDIX) Figure 16-37 LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINATED PERITONEAL ADENOMUCINOSIS/WELL More about this image found in LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINA...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-15
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
..., breast, biliary system, appendix, and other less common sites. Immunohistochemistry helps identify the primary site ( Table 15-2 ) ( 34 ). Gastric signet ring cell adenocarcinomas have variable staining with CK7 and CK20. Approximately half of tumors are CDX2 positive. SATB2 is usually negative, but may...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-08
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... of a metastasis, even if no extraovarian primary tumor can be found  Does not distinguish primary vs. metastasis   SATB2+ consider appendix or colon met Consider adding SMAD4   SMAD4 loss: consider pancreas met CK20/CDX2 diffuse (usually also CK7-, SATB2)   Consider colon met a “Strong...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-16
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... tract, appendix, and breast ( fig. 16-30 ) ( 115 – 117 ). Metastases that resemble endometrioid carcinomas and mucinous carcinomas are detailed in corresponding sections of this chapter. METASTATIC MUCINOUS ADENOCARCINOMA COLONIZING FALLOPIAN MUCOSA Figure 16-28 METASTATIC MUCINOUS ADENOCARCINOMA...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-07
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... features and mitotic index (right) are more in keeping with colorectal adenocarcinoma. No confirmatory endometrioid features are present. METASTATIC GOBLET CELL ADENOCARCINOMA OF THE APPENDIX Figure 7-32 METASTATIC GOBLET CELL ADENOCARCINOMA OF THE APPENDIX This tumor forms simple tubules that recall...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... partially developed organs, such as bowel, appendix, external genitalia, and eyes are grossly identified. Sometimes the cysts are pigmented secondary to melanosis. Fetiform teratoma refers to a teratoma that resembles a malformed human fetus ( fig. 13-1C ). Clinical Features. Mature cystic...
Images
Figure 11-35
Published: 01 August 2022
APPENDIX TESTIS WITH ISCHEMIC DAMAGE Figure 11-35 APPENDIX TESTIS WITH ISCHEMIC DAMAGE A segment of the appendix testis is fibrotic with dystrophic calcification, likely the result of a prior episode of incomplete torsion with consequent ischemic damage. More about this image found in APPENDIX TESTIS WITH ISCHEMIC DAMAGE A segment of the appendix testis is f...
Images
Figure 11-33
Published: 01 August 2022
NORMAL APPENDIX TESTIS Figure 11-33 NORMAL APPENDIX TESTIS The structure projects from the testicular surface with a sawtooth profile. More about this image found in NORMAL APPENDIX TESTIS The structure projects from the testicular surface ...