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Images
Published: 01 January 2024
FLAT EPITHELIAL ATYPIA Figure 3-3 FLAT EPITHELIAL ATYPIA A: Low power shows the variably dilated acini of the TDLU. The spaces have round, rigid contours. Secretions and calcifications are present in the acinar lumens. B: At higher power, the cuboidal nature of the epithelial cells becomes More about this image found in FLAT EPITHELIAL ATYPIA A: Low power shows the variably dilated acini of th...
Images
Published: 01 January 2024
as the striking nuclear atypia. Some abortive micropapillations are present and in some spaces, the cells are sufficiently proliferative to obliterate or partially obliterate the acinar lumens (C, left and lower center field and D). More about this image found in CYSTIC HYPERSECRETORY DUCTAL CARCINOMA IN SITU A: At low power, expansion ...
Images
Published: 15 November 2023
goblet cells. D: Pancreatic acinar tissue is within the cardiac teratoma. More about this image found in CARDIAC TERATOMA A: Multiple symmetric cysts are seen in both fibrous and ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-03
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
.... Some abortive micropapillations are present and in some spaces, the cells are sufficiently proliferative to obliterate or partially obliterate the acinar lumens (C, left and lower center field and D). CYSTIC HYPERSECRETORY CHANGE Figure 3-34 CYSTIC HYPERSECRETORY CHANGE A: Low power shows dilated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... into the acinar lumens ( fig. 2-24 ). The lumens contain eosinophilic secretory material and, as mentioned above, may contain calcifications, which characteristically show concentric lamellations. Pregnancy-like hyperplasia and cystic secretory hyperplasia, which have some morphologic similarities to secretory...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... an intracanalicular or a pericanalicular growth pattern. The intracanalicular pattern is characterized by greater elongation of the ducts with compression of those epithelial elements by the stromal component ( figs. 5-2 , 5-3 ). The pericanalicular pattern is recognized by the more open glandular or acinar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...: Pancreatic acinar tissue is within the cardiac teratoma. REFERENCES REFERENCES 1. Billmire D , Vinocur C , Rescorla F , et al . Malignant mediastinal germ cell tumors: an intergroup study . J Pediatr Surg 2001 ; 36 : 18 - 24 . 2. Tollens T , Casselman F , Devlieger...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch32
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... without an appreciable change in pulmonary vascular resistance. Extensive loss of the intra-acinar microcirculation may prevent this response and contribute to the development of pulmonary hypertension. Small venules travel within alveolar walls and are similar to pulmonary arterioles in both location...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch34
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... a Grade Lesions in Muscular Pulmonary Arteries Reversible 1A Muscular extension into arterioles Yes 1B Medial hypertrophy Yes 1C Loss of intra-acinar arteries Yes b 2 Concentric intimal proliferation Yes 3 Concentric laminar intimal fibrosis Borderline c...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-09
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
...Table 9-1 HISTOLOGIC FEATURES DISTINGUISHING ACINAR CELL CARCINOMA FROM WELL-DIFFERENTIATED PANCREATIC NEUROENDOCRINE TUMOR (PanNET) Feature Acinar Cell Carcinoma PanNET Circumscription ++ ++ Degree of cellularity +++ +++ Amount of stroma +/- +/++ Acinar pattern...
Images
Published: 01 August 2023
METASTATIC ACINAR CELL CARCINOMA OF PANCREAS Figure 7-34 METASTATIC ACINAR CELL CARCINOMA OF PANCREAS Left: Tubules are lined by cells with notable cytoplasmic eosinophilic granularity. Right: The tumor resembles endometrioid adenocarcinoma. (Courtesy of Dr. O. Basturk, New York, NY) More about this image found in METASTATIC ACINAR CELL CARCINOMA OF PANCREAS Left: Tubules are lined by ce...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-07
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... at high power discloses pseudostratified, darkly stained nuclei with numerous apical mitoses. C: The diagnosis is confirmed with a probe for high-risk HPV using in situ hybridization. Metastatic acinar carcinoma of pancreas is yet another tumor type that can feature tubules, and cribriform...
Images
Published: 01 March 2023
NON-NEOPLASTIC ACINAR CELLS AND ACINAR CELL CARCINOMA Figure 9-28 NON-NEOPLASTIC ACINAR CELLS AND ACINAR CELL CARCINOMA Neoplastic acinar cells have hyperchromatic chromatin and high nuclear: cytoplasmic ratio (left). On the right, cytoplasmic granularity is decreased in acinar cell carcinoma More about this image found in NON-NEOPLASTIC ACINAR CELLS AND ACINAR CELL CARCINOMA Neoplastic acinar ce...
Images
Published: 01 March 2023
ACINAR EPITHELIAL CELL Figure 1-10 ACINAR EPITHELIAL CELL Electron micrograph of acinar cells (right) juxtaposed with centroacinar cells (left). Acinar cells have luminal edge microvilli and round, electron-dense zymogen granules, whereas centroacinar cells have luminal microvilli and no zymogen More about this image found in ACINAR EPITHELIAL CELL Electron micrograph of acinar cells (right) juxtapo...
Images
Published: 01 March 2023
ACINAR EPITHELIAL CELLS Figure 1-11 ACINAR EPITHELIAL CELLS Aspirate smears of non-neoplastic acinar cells demonstrate a fairly cohesive grape-like clustering architecture, with stroma and single rosettes, some single cells, and a few stripped epithelial nuclei (direct smear; Papanicolaou). More about this image found in ACINAR EPITHELIAL CELLS Aspirate smears of non-neoplastic acinar cells dem...
Images
Published: 01 March 2023
ACINAR EPITHELIAL CELLS Figure 1-12 ACINAR EPITHELIAL CELLS Individual acinar cells are polygonal, with round central nuclei, generally well-defined nucleoli, and abundant granular cytoplasm. Left: Cells fixed in ethanol and stained with hematoxylin and eosin (H&E) highlight the nuclear More about this image found in ACINAR EPITHELIAL CELLS Individual acinar cells are polygonal, with round ...
Images
Published: 01 March 2023
ACINAR CELL NODULE Figure 1-21 ACINAR CELL NODULE Acinar cell nodules are defined as aggregates of enlarged non-neoplastic acinar cells that are distinguished from the surrounding acinar cells by the pale tinctorial staining qualities of the cytoplasm. More about this image found in ACINAR CELL NODULE Acinar cell nodules are defined as aggregates of enlarg...
Images
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-3 ACINAR CELL CARCINOMA A: Acinar cell carcinoma arising in the head of the pancreas with polypoid extension into the duodenum. B: The neoplasm is tan to pink and circumscribed, and shows focal hemorrhage. C: This 15-cm tumor shows a central degenerative cyst. More about this image found in ACINAR CELL CARCINOMA A: Acinar cell carcinoma arising in the head of the ...
Images
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-5 ACINAR CELL CARCINOMA Top: At low power, acinar cell carcinomas are circumscribed and surrounded by a fibrous pseudocapsule into which mushroom-like projections may grow. Bottom: Rarely, there is polypoid growth into the pancreatic ducts; non-neoplastic ductal More about this image found in ACINAR CELL CARCINOMA Top: At low power, acinar cell carcinomas are circum...
Images
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-8 ACINAR CELL CARCINOMA The acinar pattern shows pinpoint central lumens (left) and eosinophilic apical cytoplasm (right). More about this image found in ACINAR CELL CARCINOMA The acinar pattern shows pinpoint central lumens (le...
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