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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of the anatomic relationships during adrenal gland development (see fig. 1-3 ), adrenal cortical tissue can be found later in life anywhere in the vicinity of the fetal adrenal primordium or along the line of descent of the gonads in males and females, including gonadal adnexal structures and, rarely, within...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to destruction of adnexal structures. CUTANEOUS LEISHMANIA ULCER Figure 28-5 CUTANEOUS LEISHMANIA ULCER Prominent peripheralization of amastigotes within macrophages, with prominent histiocytes and plasma cells (A,B). In about 30 percent of cutaneous cases, epithelioid cell granulomas...
Images
Published: 01 February 2024
CMN WITH ADNEXAL INVOLVEMENT Figure 2-6 CMN WITH ADNEXAL INVOLVEMENT Several nests of melanocytes are present within and immediately around adnexal epithelium. More about this image found in CMN WITH ADNEXAL INVOLVEMENT Several nests of melanocytes are present with...
Images
Published: 01 February 2024
LENTIGO MALIGNA MELANOMA IN SITU WITH ADNEXAL INVOLVEMENT Figure 13-7 LENTIGO MALIGNA MELANOMA IN SITU WITH ADNEXAL INVOLVEMENT The tumor cells proliferate at the dermoepidermal junction and extend into the superficial portion adnexal epithelium (arrows). More about this image found in LENTIGO MALIGNA MELANOMA IN SITU WITH ADNEXAL INVOLVEMENT The tumor cells ...
Images
Published: 01 February 2024
JUNCTIONAL SPITZ NEVUS Figure 7-6 JUNCTIONAL SPITZ NEVUS A: Small circumscribed lesion with junctional nests of spindle and epithelioid melanocytes. B: The junctional nests extend into adnexal structures. More about this image found in JUNCTIONAL SPITZ NEVUS A: Small circumscribed lesion with junctional nests...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... FINDINGS Lentigo Maligna Melanoma in Situ (LM-MIS) LM (LM-MIS) in its classic form is characterized by a proliferation of predominantly solitary units of melanocytes at the dermoepidermal and adnexal-stromal junction ( figs. 13-2 – 13-4 ) ( 1 , 12 ). Frequently, a few suprabasilar melanocytes are also...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-02
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... or subcutis, occasionally fascia or muscle Perivascular, periadnexal, and perineural growth Adnexal colonization Splaying (single filing, Indian filing) of melanocytes between undisturbed collagen bundles Increased terminal hairs Junctional component may show atypical features, including...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... displayed by atypical acral nevi that overlap with melanoma include pagetoid growth and/or lentiginous growth with adnexal involvement ( 10 ). Pagetoid growth (pagetosis) is reported in up to one third of acral nevi; the pagetoid spread, however, is usually focal and not florid or chaotic ( fig. 5-2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-09
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... WITH A CONVENTIONAL NEVUS (COMBINED NEVUS) Figure 9-4 DEEP PENETRATING NEVUS ASSOCIATED WITH A CONVENTIONAL NEVUS (COMBINED NEVUS) This lesion is limited to the papillary and superficial reticular dermis. Tumor cells tend to grow along neurovascular and adnexal structures, and often display plexiform features (see...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the potential for diagnostic confusion with skin adnexal (sebaceous or sweat gland) neoplasms, metastatic renal cell carcinoma, or xanthomatous histiocytic proliferations. DEEP PENETRATING NEVUS-LIKE (PLEXIFORM) MELANOMA Some melanomas may be confused with, or arise in association with, a deep penetrating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... Usually confined to dermis Often extending deep into subcutis Melanin pigment usually seen Usually amelanotic Little or no atypia Nuclear atypia common Neurotropism common Neurotropism common Tropism for adnexal structures No tropism for adnexal structures Usually no mitoses...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-15
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the development of other melanoma subtypes, in which the intraepidermal or intra-adnexal melanoma cells do not extend horizontally beyond the invasive tumor component. Thus, melanomas that may have started as conventional (superficial spreading, acral, or lentigo maligna) melanoma, could later meet criteria...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... the periadnexal stroma, the best reference point from where to measure tumor thickness may sometimes be the center of the adnexal epithelium and not the overlying epidermis ( 4 ). BRESLOW THICKNESS OF AN ULCERATED MELANOMA Figure 23-2 BRESLOW THICKNESS OF AN ULCERATED MELANOMA A: Partial punch biopsy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... be found, often around an adnexal structure and discontinuous with the scar. Repigmentation of a Scar. Repigmentation of a scar is a common phenomenon following excisions of melanocytic or nonmelanocytic lesions. Clinically, this is characterized by hyperpigmented lentigo-like macules, hyperpigmented...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... The separate melanocyte populations of a combined nevus tend to blend with each other or “respect” each other as well as adnexal structures. With a melanoma associated with a nevus there is an impression that the melanoma displaces, compresses, or overgrows the nevus remnant as well as normal skin structures...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-18
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... is recognized as a distinctly different nodule with high cellularity and epithelioid atypia ( fig. 18-1 ). The melanoma is entirely intradermal, with no associated in situ component in the epidermis or adnexal structures. MELANOMA ARISING IN ASSOCIATION WITH A BLUE NEVUS Figure 18-1 MELANOMA ARISING...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... that are typically entirely intradermal ( fig. 3-8 ). Adnexal involvement is common. COMPOUND MELANOCYTIC NEVUS Figure 3-5 COMPOUND MELANOCYTIC NEVUS Melanocytes are present both at the dermoepidermal junction as well as in the superficial dermis. POLYPOID COMPOUND (UNNA) MELANOCYTIC NEVUS Figure 3-6 POLYPOID...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-07
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... in the lower spinous cell layer. JUNCTIONAL SPITZ NEVUS Figure 7-6 JUNCTIONAL SPITZ NEVUS A: Small circumscribed lesion with junctional nests of spindle and epithelioid melanocytes. B: The junctional nests extend into adnexal structures. COMPOUND SPITZ NEVUS Figure 7-7 COMPOUND SPITZ NEVUS A,B: Grossly...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-13
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... resembling a skin adnexal eccrine tumor ( 14 ). Clinical Features. These rare lesions present as a palpable or image-detected mass or calcifications in the subareolar region. Occasionally, itchiness, tenderness, or discharge occur. Fungating lesions of the nipple have been reported in longstanding...
Images
Published: 01 August 2023
HIGH-GRADE SEROUS CARCINOMA FORMING AN ADNEXAL MASS Figure 16-3 HIGH-GRADE SEROUS CARCINOMA FORMING AN ADNEXAL MASS The fallopian tube (arrow) disappears into the mass, and the tubal fimbria are not visible. This overgrowth of the tubal fimbria is presumptive evidence of a primary tubal high-grad... More about this image found in HIGH-GRADE SEROUS CARCINOMA FORMING AN ADNEXAL MASS The fallopian tube (ar...
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